STRINGSTRING
azo1520 azo1520 azo3585 azo3585 azo3589 azo3589 azo3594 azo3594 azo3917 azo3917 azo3193 azo3193 azo3206 azo3206 azo3255 azo3255 azo3256 azo3256 azo3257 azo3257 azo3258 azo3258 azo3259 azo3259 azo3262 azo3262 azo3268 azo3268 algD algD azo3270 azo3270 azo3272 azo3272 azo3274 azo3274 wzc2 wzc2 azo3282 azo3282 azo3510 azo3510 waaF2 waaF2 waaC2 waaC2 azo3567 azo3567 waaP1 waaP1 waaP2 waaP2 azo3571 azo3571 azo3576 azo3576 azo3578 azo3578 azo3580 azo3580 capD capD azo3584 azo3584 azo3189 azo3189 nosD nosD azo2694 azo2694 azo2680 azo2680 azo2675 azo2675 azo2381 azo2381 azo2380 azo2380 azo2323 azo2323 azo2322 azo2322 waaC1 waaC1 azo2318 azo2318 azo2314 azo2314 gumD gumD gumC gumC gumF gumF gumH gumH gumJ gumJ gumM gumM udgH udgH azo2162 azo2162 azo2161 azo2161 kdsA kdsA xanB xanB rmlA rmlA azo1809 azo1809 waaF1 waaF1 glgA glgA glgC glgC glgB2 glgB2 azo1788 azo1788 azo1785 azo1785 pep1 pep1 glgB1 glgB1 azo1721 azo1721 azo1720 azo1720 kdsB kdsB ndvC ndvC ndvB ndvB ugd ugd azo0965 azo0965 azo0856 azo0856 waaA waaA azo0793 azo0793 azo0751 azo0751 azo0750 azo0750 azo0749 azo0749 azo0746 azo0746 azo0650 azo0650 azo0386 azo0386 azo0349 azo0349
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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azo1520Conserved hypothetical membrane protein. Homology to CV1748 of C. violaceum of 32% (trembl|Q7NX80(SRS)). No domains predicted. No signal peptide 11 TMHs; Conserved hypothetical protein. (544 aa)
azo3585Glycosyltransferase; Putative glycosyl transferase MJ1057 (EC 2.-.-.-). InterPro: Glycosyl transferase family 2; Family membership. (247 aa)
azo3589Glycosyltransferase; InterPro: Glycosyl transferase family 2. Slight similarity to dolicholphosphate mannosyltransferases,might therefore transfer a sugar moiety directly to a lipid carrier; Specificity unclear. (277 aa)
azo3594Glycosyltransferase; Putative glycosyl transferase sll0501 (EC 2.-.-.-); Specificity unclear. (341 aa)
azo3917Glycosyltransferase; Specificity unclear. (255 aa)
azo3193Glycosyltransferase; Might transfer a sugar moiety directly to a lipd acceptor. Putative colanic biosynthesis UDP-glucose lipid carrier transferase. InterPro: Bacterial sugar transferase; Family membership. (460 aa)
azo3206Membrane protein, alkaline phosphatase superfamily. (685 aa)
azo3255Acyltransferase; Specificity unclear. (673 aa)
azo3256Conserved hypothetical polysaccharide biosynthesis protein, related to GumJ. Homology to ebA4295 of Azoarcus sp. EbN1 of 42%. Pfam: Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis SP5B_BACSU, which is involved in spore cortex biosynthesis. No signal peptide. 10 TMHs; Family membership. (458 aa)
azo3257Similar to putative exopolysaccharide polymerization protein PssK; Family membership. (347 aa)
azo3258Glycosyltransferase; InterPro: Glycosyl transferase family 2; Function unclear. (297 aa)
azo3259Glycosyltransferase; InterPro: Glycosyl transferase family 2; Specificity unclear. (308 aa)
azo3262Glycosyltransferase; Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-). InterPro: Glycosyl transferases group 1; Specificity unclear. (344 aa)
azo3268Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear. (408 aa)
algD[EC:1.1.1.132], UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH).,UDP-glucose/GDP-mannose dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; High confidence in function and specificity. (438 aa)
azo3270Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear. (403 aa)
azo3272Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear. (419 aa)
azo3274Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear. (391 aa)
wzc2Putative tyrosine-protein kinase (EC 2.7.10.1); High confidence in function and specificity. (313 aa)
azo3282Conserved hypothetical polysaccharide chain length determinant protein. Homology to ebA4249 of Azoarcus sp. EbN1 of 66%. No signal peptide. 3 TMHS. Pfam: Wzz = Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases such as ETK_ECOLI; Family membership. (514 aa)
