39 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bma-cdk-9	BMA-CDK-9; Belongs to the protein kinase superfamily. (424 aa)
	Bm9183	Bm9183. (519 aa)
	Bm1_35085	Bm10134. (500 aa)
	bma-ama-1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1870 aa)
	Bm1_39230	Bm10999. (609 aa)
	bma-fcp-1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (576 aa)
	Bm8072	Bm8072. (527 aa)
	bma-tceb-3	Bm9930. (461 aa)
	bma-pafo-1	Bm2949. (549 aa)
	bma-spt-4	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (119 aa)
	Bm1_50305	Bm10523. (231 aa)
	Bm1_26995	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	Bm1995	Bm1995. (711 aa)
	bma-rpb-2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1171 aa)
	Bm1_18530	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (685 aa)
	bma-rpb-12	BMA-RPB-12. (63 aa)
	bma-rpb-7	BMA-RPB-7. (174 aa)
	Bm6833	Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (83 aa)
	Bm8628	Bm8628. (543 aa)
	Bm1_52725	Bm1693, isoform d; Bm1693, isoform f. (476 aa)
	Bm4523	Bm4523, isoform j; Bm4523, isoform o. (1197 aa)
	Bm1_17615	Bm5993, isoform b. (305 aa)
	Bm1_52995	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	bma-cdk-12	BMA-CDTL-7. (995 aa)
	Bm1_22590	Uncharacterized protein. (670 aa)
	A0A5S6PCX2	Uncharacterized protein. (564 aa)
	Bm1_14360	Uncharacterized protein. (1693 aa)
	A0A5S6PDE4	Uncharacterized protein. (105 aa)
	A0A5S6PF86	Bm1813. (1161 aa)
	A0A5S6PFG5	Bm1813. (1416 aa)
	A0A5S6PFH0	Bm1813. (1375 aa)
	A0A5S6PFV9	Uncharacterized protein. (97 aa)
	Bm1_25170	Bm2020, isoform a. (538 aa)
	Bm1_13230	Bm3332, isoform c; Bm3332, isoform f. (524 aa)
	Bm1_50345	BMA-CCNK-1. (245 aa)
	A0A5S6PWZ0	Bm8628. (473 aa)
	Bm1_10890	Immunodominant antigen homologue, putative. (798 aa)
	A0A5S6PY43	Bm97. (247 aa)
	A0A5S6PYS6	Bm97. (80 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PCX2	A0A5S6PDE4	A0A5S6PCX2	A0A5S6PDE4	Uncharacterized protein.	Uncharacterized protein.	0.719
A0A5S6PCX2	A0A5S6PF86	A0A5S6PCX2	A0A5S6PF86	Uncharacterized protein.	Bm1813.	0.571
A0A5S6PCX2	A0A5S6PFG5	A0A5S6PCX2	A0A5S6PFG5	Uncharacterized protein.	Bm1813.	0.571
A0A5S6PCX2	A0A5S6PFH0	A0A5S6PCX2	A0A5S6PFH0	Uncharacterized protein.	Bm1813.	0.571
A0A5S6PCX2	Bm1_13230	A0A5S6PCX2	A0A5S6PJU2	Uncharacterized protein.	Bm3332, isoform c; Bm3332, isoform f.	0.798
A0A5S6PCX2	Bm1_17615	A0A5S6PCX2	A0A1P6C6E2	Uncharacterized protein.	Bm5993, isoform b.	0.591
A0A5S6PCX2	Bm1_18530	A0A5S6PCX2	A0A0K0J6D4	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.762
A0A5S6PCX2	Bm1_25170	A0A5S6PCX2	A0A5S6PGH7	Uncharacterized protein.	Bm2020, isoform a.	0.437
A0A5S6PCX2	Bm1_26995	A0A5S6PCX2	A0A0K0J039	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.505
A0A5S6PCX2	Bm1_50305	A0A5S6PCX2	A0A0K0INJ4	Uncharacterized protein.	Bm10523.	0.437
A0A5S6PCX2	Bm1_52725	A0A5S6PCX2	A0A1P6BNQ2	Uncharacterized protein.	Bm1693, isoform d; Bm1693, isoform f.	0.939
A0A5S6PCX2	Bm1_52995	A0A5S6PCX2	A0A1P6CBC0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.624
A0A5S6PCX2	Bm9183	A0A5S6PCX2	A0A0H5S4S2	Uncharacterized protein.	Bm9183.	0.437
A0A5S6PCX2	bma-ama-1	A0A5S6PCX2	A0A0H5S9G0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.437
A0A5S6PCX2	bma-fcp-1	A0A5S6PCX2	A0A0H5SGE9	Uncharacterized protein.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.461
A0A5S6PCX2	bma-pafo-1	A0A5S6PCX2	A0A0J9XVL8	Uncharacterized protein.	Bm2949.	0.538
A0A5S6PCX2	bma-rpb-12	A0A5S6PCX2	A0A0K0JAQ0	Uncharacterized protein.	BMA-RPB-12.	0.527
A0A5S6PCX2	bma-rpb-2	A0A5S6PCX2	A0A0K0J5T8	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.654
A0A5S6PCX2	bma-rpb-7	A0A5S6PCX2	A0A0K0JPP7	Uncharacterized protein.	BMA-RPB-7.	0.642
A0A5S6PCX2	bma-spt-4	A0A5S6PCX2	A0A0J9XWN9	Uncharacterized protein.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.662