(22 nodes) Integral component of mitochondrial inner membrane network (Brugia malayi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A5S6PSD7	Bm6438. (725 aa)
	Bma-mcu-1	BMA-MCU-1. (347 aa)
	bma-coa-3	Bm3837. (139 aa)
	Bm5425	Bm5425. (324 aa)
	Bm6179	Bm6179. (89 aa)
	Bm1_51160	Bm5014, isoform a. (358 aa)
	bma-mpc-1	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (125 aa)
	bma-mpc-2.1	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (131 aa)
	bma-oxa-1	Bm12987. (399 aa)
	bma-timm-23.5	Bm14744. (255 aa)
	Bm4316	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (128 aa)
	Bm1_39320	Bm6418. (166 aa)
	A0A5S6PSG4	Bm6438. (747 aa)
	bma-timm-23.1	Bm12872, isoform a; Bm12872, isoform a; Bm12909; Bm12909. (148 aa)
	bma-coq-2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (347 aa)
	A0A5S6P9B8	Bm12825, isoform a. (246 aa)
	A0A5S6PAY8	Bm13945, isoform c. (596 aa)
	A0A5S6PGQ9	Sidoreflexin. (333 aa)
	A0A5S6PGX8	Sidoreflexin. (240 aa)
	A0A5S6PN63	BMA-MCU-1. (268 aa)
	Bm1_07760	MICOS complex subunit. (193 aa)
	Bm1_35025	Sidoreflexin. (325 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PAY8	bma-coq-2	A0A5S6PAY8	A0A1U7F4B8	Bm13945, isoform c.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.542
A0A5S6PN63	A0A5S6PSD7	A0A5S6PN63	A0A5S6PSD7	BMA-MCU-1.	Bm6438.	0.416
A0A5S6PN63	A0A5S6PSG4	A0A5S6PN63	A0A5S6PSG4	BMA-MCU-1.	Bm6438.	0.416
A0A5S6PSD7	A0A5S6PN63	A0A5S6PSD7	A0A5S6PN63	Bm6438.	BMA-MCU-1.	0.416
A0A5S6PSD7	Bma-mcu-1	A0A5S6PSD7	A0A0H5S397	Bm6438.	BMA-MCU-1.	0.416
A0A5S6PSD7	bma-oxa-1	A0A5S6PSD7	A0A0J9Y5V0	Bm6438.	Bm12987.	0.435
A0A5S6PSG4	A0A5S6PN63	A0A5S6PSG4	A0A5S6PN63	Bm6438.	BMA-MCU-1.	0.416
A0A5S6PSG4	Bma-mcu-1	A0A5S6PSG4	A0A0H5S397	Bm6438.	BMA-MCU-1.	0.416
A0A5S6PSG4	bma-oxa-1	A0A5S6PSG4	A0A0J9Y5V0	Bm6438.	Bm12987.	0.435
Bm1_07760	Bm6179	A0A5S6PND5	A0A0J9XVM0	MICOS complex subunit.	Bm6179.	0.625
Bm4316	bma-mpc-1	A0A0K0JE37	A0A0J9Y1E1	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.889
Bm6179	Bm1_07760	A0A0J9XVM0	A0A5S6PND5	Bm6179.	MICOS complex subunit.	0.625
Bma-mcu-1	A0A5S6PSD7	A0A0H5S397	A0A5S6PSD7	BMA-MCU-1.	Bm6438.	0.416
Bma-mcu-1	A0A5S6PSG4	A0A0H5S397	A0A5S6PSG4	BMA-MCU-1.	Bm6438.	0.416
bma-coq-2	A0A5S6PAY8	A0A1U7F4B8	A0A5S6PAY8	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	Bm13945, isoform c.	0.542
bma-mpc-1	Bm4316	A0A0J9Y1E1	A0A0K0JE37	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.889
bma-mpc-1	bma-mpc-2.1	A0A0J9Y1E1	A0A0J9Y4I5	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.889
bma-mpc-2.1	bma-mpc-1	A0A0J9Y4I5	A0A0J9Y1E1	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.889
bma-oxa-1	A0A5S6PSD7	A0A0J9Y5V0	A0A5S6PSD7	Bm12987.	Bm6438.	0.435
bma-oxa-1	A0A5S6PSG4	A0A0J9Y5V0	A0A5S6PSG4	Bm12987.	Bm6438.	0.435