azo3510InterPro: Sulfatase Membrane protein; Specificity unclear. (682 aa)
waaF2ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-); High confidence in function and specificity. (351 aa)
waaC2Lipopolysaccharide heptosyltransferase-1 (EC 2.-.-.-). HEPTOSE TRANSFER TO THE LIPOPOLYSACCHARIDE CORE. IT TRANSFERS THE INNNERMOST HEPTOSE TO [4-P](3-DEOXY-D-MANNO-OCTULOSONIC ACID)2-IVA. S18: ribosomal protein S18; High confidence in function and specificity. (363 aa)
azo3567Region start changed from 3913496 to 3913541 (-45 bases). (377 aa)
waaP1Lipopolysaccharide core biosynthesis protein; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family. (278 aa)
waaP2Lipopolysaccharide core biosynthesis protein rfaP. INVOLVED IN ATTACHMENT OF PHOSPHATE-CONTAINING SUBSTITUENTS TO THE INNER CORE. Specific function unclear. (249 aa)
azo3571Conserved hypothetical protein; InterPro: Eukaryotic protein kinase. Might be related to lipopolysaccharide biosynthesis, due to the presence of the gene in a lipopolysaccharide gene cluster. (485 aa)
azo3576Conserved hypothetical protein. (318 aa)
azo3578Glycosyltransferase; Specificity unclear. (376 aa)
azo3580Putative acyltransferase family protein; Catalysis of the reactions of the type: acyl-carrier + reactant = acyl-reactant + carrier. Entry name : Q888M0 InterPro : IPR002656; Acyl_transf_3. Identity: 227/677 (33%) Pfam PF01757; Acyl_transf_3; 1. Prediction: Non-secretory protein Signal peptide probability: 0.005(almost Yes) Number of predicted TMHs: 10; Family membership. (687 aa)
capDPutative capsular polysaccharide biosynthesis protein; 48% Polysac_CapD. Pfam:PF02719; Polysacc_synt_2; 1; High confidence in function and specificity. (621 aa)
azo3584Glycosyltransferase; InterPro: Glycosyl transferases group 1; Specificity unclear. (393 aa)
azo3189NDPsugar dehydrogenase; CapL protein. Required for the biosynthesis of type 1 capsular polysaccharide. InterPro: UDP-glucose/GDP-mannose dehydrogenase family gutA: pts system glucitol/sorbitol-s; Specificity unclear. (426 aa)
nosDCopper-binding periplasmic protein precursor. INVOLVED IN COPPER PROCESSING AND TRANSPORT; IN THE ASSEMBLY OF THE COPPER CHROMOPHORES OF NITROUS OXIDE REDUCTASE.Part of the ABC transporter complex nosDFY involved in copper import. Similar to the putative periplasmic-binding protein nosD precursor from: P.fluorescens (36%)TREMBL:Q9F0W3 InterPro:IPR006633; CASH. IPR007742; NosD.IPR006626; PbH1. Pfam:PF05048; NosD; 1. Signal peptide: present; High confidence in function and specificity. (425 aa)
azo2694Nucleotide sugar aminotransferase; InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
azo2680Glycosyltransferase; Bactoprenol glucosyl transferase (EC 2.4.1.-). Involved in O antigen modification. Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (By similarity); Specificity unclear. (313 aa)
azo2675Aminotransferase; Lipopolysaccharide biosynthesis protein rffA. InterPro: DegT/DnrJ/EryC1/StrS family; Specificity unclear; Belongs to the DegT/DnrJ/EryC1 family. (380 aa)
azo2381Dolichyl-phosphate-mannose-protein mannosyltransferase; Conserved hypothetical protein. Extremely weak homology with hits in the Database spanning the entire length of protein. Has PF02366, Dolichyl-phosphate-mannose-protein mannosyltransferase; IPR003342,Glyco_trans_39:This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins. These proteins are responsible for O-linked glycosylation of proteins, they catalyse the reaction:-Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Q94891 Drosophila rotated ab [...] (515 aa)
azo2380Glycosyltransferase; Specificity unclear. (368 aa)
azo2323Glycosyltransferase; Lipopolysaccharide core biosynthesis glycosyl transferase lpsE (EC 2.-.-.-); Specificity unclear. (356 aa)
azo2322Glycosyltransferase; Hypothetical glycosyl transferase MJ1607 (EC 2.-.-.-). InterPro: Glycosyl transferases group 1; Specificity unclear. (371 aa)
waaC1Lipopolysaccharide heptosyltransferase I; High confidence in function and specificity. (358 aa)
