33 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bma-npp-12	BMA-NPP-12. (1845 aa)
	bma-ama-1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1870 aa)
	bma-npp-3	Bm5020. (1631 aa)
	bma-npp-2	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (614 aa)
	Bma-his-56	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	bma-npp-1	BMA-NPP-1. (492 aa)
	bma-npp-22	Bm10452. (564 aa)
	bma-npp-10.2	Bm14685, isoform a. (363 aa)
	bma-npp-10.1	BMA-NPP-10. (1294 aa)
	bma-npp-18	BMA-NPP-18; Belongs to the WD repeat SEC13 family. (374 aa)
	bma-rpb-5	BMA-RPB-5. (211 aa)
	Bm1_26995	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	bma-rpb-2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1171 aa)
	Bm2874	Histone H2B; Belongs to the histone H2B family. (224 aa)
	bma-rpb-12	BMA-RPB-12. (63 aa)
	bma-htz-1	Histone H2A; Belongs to the histone H2A family. (136 aa)
	Bm1_17225	Nuclear pore protein. (781 aa)
	Bma-npp-8	BMA-NPP-8. (1335 aa)
	bma-rpb-7	BMA-RPB-7. (174 aa)
	bma-npp-16	BMA-NPP-16. (472 aa)
	Bm8720	Histone H2B; Belongs to the histone H2B family. (132 aa)
	bma-npp-5	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (777 aa)
	Bm1_41450	Bm9873. (348 aa)
	Bm1_36125	Bm11157; Bm3286. (371 aa)
	Bm4113	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	Bma-npp-19	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (333 aa)
	Bm1_52995	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	A0A5S6PRG6	Bm5831, isoform c. (1034 aa)
	A0A5S6PSM4	BMA-NPP-8. (1318 aa)
	A0A5S6PVC2	Uncharacterized protein. (588 aa)
	A0A5S6PVF9	Uncharacterized protein. (565 aa)
	A0A5S6PWS0	BMA-NPP-4, isoform b. (523 aa)
	Bm1_44725	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). (215 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PRG6	A0A5S6PSM4	A0A5S6PRG6	A0A5S6PSM4	Bm5831, isoform c.	BMA-NPP-8.	0.902
A0A5S6PRG6	A0A5S6PVC2	A0A5S6PRG6	A0A5S6PVC2	Bm5831, isoform c.	Uncharacterized protein.	0.771
A0A5S6PRG6	A0A5S6PVF9	A0A5S6PRG6	A0A5S6PVF9	Bm5831, isoform c.	Uncharacterized protein.	0.771
A0A5S6PRG6	A0A5S6PWS0	A0A5S6PRG6	A0A5S6PWS0	Bm5831, isoform c.	BMA-NPP-4, isoform b.	0.782
A0A5S6PRG6	Bm1_17225	A0A5S6PRG6	A0A0K0JN01	Bm5831, isoform c.	Nuclear pore protein.	0.983
A0A5S6PRG6	Bm1_36125	A0A5S6PRG6	A0A1P6BIN2	Bm5831, isoform c.	Bm11157; Bm3286.	0.918
A0A5S6PRG6	Bm1_41450	A0A5S6PRG6	A0A0K0K0T1	Bm5831, isoform c.	Bm9873.	0.919
A0A5S6PRG6	Bm1_44725	A0A5S6PRG6	P38542	Bm5831, isoform c.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity).	0.980
A0A5S6PRG6	Bma-npp-19	A0A5S6PRG6	A0A1P6C4S5	Bm5831, isoform c.	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	0.924
A0A5S6PRG6	Bma-npp-8	A0A5S6PRG6	A0A0K0JNH1	Bm5831, isoform c.	BMA-NPP-8.	0.902
A0A5S6PRG6	bma-npp-1	A0A5S6PRG6	A0A0J9XR36	Bm5831, isoform c.	BMA-NPP-1.	0.972
A0A5S6PRG6	bma-npp-10.1	A0A5S6PRG6	A0A0J9Y147	Bm5831, isoform c.	BMA-NPP-10.	0.922
A0A5S6PRG6	bma-npp-10.2	A0A5S6PRG6	A0A0J9Y0Z1	Bm5831, isoform c.	Bm14685, isoform a.	0.922
A0A5S6PRG6	bma-npp-12	A0A5S6PRG6	A0A0H5S8B8	Bm5831, isoform c.	BMA-NPP-12.	0.902
A0A5S6PRG6	bma-npp-16	A0A5S6PRG6	A0A0K0JQ02	Bm5831, isoform c.	BMA-NPP-16.	0.990
A0A5S6PRG6	bma-npp-18	A0A5S6PRG6	A0A0J9YB15	Bm5831, isoform c.	BMA-NPP-18; Belongs to the WD repeat SEC13 family.	0.913
A0A5S6PRG6	bma-npp-2	A0A5S6PRG6	A0A0I9N9P6	Bm5831, isoform c.	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).	0.978
A0A5S6PRG6	bma-npp-22	A0A5S6PRG6	A0A0J9XYU2	Bm5831, isoform c.	Bm10452.	0.825
A0A5S6PRG6	bma-npp-3	A0A5S6PRG6	A0A0I9N5P9	Bm5831, isoform c.	Bm5020.	0.979
A0A5S6PRG6	bma-npp-5	A0A5S6PRG6	A0A0K0JX13	Bm5831, isoform c.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.990