(40 nodes) Receptor complex network (Brugia malayi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A5S6PU08	Bm6964. (754 aa)
	Bma-ddr-2	BMA-DDR-2. (805 aa)
	Bm1_43305	Bm4469. (642 aa)
	bma-pat-4	BMA-PAT-4. (467 aa)
	Bm8928	Bm8928. (232 aa)
	Bm1_43540	Bm3124. (374 aa)
	bma-sol-2	BMA-SOL-2. (504 aa)
	bma-let-23	Receptor protein-tyrosine kinase. (1277 aa)
	Bma-gbb-2	BMA-GBB-2. (807 aa)
	bma-molo-1	BMA-MOLO-1. (291 aa)
	bma-svh-2	BMA-SVH-2, isoform a; BMA-SVH-2, isoform c; Belongs to the protein kinase superfamily. Tyr protein kinase family. (911 aa)
	Bm1_20780	Integrin beta; Belongs to the integrin beta chain family. (820 aa)
	Bm1_06550	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (524 aa)
	Bma-daf-4	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (653 aa)
	Bma-daf-1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
	Bm1_49775	BMA-AHA-1, isoform y. (471 aa)
	Bma-egl-15	BMA-EGL-15, isoform c; BMA-EGL-15, isoform e; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1417 aa)
	Bm5314	Bm5314, isoform m. (152 aa)
	Bm1_38550	BMA-PLX-1. (1973 aa)
	A0A5S6P909	Receptor protein serine/threonine kinase. (65 aa)
	A0A5S6PF28	Uncharacterized protein. (135 aa)
	A0A5S6PFE0	Uncharacterized protein. (158 aa)
	A0A5S6PGR9	BMA-SOL-1. (699 aa)
	A0A5S6PGS9	BMA-SOL-1. (693 aa)
	A0A5S6PH87	Uncharacterized protein. (219 aa)
	A0A5S6PHB3	Uncharacterized protein. (259 aa)
	A0A5S6PJ25	Uncharacterized protein. (578 aa)
	A0A5S6PJ78	Uncharacterized protein. (609 aa)
	A0A5S6PK67	BMA-DDR-2. (836 aa)
	A0A5S6PK71	BMA-DDR-2. (748 aa)
	A0A5S6PP12	BMA-VAB-1, isoform f. (1126 aa)
	A0A5S6PPD8	Uncharacterized protein. (270 aa)
	A0A5S6PPN7	Bm5314, isoform m. (1291 aa)
	A0A5S6PPY6	Bm5314, isoform m. (1285 aa)
	A0A5S6PQ58	Bm5314, isoform m. (1306 aa)
	A0A5S6PRP2	Bm6151, isoform d. (794 aa)
	A0A5S6PSN6	Bm6554, isoform a. (487 aa)
	A0A5S6PSR0	Bm6554, isoform a. (475 aa)
	A0A5S6PTU5	Bm6964. (756 aa)
	A0A5S6PUN0	BMA-GBB-2. (801 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6P909	Bma-daf-4	A0A5S6P909	A0A1P6BFZ9	Receptor protein serine/threonine kinase.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.873
A0A5S6P909	bma-let-23	A0A5S6P909	A0A0I9N7Q7	Receptor protein serine/threonine kinase.	Receptor protein-tyrosine kinase.	0.407
A0A5S6PFE0	Bm1_20780	A0A5S6PFE0	A0A0K0JT35	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.983
A0A5S6PFE0	bma-pat-4	A0A5S6PFE0	A0A0H5S8R0	Uncharacterized protein.	BMA-PAT-4.	0.597
A0A5S6PGR9	A0A5S6PHB3	A0A5S6PGR9	A0A5S6PHB3	BMA-SOL-1.	Uncharacterized protein.	0.494
A0A5S6PGR9	Bm1_38550	A0A5S6PGR9	A0A1P6C9B5	BMA-SOL-1.	BMA-PLX-1.	0.491
A0A5S6PGR9	bma-sol-2	A0A5S6PGR9	A0A0I9N777	BMA-SOL-1.	BMA-SOL-2.	0.492
A0A5S6PGS9	A0A5S6PHB3	A0A5S6PGS9	A0A5S6PHB3	BMA-SOL-1.	Uncharacterized protein.	0.495
A0A5S6PGS9	Bm1_38550	A0A5S6PGS9	A0A1P6C9B5	BMA-SOL-1.	BMA-PLX-1.	0.491
A0A5S6PGS9	bma-sol-2	A0A5S6PGS9	A0A0I9N777	BMA-SOL-1.	BMA-SOL-2.	0.452
A0A5S6PH87	bma-let-23	A0A5S6PH87	A0A0I9N7Q7	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.440
A0A5S6PHB3	A0A5S6PGR9	A0A5S6PHB3	A0A5S6PGR9	Uncharacterized protein.	BMA-SOL-1.	0.494
A0A5S6PHB3	A0A5S6PGS9	A0A5S6PHB3	A0A5S6PGS9	Uncharacterized protein.	BMA-SOL-1.	0.495
A0A5S6PHB3	bma-let-23	A0A5S6PHB3	A0A0I9N7Q7	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.440
A0A5S6PHB3	bma-sol-2	A0A5S6PHB3	A0A0I9N777	Uncharacterized protein.	BMA-SOL-2.	0.508
A0A5S6PP12	Bm1_20780	A0A5S6PP12	A0A0K0JT35	BMA-VAB-1, isoform f.	Integrin beta; Belongs to the integrin beta chain family.	0.610
A0A5S6PP12	Bm1_38550	A0A5S6PP12	A0A1P6C9B5	BMA-VAB-1, isoform f.	BMA-PLX-1.	0.662
A0A5S6PP12	bma-let-23	A0A5S6PP12	A0A0I9N7Q7	BMA-VAB-1, isoform f.	Receptor protein-tyrosine kinase.	0.462
A0A5S6PPN7	Bm1_20780	A0A5S6PPN7	A0A0K0JT35	Bm5314, isoform m.	Integrin beta; Belongs to the integrin beta chain family.	0.415
A0A5S6PPN7	bma-let-23	A0A5S6PPN7	A0A0I9N7Q7	Bm5314, isoform m.	Receptor protein-tyrosine kinase.	0.946