azo2318Hypothetical membrane protein. homology to rsc2204 of R.solanacearum of 28% (trembl|Q8XXB2(SRS)). no domains predicted. no signal peptide. 10 TMHs. (428 aa)
azo2314Glycosyltransferase; Family membership. (500 aa)
gumDPutative glycosyltransferase; 43% Bact_transf. Pfam:PF02397; Bac_transf; 1. TMhelix:5; Specificity unclear. (463 aa)
gumCPutative exopolysaccharide biosynthesis protein; 21% LPS_Wzz_MPA. Pfam:PF02706; Wzz; 1. TMhelix:1. Signal peptide:present; High confidence in function and specificity. (469 aa)
gumFPutative acetyltransferase; 44% Acyl_transf_3. Pfam:PF01757; Acyl_transf_3; 1. TMhelix:9. Non-secretory protein; High confidence in function and specificity. (362 aa)
gumHPutative glycosyltransferase; 60% Glyco_trans_1. Pfam:PF00534; Glycos_transf_1; 1; Specificity unclear. (371 aa)
gumJPutative polysaccharide translocase; 25% Polysacc_synt. Pfam:PF01943; Polysacc_synt; 1. TMhelix:14. Non-secretory protein; Family membership. (490 aa)
gumMPutative glycosyltransferase; 60% WecB_TagA_CpsF. Pfam:PF03808; Glyco_tran_WecB; 1. TIGRFAMs:TIGR00696; wecB_tagA_cpsF; 1. Non-secretory protein; High confidence in function and specificity; Belongs to the glycosyltransferase 26 family. (252 aa)
udgHPutative UDP-glucose 6-dehydrogenase; 61% UDPG_MGDP_dh. Pfam:PF00984; UDPG_MGDP_dh; 1.PF03720; UDPG_MGDP_dh_C; 1.PF03721; UDPG_MGDP_dh_N; 1. Signal peptide: present; High confidence in function and specificity. (440 aa)
azo2162Conserved hypothetical protein, similar to glycosyltransferases; Hypothetical protein AQ_1704; Family membership. (542 aa)
azo2161Glycosyltransferase,; Specificity unclear. (348 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55) (Phospho-2- dehydro-3-deoxyoctonate aldolase) (3-deoxy-D-manno-octulosonic acid 8- phosphate synthetase) (KDO-8-phosphate synthetase) (KDO 8-P synthase) (KDOPS). Homology to kdsA of Pseudomonas aeruginosa of 45% (gi|6647573|sp|Q9ZFK4|KDSA_PSEAE(SwissProt (ExPASy))). Tigrfam: 3-deoxy-8-phosphooctulonate synthase. This HMM describes 3-deoxy-8-phosphooctulonate synthase. Alternate names include 2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-d-manno-octulosonic acid 8-phosphate and KDO-8 phosphate synthetase. It catalyzes the aldo [...] (279 aa)
xanBProbable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership. (482 aa)
rmlAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa)
azo1809Glycosyltransferase; Hypothetical protein Rv0486/MT0504/Mb0496. InterPro: Glycosyl transferases group 1; Specificity unclear. (419 aa)
waaF1ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-). pdxJ: pyridoxal phosphate biosynthetic; High confidence in function and specificity. (404 aa)
glgAPutative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (558 aa)
glgCPutative glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (404 aa)
glgB214-alpha-glucan branching enzyme (Glycogen branching enzyme)(BE) (14-alpha-D-glucan:14-alpha-D-glucan 6-glucosyl- transferase). Catalyzes the formation of the alpha-16-glucosidic linkages in glycogen by scission of a 14-alpha-linked oligosaccharide from growing alpha-14-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-16 position. 36% Alpha_amyl_cat.IPR006407;GlgB.IPR004193;Glyco_hydro_13N. Pfam:PF00128; Alpha-amylase; 1.PF02922; Isoamylase_N; 1. TIGRFAMs:TIGR01515; branching_enzym; 1; High confidence in function and specificity. (605 aa)
azo1788Glycosyltransferase; InterPro: Glycosyl transferases group 1; Family membership. (377 aa)
azo1785Glycosyltransferase; InterPro: Glycosyl transferases group 1; Family membership. (390 aa)
pep1Putative glucanohydrolase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (682 aa)
glgB1Putative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (637 aa)
azo1721Heptosyltransferase; Similar to waaQ; Family membership. (352 aa)
azo1720Glycosyltransferase; Family membership. (377 aa)
kdsBProbable 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (257 aa)
