(29 nodes) Ribosomal protein S5 domain 2-type fold network (Brugia malayi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bma-gfm-1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (743 aa)
	Bm4979	Bm4979. (914 aa)
	bma-lonp-1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (966 aa)
	Bm1_07190	BMA-EXOS-8. (276 aa)
	bma-rps-2.2	Bm10969, isoform a; Bm10969, isoform c; Belongs to the universal ribosomal protein uS5 family. (276 aa)
	bma-rps-2.1	BMA-RPS-2, isoform b; BMA-RPS-2, isoform c; Belongs to the universal ribosomal protein uS5 family. (270 aa)
	bma-mrps-5	BMA-MRPS-5; Belongs to the universal ribosomal protein uS5 family. (430 aa)
	bma-crn-5	BMA-CRN-5, isoform b. (225 aa)
	Bm13990	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (372 aa)
	Bm1_46835	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1570 aa)
	bma-rps-16	BMA-RPS-16; Belongs to the universal ribosomal protein uS9 family. (143 aa)
	Bm1_33025	Bm1855. (752 aa)
	bma-hsp-90	BMA-DAF-21. (717 aa)
	bma-exos-4.1	BMA-EXOS-4.1. (249 aa)
	bma-eef-2	BMA-EEF-2. (852 aa)
	bma-exos-4.2	BMA-EXOS-4.2. (277 aa)
	Bma-pms-2	BMA-PMS-2. (838 aa)
	Bma-exos-7	BMA-EXOS-7. (306 aa)
	bma-impt-1	Bm6736. (264 aa)
	A0A5S6PKQ9	Elongation factor G, mitochondrial. (659 aa)
	Bm1_44960	Bm7784, isoform c; Bm7784, isoform g. (401 aa)
	Bm5217	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1188 aa)
	Bm1_20215	Bm5434. (690 aa)
	Bm1_06100	BMA-PMS-2. (782 aa)
	Bm1_13250	BMA-EXOS-7. (308 aa)
	bma-eftu-2	BMA-EFTU-2. (978 aa)
	Bm1_16455	Uncharacterized protein. (421 aa)
	bma-mvk-1	BMA-MVK-1, isoform c. (563 aa)
	Bm7859	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1528 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PKQ9	Bm1_20215	A0A5S6PKQ9	A0A5S6PQ18	Elongation factor G, mitochondrial.	Bm5434.	0.464
A0A5S6PKQ9	Bm1_33025	A0A5S6PKQ9	A0A0I9R2U8	Elongation factor G, mitochondrial.	Bm1855.	0.649
A0A5S6PKQ9	Bm1_44960	A0A5S6PKQ9	A0A1P6CD55	Elongation factor G, mitochondrial.	Bm7784, isoform c; Bm7784, isoform g.	0.898
A0A5S6PKQ9	bma-mrps-5	A0A5S6PKQ9	A0A0J9Y138	Elongation factor G, mitochondrial.	BMA-MRPS-5; Belongs to the universal ribosomal protein uS5 family.	0.796
A0A5S6PKQ9	bma-rps-16	A0A5S6PKQ9	A0A0J9XMG4	Elongation factor G, mitochondrial.	BMA-RPS-16; Belongs to the universal ribosomal protein uS9 family.	0.790
A0A5S6PKQ9	bma-rps-2.1	A0A5S6PKQ9	A0A0J9Y3C2	Elongation factor G, mitochondrial.	BMA-RPS-2, isoform b; BMA-RPS-2, isoform c; Belongs to the universal ribosomal protein uS5 family.	0.915
A0A5S6PKQ9	bma-rps-2.2	A0A5S6PKQ9	A0A0K0IQ58	Elongation factor G, mitochondrial.	Bm10969, isoform a; Bm10969, isoform c; Belongs to the universal ribosomal protein uS5 family.	0.827
Bm13990	bma-mvk-1	A0A0J9XY66	A0A158Q108	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	BMA-MVK-1, isoform c.	0.994
Bm1_06100	Bm1_44960	A0A5S6PMW4	A0A1P6CD55	BMA-PMS-2.	Bm7784, isoform c; Bm7784, isoform g.	0.432
Bm1_07190	Bm1_13250	A0A0K0IQL3	A0A5S6PL90	BMA-EXOS-8.	BMA-EXOS-7.	0.975
Bm1_07190	Bm1_33025	A0A0K0IQL3	A0A0I9R2U8	BMA-EXOS-8.	Bm1855.	0.461
Bm1_07190	Bma-exos-7	A0A0K0IQL3	A0A0H5S0J8	BMA-EXOS-8.	BMA-EXOS-7.	0.975
Bm1_07190	bma-crn-5	A0A0K0IQL3	A0A0J9XYP4	BMA-EXOS-8.	BMA-CRN-5, isoform b.	0.999
Bm1_07190	bma-exos-4.1	A0A0K0IQL3	A0A0H5S6Q3	BMA-EXOS-8.	BMA-EXOS-4.1.	0.947
Bm1_07190	bma-exos-4.2	A0A0K0IQL3	A0A0K0JMI7	BMA-EXOS-8.	BMA-EXOS-4.2.	0.957
Bm1_13250	Bm1_07190	A0A5S6PL90	A0A0K0IQL3	BMA-EXOS-7.	BMA-EXOS-8.	0.975
Bm1_13250	bma-crn-5	A0A5S6PL90	A0A0J9XYP4	BMA-EXOS-7.	BMA-CRN-5, isoform b.	0.986
Bm1_13250	bma-exos-4.1	A0A5S6PL90	A0A0H5S6Q3	BMA-EXOS-7.	BMA-EXOS-4.1.	0.922
Bm1_13250	bma-exos-4.2	A0A5S6PL90	A0A0K0JMI7	BMA-EXOS-7.	BMA-EXOS-4.2.	0.979
Bm1_13250	bma-rps-16	A0A5S6PL90	A0A0J9XMG4	BMA-EXOS-7.	BMA-RPS-16; Belongs to the universal ribosomal protein uS9 family.	0.411