27 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bm1_49130	Bm3810, isoform h; Bm3810, isoform i. (794 aa)
	A0A5S6PJF2	Uncharacterized protein. (581 aa)
	A0A5S6PJ23	Uncharacterized protein. (395 aa)
	A0A5S6PI49	Bm2589. (1354 aa)
	A0A5S6PI12	Bm2589. (1195 aa)
	A0A5S6PG98	BMA-TIAR-3. (170 aa)
	A0A5S6PDV1	Uncharacterized protein. (249 aa)
	Bm1_54210	Uncharacterized protein. (128 aa)
	Bm1_52995	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	Bma-mnk-1	BMA-MNK-1, isoform u; BMA-MNK-1, isoform v. (783 aa)
	Bma-egl-15	BMA-EGL-15, isoform c; BMA-EGL-15, isoform e; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1417 aa)
	Bm3810	Bm3810, isoform h; Bm3810, isoform i. (173 aa)
	Bma-ubq-1	BMA-UBQ-1, isoform a; BMA-UBQ-1, isoform e. (372 aa)
	Bm2341	Bm2341, isoform c. (942 aa)
	Bm1_34045	Serine/threonine-protein phosphatase. (323 aa)
	bma-rpb-7	BMA-RPB-7. (174 aa)
	bma-rpb-12	BMA-RPB-12. (63 aa)
	bma-rpb-2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1171 aa)
	Bm1_04590	Bm2355. (509 aa)
	Bma-tiar-3	BMA-TIAR-3. (315 aa)
	bma-let-60	BMA-LET-60. (183 aa)
	Bm1_26995	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	bma-rpb-5	BMA-RPB-5. (211 aa)
	bma-rpb-6	BMA-RPB-6, isoform a; BMA-RPB-6, isoform b. (174 aa)
	bma-gtf-2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (294 aa)
	bma-let-92.2	Serine/threonine-protein phosphatase. (323 aa)
	bma-ama-1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1870 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PDV1	Bm1_04590	A0A5S6PDV1	A0A0K0J5K4	Uncharacterized protein.	Bm2355.	0.537
A0A5S6PDV1	Bm1_52995	A0A5S6PDV1	A0A1P6CBC0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.592
A0A5S6PDV1	bma-ama-1	A0A5S6PDV1	A0A0H5S9G0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.485
A0A5S6PDV1	bma-gtf-2f2	A0A5S6PDV1	A0A0J9XN99	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.565
A0A5S6PDV1	bma-rpb-5	A0A5S6PDV1	A0A0K0J005	Uncharacterized protein.	BMA-RPB-5.	0.591
A0A5S6PDV1	bma-rpb-7	A0A5S6PDV1	A0A0K0JPP7	Uncharacterized protein.	BMA-RPB-7.	0.577
A0A5S6PG98	Bm1_26995	A0A5S6PG98	A0A0K0J039	BMA-TIAR-3.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.474
A0A5S6PG98	Bm1_49130	A0A5S6PG98	A0A5S6PL16	BMA-TIAR-3.	Bm3810, isoform h; Bm3810, isoform i.	0.569
A0A5S6PG98	Bm3810	A0A5S6PG98	A0A1P6BZX3	BMA-TIAR-3.	Bm3810, isoform h; Bm3810, isoform i.	0.569
A0A5S6PG98	bma-rpb-12	A0A5S6PG98	A0A0K0JAQ0	BMA-TIAR-3.	BMA-RPB-12.	0.491
A0A5S6PG98	bma-rpb-2	A0A5S6PG98	A0A0K0J5T8	BMA-TIAR-3.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.441
A0A5S6PG98	bma-rpb-5	A0A5S6PG98	A0A0K0J005	BMA-TIAR-3.	BMA-RPB-5.	0.460
A0A5S6PG98	bma-rpb-6	A0A5S6PG98	A0A0J9Y562	BMA-TIAR-3.	BMA-RPB-6, isoform a; BMA-RPB-6, isoform b.	0.476
A0A5S6PG98	bma-rpb-7	A0A5S6PG98	A0A0K0JPP7	BMA-TIAR-3.	BMA-RPB-7.	0.449
A0A5S6PI12	Bma-ubq-1	A0A5S6PI12	A0A1P6BY67	Bm2589.	BMA-UBQ-1, isoform a; BMA-UBQ-1, isoform e.	0.422
A0A5S6PI49	Bma-ubq-1	A0A5S6PI49	A0A1P6BY67	Bm2589.	BMA-UBQ-1, isoform a; BMA-UBQ-1, isoform e.	0.422
A0A5S6PJ23	Bm1_04590	A0A5S6PJ23	A0A0K0J5K4	Uncharacterized protein.	Bm2355.	0.537
A0A5S6PJ23	Bm1_52995	A0A5S6PJ23	A0A1P6CBC0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.592
A0A5S6PJ23	bma-ama-1	A0A5S6PJ23	A0A0H5S9G0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.485
A0A5S6PJ23	bma-gtf-2f2	A0A5S6PJ23	A0A0J9XN99	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.565