ndvCPutative glucan 1,3-beta-glucosidase; Glucan 1-3-beta-glucosidase precursor.(Exo-13-beta-glucanase).Glucanases possibly play a role in cell expansion during growth in cell-cell fusion during mating and in spore release during sporulation. This enzyme may be involved in beta- glucan degradation and also function biosynthetically as a transglycosylase. 47%; Function unclear. (531 aa)
ndvBBeta-(1-3)-glucosyl transferase, involved in the synthesis of the cyclic beta-(1,3),(1,6)-D-glucan. 36% Glyco_trans_2. Pfam:PF00535; Glycos_transf_2. Signal peptide: present. TMhelix:9; Function unclear. (872 aa)
ugdUDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH); High confidence in function and specificity. (440 aa)
azo0965Glycosyltransferase; InterPro: Glycosyl transferases group 1; Family membership. (407 aa)
azo0856Glycosyltransferase; Similar to amylovoran biosynthesis glycosyl transferase amsK (EC 2.-.-.-). INVOLVED IN THE BIOSYNTHESIS OF AMYLOVORAN WHICH FUNCTIONS AS A VIRULENCE FACTOR. Similar to protein annotated as sulfolipid sulfoquinovosyldiacylglycerol biosynthesis proteins; Family membership. (423 aa)
waaA3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (414 aa)
azo0793Probable phosphatase (HAD superfamily); Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate TREMBL:Q9JSU3: 43% identity, 59% similarity InterPro: IPR006549; HAD-SF-IIIA. IPR005834; Hydrolase. IPR008230; Sugar_Ptase. IPR010023; YrbI_phosphatas. Pfam: PF00702; Hydrolase TIGR00099: conserved hypothetical prote Absence of transmembrane helices; Specificity unclear. (173 aa)
azo0751Conserved hypothetical membrane protein. Homology to PA4820 of P. aeruginosa of 38% (trembl|Q9HUZ0(SRS)) Has PF04138, GtrA-like protein;IPR007267;Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylatio [...] (133 aa)
azo0750Conserved hypothetical membrane protein. TREMBL:Q89QQ8: 34% identity This is a subfamily of bacterial binding-protein-dependent transport systems family, and includes transport system permease proteins involved in the transport across the membrane of several compounds. This entry contains the inner components of this multicomponent transport system InterPro: IPR000522; FecD. Pfam: PF01032; FecCD ncs1: NCS1 nucleoside transporter fam Nonsecretory protein with signal peptide probability 0.203 (Signal P predicted). TMHMM predicted 9 transmembrane helices; Function unclear. (532 aa)
azo0749Conserved hypothetical glycosyl transferase. Homology to cc2889 of. C. crescentus (trembl|Q9A4E5). Pfam: Glycosyl transferase family 2(PF00535). Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. Interpro: Glycosyl transferase family 2 (IPR001173). no signal peptide. 2 TMHs; Conserved hypothetical protein. (342 aa)
azo0746Hypothetical membrane protein. Homology to la0834 of L. interrogans of 25% (trembl|Q8F7U9). InterPro: Dolichyl-phosphate-mannose-protein mannosyltransferase (IPR003342). Dolichyl-phosphate-mannose-protein mannosyltransferase proteins belong to the glycosyltransferase family 39 and are responsible for O-linked glycosylation of proteins. They catalyse the reaction: Dolichyl phosphate D-mannose + protein -> dolichyl phosphate + O-D-mannosyl-protein. Pfam: Dolichyl-phosphate-mannose-protein mannosyltransferase. signal peptide. 10 TMHs. (541 aa)
azo0650Conserved hypothetical glycosyltransferase. Homology to gsu0991 of G. sulfurreducens of 30% (tremblnew|AAR34318) Pfam: Glycosyl transferase group 1 no signal peptide no TMHs; Conserved hypothetical protein. (408 aa)
azo0386Hypothetical membrane protein. No good homology to a protein of similar length in the data bank. no domains predicted no singal peptide 9 TMHs. (418 aa)
azo0349Putative Small Multi-Drug resistant(SMR)family protein, 30% identical to TrEMBL;Q8XZS2. Has PF00893,Small Multidrug Resistance protein;IPR000390, Smr:This family is the Small Multidrug Resistance (SMR) family. Several members have been shown to export a range of toxins, including ethidium bromide and quaternary ammonium compounds, through coupling with proton influx. (121 aa)
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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