84 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bm1_31220	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (849 aa)
	bma-aldo-2	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (382 aa)
	bma-rib-1	BMA-RIB-1; Belongs to the glycosyltransferase 47 family. (670 aa)
	bma-pgk-1	Phosphoglycerate kinase. (415 aa)
	Bm1_12675	Bm9138. (58 aa)
	bma-fbp-1	BMA-FBP-1; Belongs to the FBPase class 1 family. (355 aa)
	bma-aldo-1	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	Bm1_30540	Alpha-mannosidase; Bm9778. (1049 aa)
	bma-sqv-8	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (345 aa)
	Bm4461	Bm4461. (297 aa)
	Bm1_09205	Bm6148. (584 aa)
	bma-got-1.2	Aspartate aminotransferase. (401 aa)
	Bm3204	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (237 aa)
	bma-hst-2	BMA-HST-2. (335 aa)
	bma-misc-1	BMA-MISC-1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
	bma-hst-3.1	BMA-HST-3.1. (337 aa)
	Bm1_27085	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (335 aa)
	Bm5729	Bm5729. (492 aa)
	bma-hxk-1.1	Phosphotransferase. (450 aa)
	Bm1_23965	Bm13760; Belongs to the mitochondrial carrier (TC 2.A.29) family. (319 aa)
	Bm1704	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (427 aa)
	bma-rpia-1	BMA-RPIA-1, isoform c. (260 aa)
	Bm1_41940	Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
	Bm594	Bm594, isoform h; Bm594, isoform j. (315 aa)
	bma-tpi-1	Triosephosphate isomerase. (247 aa)
	Bm6539	Bm6539; Belongs to the phosphohexose mutase family. (586 aa)
	Bm1_53055	Bm10026. (377 aa)
	Bm1_10280	BMA-TKT-1; Transketolase. (622 aa)
	Bm1_36755	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (540 aa)
	bma-tald-1	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (322 aa)
	Bm1_45340	Bm2542. (900 aa)
	Bm1_55785	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (347 aa)
	Bm4678	Hexokinase; Active against glucose, fructose, mannose, maltose and galactose. (572 aa)
	Bma-sul-1	BMA-SUL-1. (819 aa)
	bma-slc-25a10	Bm5009; Belongs to the mitochondrial carrier (TC 2.A.29) family. (305 aa)
	Bm1_50545	BMA-PST-1. (410 aa)
	Bm5204	Bm5204. (347 aa)
	bma-pygl-1	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa)
	Bma-chs-1	BMA-CHS-1. (1321 aa)
	bma-pck-1	BMA-PCK-1, isoform b. (373 aa)
	Bm1_14855	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (420 aa)
	Bm7089	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (784 aa)
	Bm7565	Bm7565. (191 aa)
	Bm13963	UTP--glucose-1-phosphate uridylyltransferase. (499 aa)
	Bm14017	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (252 aa)
	A0A5S6P7D1	Uncharacterized protein. (80 aa)
	A0A5S6P7D5	Uncharacterized protein. (94 aa)
	Bm1_16455	Uncharacterized protein. (421 aa)
	Bm1_15740	Bm13746, isoform a. (571 aa)
	A0A5S6PB14	6-phosphogluconate dehydrogenase, decarboxylating. (489 aa)
	A0A5S6PBY5	Uncharacterized protein. (449 aa)
	A0A5S6PC44	Uncharacterized protein. (456 aa)
	A0A5S6PFC1	Phosphotransferase. (451 aa)
	A0A5S6PFE9	Ribokinase. (307 aa)
	A0A5S6PFN2	Bm13849. (318 aa)
	A0A5S6PFZ0	Uncharacterized protein. (114 aa)
	A0A5S6PGV0	Bm2166. (471 aa)
	A0A5S6PGX3	Bm2166. (344 aa)
	A0A5S6PIQ6	Bm2865. (450 aa)
	A0A5S6PIW5	Bm2865. (495 aa)
	Bm1_16595	Bm3223, isoform b. (239 aa)
