(38 nodes) Protein kinase regulator activity network (Brugia malayi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bma-cks-1	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (92 aa)
	Bm4960	Bm4960. (79 aa)
	A0A5S6PW82	Uncharacterized protein. (400 aa)
	A0A5S6PWQ5	Uncharacterized protein. (483 aa)
	Bm1_28030	Bm4790. (477 aa)
	Bm1_02025	Uncharacterized protein. (291 aa)
	A0A5S6PTG8	Uncharacterized protein. (335 aa)
	A0A5S6PVH9	Uncharacterized protein. (562 aa)
	Bm1_55065	Bm8349. (337 aa)
	bma-rla-1	BMA-RLA-1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (117 aa)
	bma-aakg-4	BMA-AAKG-4. (423 aa)
	Bm1_50355	Bm3241. (309 aa)
	bma-gcn-1	Bm6680. (2625 aa)
	bma-aakg-1	BMA-AAKG-1. (633 aa)
	Bm1_17390	Bm3883. (210 aa)
	Bm1_27665	Bm10275; Belongs to the cyclin family. (469 aa)
	Bm3925	Bm3925, isoform b; Bm3925, isoform c. (202 aa)
	Bm9735	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (202 aa)
	Bm1_44925	BMA-CYY-1; Belongs to the cyclin family. (353 aa)
	bma-nsy-4	BMA-NSY-4. (309 aa)
	Bma-cki-1	BMA-CKI-1. (204 aa)
	Bm3210	Bm3210; Bm3210; Bm4261, isoform a; Bm4261, isoform a; Belongs to the small heat shock protein (HSP20) family. (177 aa)
	Bm1_52060	BMA-DBL-1. (431 aa)
	bma-cya-1	BMA-CYA-1; Belongs to the cyclin family. (527 aa)
	A0A5S6PR95	Uncharacterized protein. (459 aa)
	bma-sek-1	BMA-SEK-1, isoform a; Belongs to the protein kinase superfamily. (382 aa)
	bma-cyh-1	BMA-CYH-1. (320 aa)
	bma-cic-1	BMA-CIC-1; Belongs to the cyclin family. (317 aa)
	bma-elpc-4	BMA-ELPC-4. (344 aa)
	Bm6591	Bm6045, isoform b; Belongs to the small heat shock protein (HSP20) family. (158 aa)
	A0A5S6P8S5	BMA-TAG-144, isoform b. (1341 aa)
	A0A5S6P8S6	BMA-TAG-144, isoform b. (1362 aa)
	Bm1_02525	Bm12598. (665 aa)
	A0A5S6PJT8	BMA-TIR-1, isoform b; BMA-TIR-1, isoform e. (775 aa)
	Bm1_50345	BMA-CCNK-1. (245 aa)
	A0A5S6PPN9	BMA-KIN-2. (251 aa)
	A0A5S6PPZ3	BMA-KIN-2. (364 aa)
	Bm1_33380	Bm13872. (336 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PJT8	bma-sek-1	A0A5S6PJT8	A0A0H5SCQ5	BMA-TIR-1, isoform b; BMA-TIR-1, isoform e.	BMA-SEK-1, isoform a; Belongs to the protein kinase superfamily.	0.521
A0A5S6PTG8	Bm1_33380	A0A5S6PTG8	A0A0K0IZC6	Uncharacterized protein.	Bm13872.	0.972
A0A5S6PTG8	bma-aakg-1	A0A5S6PTG8	A0A0J9Y2D3	Uncharacterized protein.	BMA-AAKG-1.	0.401
A0A5S6PVH9	A0A5S6PW82	A0A5S6PVH9	A0A5S6PW82	Uncharacterized protein.	Uncharacterized protein.	0.544
A0A5S6PVH9	A0A5S6PWQ5	A0A5S6PVH9	A0A5S6PWQ5	Uncharacterized protein.	Uncharacterized protein.	0.547
A0A5S6PW82	A0A5S6PVH9	A0A5S6PW82	A0A5S6PVH9	Uncharacterized protein.	Uncharacterized protein.	0.544
A0A5S6PWQ5	A0A5S6PVH9	A0A5S6PWQ5	A0A5S6PVH9	Uncharacterized protein.	Uncharacterized protein.	0.547
Bm1_02025	Bm1_27665	A0A5S6PSF1	A0A0J9Y7A7	Uncharacterized protein.	Bm10275; Belongs to the cyclin family.	0.699
Bm1_02025	Bm1_50345	A0A5S6PSF1	A0A5S6PLL3	Uncharacterized protein.	BMA-CCNK-1.	0.543
Bm1_02025	Bm1_55065	A0A5S6PSF1	A0A5S6PVV4	Uncharacterized protein.	Bm8349.	0.526
Bm1_02025	Bma-cki-1	A0A5S6PSF1	A0A0K0JJE9	Uncharacterized protein.	BMA-CKI-1.	0.957
Bm1_02025	bma-cks-1	A0A5S6PSF1	A0A0H5SHD8	Uncharacterized protein.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.832
Bm1_02025	bma-cya-1	A0A5S6PSF1	A0A0H5SBD8	Uncharacterized protein.	BMA-CYA-1; Belongs to the cyclin family.	0.650
Bm1_02025	bma-cyh-1	A0A5S6PSF1	A0A0H5SDL0	Uncharacterized protein.	BMA-CYH-1.	0.776
Bm1_02525	Bm1_27665	A0A5S6P972	A0A0J9Y7A7	Bm12598.	Bm10275; Belongs to the cyclin family.	0.716
Bm1_02525	bma-cya-1	A0A5S6P972	A0A0H5SBD8	Bm12598.	BMA-CYA-1; Belongs to the cyclin family.	0.585
Bm1_27665	Bm1_02025	A0A0J9Y7A7	A0A5S6PSF1	Bm10275; Belongs to the cyclin family.	Uncharacterized protein.	0.699
Bm1_27665	Bm1_02525	A0A0J9Y7A7	A0A5S6P972	Bm10275; Belongs to the cyclin family.	Bm12598.	0.716
Bm1_27665	Bm1_50345	A0A0J9Y7A7	A0A5S6PLL3	Bm10275; Belongs to the cyclin family.	BMA-CCNK-1.	0.556
Bm1_27665	Bm1_50355	A0A0J9Y7A7	A0A0H5SAE8	Bm10275; Belongs to the cyclin family.	Bm3241.	0.485