30 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bm1_34795	Bm5177, isoform a. (608 aa)
	bma-ama-1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1870 aa)
	bma-taf-10	BMA-TAF-10. (163 aa)
	bma-cyh-1	BMA-CYH-1. (320 aa)
	Bm7120	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (483 aa)
	bma-gtf-2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (294 aa)
	bma-taf-13	BMA-TAF-13. (121 aa)
	A0A5S6PTZ8	Bm6839, isoform b. (79 aa)
	bma-xpb-1	Bm13812, isoform a; Bm13812, isoform b. (798 aa)
	bma-gtf-2h3	Bm7634, isoform b; Bm7634, isoform c. (274 aa)
	bma-tbp-1	BMA-TBP-1, isoform b. (347 aa)
	bma-rpb-6	BMA-RPB-6, isoform a; BMA-RPB-6, isoform b. (174 aa)
	bma-gtf-2h2c	General transcription factor IIH subunit. (382 aa)
	bma-rpb-5	BMA-RPB-5. (211 aa)
	Bm1_26995	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (149 aa)
	Bm14072	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	bma-taf-12	Bm14701. (257 aa)
	bma-rpb-2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1171 aa)
	bma-rpb-12	BMA-RPB-12. (63 aa)
	bma-taf-9	BMA-TAF-9. (172 aa)
	bma-rpb-7	BMA-RPB-7. (174 aa)
	Bm7291	Bm7291. (242 aa)
	Bm1_21240	BMA-TAF-12, isoform b. (420 aa)
	Bm1_52995	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
	bma-pqn-51	BMA-PQN-51, isoform a; BMA-PQN-51, isoform b. (405 aa)
	A0A5S6P8L1	Bm6177, isoform f. (1819 aa)
	A0A5S6P8N4	Bm6177, isoform f. (1815 aa)
	A0A5S6PCR4	Uncharacterized protein. (93 aa)
	Bm1_47705	Uncharacterized protein. (616 aa)
	Bm1_04690	Bm4201, isoform b. (295 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6P8L1	A0A5S6PCR4	A0A5S6P8L1	A0A5S6PCR4	Bm6177, isoform f.	Uncharacterized protein.	0.639
A0A5S6P8L1	Bm14072	A0A5S6P8L1	A0A0K0J061	Bm6177, isoform f.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.837
A0A5S6P8L1	Bm1_04690	A0A5S6P8L1	A0A0J9YAL2	Bm6177, isoform f.	Bm4201, isoform b.	0.978
A0A5S6P8L1	Bm1_21240	A0A5S6P8L1	A0A1P6BG08	Bm6177, isoform f.	BMA-TAF-12, isoform b.	0.978
A0A5S6P8L1	Bm1_26995	A0A5S6P8L1	A0A0K0J039	Bm6177, isoform f.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.753
A0A5S6P8L1	Bm1_34795	A0A5S6P8L1	A0A5S6PPR5	Bm6177, isoform f.	Bm5177, isoform a.	0.639
A0A5S6P8L1	Bm1_47705	A0A5S6P8L1	A0A5S6PKS9	Bm6177, isoform f.	Uncharacterized protein.	0.970
A0A5S6P8L1	Bm1_52995	A0A5S6P8L1	A0A1P6CBC0	Bm6177, isoform f.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.752
A0A5S6P8L1	Bm7120	A0A5S6P8L1	A0A0H5SQX9	Bm6177, isoform f.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.745
A0A5S6P8L1	Bm7291	A0A5S6P8L1	A0A0K0JRQ6	Bm6177, isoform f.	Bm7291.	0.980
A0A5S6P8L1	bma-ama-1	A0A5S6P8L1	A0A0H5S9G0	Bm6177, isoform f.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.847
A0A5S6P8L1	bma-cyh-1	A0A5S6P8L1	A0A0H5SDL0	Bm6177, isoform f.	BMA-CYH-1.	0.748
A0A5S6P8L1	bma-gtf-2f2	A0A5S6P8L1	A0A0J9XN99	Bm6177, isoform f.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.776
A0A5S6P8L1	bma-gtf-2h2c	A0A5S6P8L1	A0A0K0IZU1	Bm6177, isoform f.	General transcription factor IIH subunit.	0.737
A0A5S6P8L1	bma-gtf-2h3	A0A5S6P8L1	A0A0J9XZK0	Bm6177, isoform f.	Bm7634, isoform b; Bm7634, isoform c.	0.767
A0A5S6P8L1	bma-pqn-51	A0A5S6P8L1	A0A1U7F2W6	Bm6177, isoform f.	BMA-PQN-51, isoform a; BMA-PQN-51, isoform b.	0.784
A0A5S6P8L1	bma-rpb-12	A0A5S6P8L1	A0A0K0JAQ0	Bm6177, isoform f.	BMA-RPB-12.	0.752
A0A5S6P8L1	bma-rpb-2	A0A5S6P8L1	A0A0K0J5T8	Bm6177, isoform f.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.790
A0A5S6P8L1	bma-rpb-5	A0A5S6P8L1	A0A0K0J005	Bm6177, isoform f.	BMA-RPB-5.	0.783
A0A5S6P8L1	bma-rpb-6	A0A5S6P8L1	A0A0J9Y562	Bm6177, isoform f.	BMA-RPB-6, isoform a; BMA-RPB-6, isoform b.	0.756