	A0A5S6PJX5	Uncharacterized protein. (291 aa)
	A0A5S6PJX8	Uncharacterized protein. (230 aa)
	A0A5S6PKC0	Uncharacterized protein. (232 aa)
	A0A5S6PKC2	Uncharacterized protein. (275 aa)
	A0A5S6PKT0	BMA-EKL-1, isoform d. (577 aa)
	A0A5S6PMM1	BMA-PST-2. (345 aa)
	A0A5S6PMT6	BMA-PST-2. (369 aa)
	A0A5S6PMZ5	Hexokinase. (572 aa)
	A0A5S6PNQ9	BMA-SUL-1. (825 aa)
	A0A5S6PNZ6	Uncharacterized protein. (376 aa)
	Bm1_13990	Uncharacterized protein. (383 aa)
	A0A5S6PP79	Hexosyltransferase. (773 aa)
	A0A5S6PPB4	Bm5204. (164 aa)
	A0A5S6PPQ5	Hexosyltransferase. (681 aa)
	Bm1_35215	BMA-CHS-1. (1316 aa)
	Bm1_19700	Hexosyltransferase. (730 aa)
	A0A5S6PTR8	Phosphorylase b kinase regulatory subunit. (1154 aa)
	A0A5S6PTX3	Phosphorylase b kinase regulatory subunit. (1146 aa)
	A0A5S6PU38	Phosphorylase b kinase regulatory subunit. (1145 aa)
	A0A5S6PUD3	Phosphorylase b kinase regulatory subunit. (1137 aa)
	A0A5S6PY04	Chitin synthase 2. (1717 aa)
	A0A5S6PYP1	Chitin synthase 2. (1698 aa)
	G3PD	Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6P7D1	A0A5S6PB14	A0A5S6P7D1	A0A5S6PB14	Uncharacterized protein.	6-phosphogluconate dehydrogenase, decarboxylating.	0.767
A0A5S6P7D1	A0A5S6PBY5	A0A5S6P7D1	A0A5S6PBY5	Uncharacterized protein.	Uncharacterized protein.	0.434
A0A5S6P7D1	A0A5S6PC44	A0A5S6P7D1	A0A5S6PC44	Uncharacterized protein.	Uncharacterized protein.	0.434
A0A5S6P7D1	A0A5S6PFE9	A0A5S6P7D1	A0A5S6PFE9	Uncharacterized protein.	Ribokinase.	0.415
A0A5S6P7D1	A0A5S6PFN2	A0A5S6P7D1	A0A5S6PFN2	Uncharacterized protein.	Bm13849.	0.424
A0A5S6P7D1	A0A5S6PFZ0	A0A5S6P7D1	A0A5S6PFZ0	Uncharacterized protein.	Uncharacterized protein.	0.718
A0A5S6P7D1	A0A5S6PGV0	A0A5S6P7D1	A0A5S6PGV0	Uncharacterized protein.	Bm2166.	0.690
A0A5S6P7D1	A0A5S6PGX3	A0A5S6P7D1	A0A5S6PGX3	Uncharacterized protein.	Bm2166.	0.690
A0A5S6P7D1	Bm13963	A0A5S6P7D1	A0A1P6BMH5	Uncharacterized protein.	UTP--glucose-1-phosphate uridylyltransferase.	0.418
A0A5S6P7D1	Bm14017	A0A5S6P7D1	A0A1U7F107	Uncharacterized protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.505
A0A5S6P7D1	Bm1704	A0A5S6P7D1	A0A0J9XKM7	Uncharacterized protein.	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.	0.563
A0A5S6P7D1	Bm1_10280	A0A5S6P7D1	A0A0K0IYT1	Uncharacterized protein.	BMA-TKT-1; Transketolase.	0.791
A0A5S6P7D1	Bm1_15740	A0A5S6P7D1	A0A5S6PAF8	Uncharacterized protein.	Bm13746, isoform a.	0.790
A0A5S6P7D1	Bm1_16455	A0A5S6P7D1	A0A5S6P908	Uncharacterized protein.	Uncharacterized protein.	0.422
A0A5S6P7D1	Bm1_27085	A0A5S6P7D1	A0A0H5SQ52	Uncharacterized protein.	Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.	0.513
A0A5S6P7D1	Bm1_31220	A0A5S6P7D1	A0A0H5S2N9	Uncharacterized protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.855
A0A5S6P7D1	Bm1_36755	A0A5S6P7D1	A0A0K0IYU1	Uncharacterized protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.501
A0A5S6P7D1	Bm1_41940	A0A5S6P7D1	A0A0J9XXG7	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.889
A0A5S6P7D1	Bm3204	A0A5S6P7D1	A0A0H5SHF9	Uncharacterized protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.564
A0A5S6P7D1	Bm6539	A0A5S6P7D1	A0A0J9YAB6	Uncharacterized protein.	Bm6539; Belongs to the phosphohexose mutase family.	0.514