42 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bm1_31220	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (849 aa)
	bma-aldo-2	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (382 aa)
	bma-pgk-1	Phosphoglycerate kinase. (415 aa)
	bma-fbp-1	BMA-FBP-1; Belongs to the FBPase class 1 family. (355 aa)
	bma-aldo-1	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	Bm1_35895	Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
	Bm3204	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (237 aa)
	Bm1_27085	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (335 aa)
	bma-hxk-1.1	Phosphotransferase. (450 aa)
	bma-rpia-1	BMA-RPIA-1, isoform c. (260 aa)
	bma-men-1	Malic enzyme. (634 aa)
	Bm1_35915	Pyruvate kinase; Belongs to the pyruvate kinase family. (140 aa)
	Bm1_41940	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	bma-tpi-1	Triosephosphate isomerase. (247 aa)
	Bm6539	Bm6539; Belongs to the phosphohexose mutase family. (586 aa)
	bma-pdha-1.1	Bm11079. (397 aa)
	Bm1_10280	BMA-TKT-1; Transketolase. (622 aa)
	Bm1_36755	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (540 aa)
	bma-tald-1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (322 aa)
	Bm1_38705	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (179 aa)
	Bm14809	Bm14809. (119 aa)
	Bm1_52850	Bm1963. (473 aa)
	Bm1_55785	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (347 aa)
	Bm1_35910	Pyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
	bma-pygl-1	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa)
	bma-pck-1	BMA-PCK-1, isoform b. (373 aa)
	Bm7089	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (784 aa)
	Bm13954	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (543 aa)
	Bm13963	UTP--glucose-1-phosphate uridylyltransferase. (499 aa)
	Bm14017	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (252 aa)
	Bm2622	Bm2622. (466 aa)
	A0A5S6P7D1	Uncharacterized protein. (80 aa)
	A0A5S6P7D5	Uncharacterized protein. (94 aa)
	Bm1_16455	Uncharacterized protein. (421 aa)
	Bm1_15740	Bm13746, isoform a. (571 aa)
	A0A5S6PB14	6-phosphogluconate dehydrogenase, decarboxylating. (489 aa)
	A0A5S6PFE9	Ribokinase. (307 aa)
	A0A5S6PIQ6	Bm2865. (450 aa)
	Bm1_43730	L-lactate dehydrogenase. (334 aa)
	A0A5S6PKC0	Uncharacterized protein. (232 aa)
	Bm1_53540	Bm6642, isoform a. (589 aa)
	G3PD	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6P7D1	A0A5S6PB14	A0A5S6P7D1	A0A5S6PB14	Uncharacterized protein.	6-phosphogluconate dehydrogenase, decarboxylating.	0.767
A0A5S6P7D1	A0A5S6PFE9	A0A5S6P7D1	A0A5S6PFE9	Uncharacterized protein.	Ribokinase.	0.415
A0A5S6P7D1	Bm13954	A0A5S6P7D1	A0A1P6BM06	Uncharacterized protein.	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	0.422
A0A5S6P7D1	Bm13963	A0A5S6P7D1	A0A1P6BMH5	Uncharacterized protein.	UTP--glucose-1-phosphate uridylyltransferase.	0.418
A0A5S6P7D1	Bm14017	A0A5S6P7D1	A0A1U7F107	Uncharacterized protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.505
A0A5S6P7D1	Bm14809	A0A5S6P7D1	A0A0K0J1S6	Uncharacterized protein.	Bm14809.	0.798
A0A5S6P7D1	Bm1_10280	A0A5S6P7D1	A0A0K0IYT1	Uncharacterized protein.	BMA-TKT-1; Transketolase.	0.791
A0A5S6P7D1	Bm1_15740	A0A5S6P7D1	A0A5S6PAF8	Uncharacterized protein.	Bm13746, isoform a.	0.790
A0A5S6P7D1	Bm1_16455	A0A5S6P7D1	A0A5S6P908	Uncharacterized protein.	Uncharacterized protein.	0.422
A0A5S6P7D1	Bm1_27085	A0A5S6P7D1	A0A0H5SQ52	Uncharacterized protein.	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.	0.513
A0A5S6P7D1	Bm1_31220	A0A5S6P7D1	A0A0H5S2N9	Uncharacterized protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.855
A0A5S6P7D1	Bm1_35895	A0A5S6P7D1	A0A0H5S8I5	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.798
A0A5S6P7D1	Bm1_35910	A0A5S6P7D1	A0A0K0JAY7	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.798
A0A5S6P7D1	Bm1_35915	A0A5S6P7D1	A0A0J9XXB1	Uncharacterized protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.798
A0A5S6P7D1	Bm1_36755	A0A5S6P7D1	A0A0K0IYU1	Uncharacterized protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.501
A0A5S6P7D1	Bm1_41940	A0A5S6P7D1	A0A0J9XXG7	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.889
A0A5S6P7D1	Bm1_43730	A0A5S6P7D1	A0A5S6PK92	Uncharacterized protein.	L-lactate dehydrogenase.	0.749
A0A5S6P7D1	Bm1_52850	A0A5S6P7D1	A0A0K0J3Y0	Uncharacterized protein.	Bm1963.	0.448
A0A5S6P7D1	Bm1_53540	A0A5S6P7D1	A0A5S6PTJ4	Uncharacterized protein.	Bm6642, isoform a.	0.412
A0A5S6P7D1	Bm3204	A0A5S6P7D1	A0A0H5SHF9	Uncharacterized protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.564