30 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bma-gtf-2h3	Bm7634, isoform b; Bm7634, isoform c. (274 aa)
	bma-cdk-9	BMA-CDK-9; Belongs to the protein kinase superfamily. (424 aa)
	bma-ama-1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1870 aa)
	Bm1_39230	Bm10999. (609 aa)
	bma-cyh-1	BMA-CYH-1. (320 aa)
	bma-fcp-1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (576 aa)
	Bm7120	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (483 aa)
	bma-gtf-2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (294 aa)
	bma-tceb-3	Bm9930. (461 aa)
	bma-xpb-1	Bm13812, isoform a; Bm13812, isoform b. (798 aa)
	bma-spt-4	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (119 aa)
	bma-rpb-6	BMA-RPB-6, isoform a; BMA-RPB-6, isoform b. (174 aa)
	bma-gtf-2h2c	General transcription factor IIH subunit. (382 aa)
	bma-rpb-5	BMA-RPB-5. (211 aa)
	Bm1_26995	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	bma-rpb-2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1171 aa)
	bma-rpb-12	BMA-RPB-12. (63 aa)
	bma-rpb-7	BMA-RPB-7. (174 aa)
	Bm8628	Bm8628. (543 aa)
	Bm1_17615	Bm5993, isoform b. (305 aa)
	Bm1_52995	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	bma-cdk-12	BMA-CDTL-7. (995 aa)
	Bm1_22590	Uncharacterized protein. (670 aa)
	A0A5S6PCR4	Uncharacterized protein. (93 aa)
	A0A5S6PDE4	Uncharacterized protein. (105 aa)
	Bm1_50345	BMA-CCNK-1. (245 aa)
	Bm1_34795	Bm5177, isoform a. (608 aa)
	A0A5S6PTZ8	Bm6839, isoform b. (79 aa)
	A0A5S6PWZ0	Bm8628. (473 aa)
	Bm1_10890	Immunodominant antigen homologue, putative. (798 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6PCR4	A0A5S6PDE4	A0A5S6PCR4	A0A5S6PDE4	Uncharacterized protein.	Uncharacterized protein.	0.769
A0A5S6PCR4	A0A5S6PTZ8	A0A5S6PCR4	A0A5S6PTZ8	Uncharacterized protein.	Bm6839, isoform b.	0.862
A0A5S6PCR4	Bm1_17615	A0A5S6PCR4	A0A1P6C6E2	Uncharacterized protein.	Bm5993, isoform b.	0.607
A0A5S6PCR4	Bm1_26995	A0A5S6PCR4	A0A0K0J039	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.915
A0A5S6PCR4	Bm1_52995	A0A5S6PCR4	A0A1P6CBC0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.914
A0A5S6PCR4	Bm7120	A0A5S6PCR4	A0A0H5SQX9	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.970
A0A5S6PCR4	bma-ama-1	A0A5S6PCR4	A0A0H5S9G0	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.948
A0A5S6PCR4	bma-cyh-1	A0A5S6PCR4	A0A0H5SDL0	Uncharacterized protein.	BMA-CYH-1.	0.965
A0A5S6PCR4	bma-gtf-2f2	A0A5S6PCR4	A0A0J9XN99	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.923
A0A5S6PCR4	bma-gtf-2h2c	A0A5S6PCR4	A0A0K0IZU1	Uncharacterized protein.	General transcription factor IIH subunit.	0.970
A0A5S6PCR4	bma-gtf-2h3	A0A5S6PCR4	A0A0J9XZK0	Uncharacterized protein.	Bm7634, isoform b; Bm7634, isoform c.	0.970
A0A5S6PCR4	bma-rpb-12	A0A5S6PCR4	A0A0K0JAQ0	Uncharacterized protein.	BMA-RPB-12.	0.914
A0A5S6PCR4	bma-rpb-2	A0A5S6PCR4	A0A0K0J5T8	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.914
A0A5S6PCR4	bma-rpb-5	A0A5S6PCR4	A0A0K0J005	Uncharacterized protein.	BMA-RPB-5.	0.914
A0A5S6PCR4	bma-rpb-6	A0A5S6PCR4	A0A0J9Y562	Uncharacterized protein.	BMA-RPB-6, isoform a; BMA-RPB-6, isoform b.	0.935
A0A5S6PCR4	bma-rpb-7	A0A5S6PCR4	A0A0K0JPP7	Uncharacterized protein.	BMA-RPB-7.	0.913
A0A5S6PCR4	bma-xpb-1	A0A5S6PCR4	A0A0J9XW60	Uncharacterized protein.	Bm13812, isoform a; Bm13812, isoform b.	0.972
A0A5S6PDE4	A0A5S6PCR4	A0A5S6PDE4	A0A5S6PCR4	Uncharacterized protein.	Uncharacterized protein.	0.769
A0A5S6PDE4	A0A5S6PWZ0	A0A5S6PDE4	A0A5S6PWZ0	Uncharacterized protein.	Bm8628.	0.568
A0A5S6PDE4	Bm1_10890	A0A5S6PDE4	A0A5S6PXE2	Uncharacterized protein.	Immunodominant antigen homologue, putative.	0.418