46 items (Brugia malayi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bma-ras-2	BMA-RAS-2. (212 aa)
	bma-pik-1	BMA-PIK-1; Belongs to the protein kinase superfamily. (470 aa)
	Bm1_11350	Bm5676. (487 aa)
	bma-ccb-1	BMA-CCB-1. (528 aa)
	bma-coa-3	Bm3837. (139 aa)
	bma-fln-2	BMA-FLN-2, isoform a; BMA-FLN-2, isoform c. (3006 aa)
	Bma-gpa-12	BMA-GPA-12. (361 aa)
	Bm1_40440	Bm10945. (393 aa)
	Bma-egl-17	BMA-EGL-17; Belongs to the heparin-binding growth factors family. (215 aa)
	bma-sek-1	BMA-SEK-1, isoform a; Belongs to the protein kinase superfamily. (382 aa)
	Bm1_26085	Bm10748; Belongs to the protein kinase superfamily. (392 aa)
	bma-hsp-1	BMA-HSP-1; Belongs to the heat shock protein 70 family. (645 aa)
	bma-pph-5	BMA-PPH-5. (492 aa)
	bma-mpk-1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (385 aa)
	bma-let-23	Receptor protein-tyrosine kinase. (1277 aa)
	bma-tax-6	Serine/threonine-protein phosphatase. (530 aa)
	bma-lit-1	Mitogen-activated protein kinase. (331 aa)
	bma-pmk-3	BMA-PMK-3, isoform c. (293 aa)
	bma-mxl-1	BMA-MXL-1. (168 aa)
	Bm1_50730	Bm10547. (122 aa)
	bma-let-60	BMA-LET-60. (183 aa)
	Bm1_31785	Mitogen-activated protein kinase. (369 aa)
	Bm1_25835	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (383 aa)
	Bm2115	Bm2115. (192 aa)
	Bm1_39445	BMA-RAP-1. (186 aa)
	bma-mig-2	BMA-MIG-2. (195 aa)
	bma-rskn-2	Ribosomal protein S6 kinase. (785 aa)
	Bm1_32140	Bm3378, isoform a; Bm3378, isoform b. (544 aa)
	bma-svh-2	BMA-SVH-2, isoform a; BMA-SVH-2, isoform c; Belongs to the protein kinase superfamily. Tyr protein kinase family. (911 aa)
	bma-ced-2	BMA-CED-2, isoform a; BMA-CED-2, isoform b. (288 aa)
	Bm1_48560	BMA-MEK-2; Belongs to the protein kinase superfamily. (389 aa)
	bma-lin-45	BMA-LIN-45, isoform a; BMA-LIN-45, isoform b. (755 aa)
	Bm1_54585	BMA-SEK-3; Belongs to the protein kinase superfamily. (362 aa)
	bma-cdc-42	Bm5286, isoform a; Bm5286, isoform a; Bm5287, isoform a; Bm5287, isoform a. (191 aa)
	Bma-mnk-1	BMA-MNK-1, isoform u; BMA-MNK-1, isoform v. (783 aa)
	Bma-jun-1	BMA-JUN-1, isoform a; BMA-JUN-1, isoform f. (366 aa)
	Bm6990	Bm6990. (2187 aa)
	bma-ras-1	BMA-RAS-1, isoform a; BMA-RAS-1, isoform b. (209 aa)
	bma-ppm-1.a	BMA-PPM-1. (395 aa)
	A0A5S6P909	Receptor protein serine/threonine kinase. (65 aa)
	Bm1_39550	Voltage-dependent L-type calcium channel subunit alpha. (1886 aa)
	Bm1_33905	BMA-ARR-1, isoform c. (423 aa)
	A0A5S6PPN7	Bm5314, isoform m. (1291 aa)
	Bm1_36455	BMA-PXF-1, isoform e. (1432 aa)
	A0A5S6PTQ4	Uncharacterized protein. (1724 aa)
	Bm1_31755	Uncharacterized protein. (600 aa)

Your Current Organism:

Brugia malayi

NCBI taxonomy Id: 6279
Other names: B. malayi, agent of lymphatic filariasis

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5S6P909	Bm1_48560	A0A5S6P909	A0A0K0JPN5	Receptor protein serine/threonine kinase.	BMA-MEK-2; Belongs to the protein kinase superfamily.	0.403
A0A5S6P909	bma-let-23	A0A5S6P909	A0A0I9N7Q7	Receptor protein serine/threonine kinase.	Receptor protein-tyrosine kinase.	0.407
A0A5S6PPN7	Bma-egl-17	A0A5S6PPN7	A0A0H5SBX0	Bm5314, isoform m.	BMA-EGL-17; Belongs to the heparin-binding growth factors family.	0.964
A0A5S6PPN7	bma-ced-2	A0A5S6PPN7	A0A0K0JNG9	Bm5314, isoform m.	BMA-CED-2, isoform a; BMA-CED-2, isoform b.	0.525
A0A5S6PPN7	bma-let-23	A0A5S6PPN7	A0A0I9N7Q7	Bm5314, isoform m.	Receptor protein-tyrosine kinase.	0.946
A0A5S6PPN7	bma-let-60	A0A5S6PPN7	A0A0K0J2J0	Bm5314, isoform m.	BMA-LET-60.	0.441
A0A5S6PPN7	bma-svh-2	A0A5S6PPN7	A0A0K0JKD3	Bm5314, isoform m.	BMA-SVH-2, isoform a; BMA-SVH-2, isoform c; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.917
A0A5S6PTQ4	Bm1_54585	A0A5S6PTQ4	A0A0K0JYZ3	Uncharacterized protein.	BMA-SEK-3; Belongs to the protein kinase superfamily.	0.910
A0A5S6PTQ4	Bm6990	A0A5S6PTQ4	A0A1U7F3R9	Uncharacterized protein.	Bm6990.	0.902
A0A5S6PTQ4	bma-fln-2	A0A5S6PTQ4	A0A0H5S7S3	Uncharacterized protein.	BMA-FLN-2, isoform a; BMA-FLN-2, isoform c.	0.900
Bm1_11350	Bm1_25835	A0A0H5S590	A0A0K0J3W9	Bm5676.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.656
Bm1_11350	Bm1_26085	A0A0H5S590	A0A0H5SPB0	Bm5676.	Bm10748; Belongs to the protein kinase superfamily.	0.418
Bm1_11350	Bm1_31785	A0A0H5S590	A0A0K0J2R4	Bm5676.	Mitogen-activated protein kinase.	0.641
Bm1_11350	Bm1_39445	A0A0H5S590	A0A0K0J5Y2	Bm5676.	BMA-RAP-1.	0.506
Bm1_11350	Bm1_48560	A0A0H5S590	A0A0K0JPN5	Bm5676.	BMA-MEK-2; Belongs to the protein kinase superfamily.	0.983
Bm1_11350	Bm1_54585	A0A0H5S590	A0A0K0JYZ3	Bm5676.	BMA-SEK-3; Belongs to the protein kinase superfamily.	0.880
Bm1_11350	Bm2115	A0A0H5S590	A0A0K0J4I3	Bm5676.	Bm2115.	0.432
Bm1_11350	Bma-gpa-12	A0A0H5S590	A0A0H5SBA3	Bm5676.	BMA-GPA-12.	0.420
Bm1_11350	bma-cdc-42	A0A0H5S590	A0A1P6C408	Bm5676.	Bm5286, isoform a; Bm5286, isoform a; Bm5287, isoform a; Bm5287, isoform a.	0.432
Bm1_11350	bma-let-60	A0A0H5S590	A0A0K0J2J0	Bm5676.	BMA-LET-60.	0.506