(8 nodes) Riboflavin metabolism network (Kingella oralis)

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	ribA	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (235 aa)
	RibF	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953. (122 aa)
	ribE	KEGG: nma:NMA1416 6.3e-75 ribC; putative riboflavin synthase alpha subunit K00793. (205 aa)
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (152 aa)
	frp	KEGG: vpa:VPA1601 4.0e-57 NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family. (245 aa)
	ribB	3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (389 aa)
	aphA	HAD phosphatase, family IIIB; KEGG: sag:SAG0635 2.1e-60 acid phosphatase, class B K03788. (242 aa)
	ribD	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (359 aa)

Your Current Organism:

Kingella oralis

NCBI taxonomy Id: 629741
Other names: K. oralis ATCC 51147, Kingella oralis ATCC 51147, Kingella oralis str. ATCC 51147, Kingella oralis strain ATCC 51147

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RibF	aphA	GCWU000324_00387	GCWU000324_02964	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	HAD phosphatase, family IIIB; KEGG: sag:SAG0635 2.1e-60 acid phosphatase, class B K03788.	0.900
RibF	frp	GCWU000324_00387	GCWU000324_01757	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	KEGG: vpa:VPA1601 4.0e-57 NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family.	0.900
RibF	ribA	GCWU000324_00387	GCWU000324_00223	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.463
RibF	ribB	GCWU000324_00387	GCWU000324_02563	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.664
RibF	ribD	GCWU000324_00387	GCWU000324_03130	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.771
RibF	ribE	GCWU000324_00387	GCWU000324_00841	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	KEGG: nma:NMA1416 6.3e-75 ribC; putative riboflavin synthase alpha subunit K00793.	0.939
RibF	ribH	GCWU000324_00387	GCWU000324_01596	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.873
aphA	RibF	GCWU000324_02964	GCWU000324_00387	HAD phosphatase, family IIIB; KEGG: sag:SAG0635 2.1e-60 acid phosphatase, class B K03788.	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	0.900
aphA	frp	GCWU000324_02964	GCWU000324_01757	HAD phosphatase, family IIIB; KEGG: sag:SAG0635 2.1e-60 acid phosphatase, class B K03788.	KEGG: vpa:VPA1601 4.0e-57 NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family.	0.911
aphA	ribE	GCWU000324_02964	GCWU000324_00841	HAD phosphatase, family IIIB; KEGG: sag:SAG0635 2.1e-60 acid phosphatase, class B K03788.	KEGG: nma:NMA1416 6.3e-75 ribC; putative riboflavin synthase alpha subunit K00793.	0.900
frp	RibF	GCWU000324_01757	GCWU000324_00387	KEGG: vpa:VPA1601 4.0e-57 NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family.	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	0.900
frp	aphA	GCWU000324_01757	GCWU000324_02964	KEGG: vpa:VPA1601 4.0e-57 NADPH-flavin oxidoreductase; Belongs to the flavin oxidoreductase frp family.	HAD phosphatase, family IIIB; KEGG: sag:SAG0635 2.1e-60 acid phosphatase, class B K03788.	0.911
ribA	RibF	GCWU000324_00223	GCWU000324_00387	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	0.463
ribA	ribB	GCWU000324_00223	GCWU000324_02563	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.995
ribA	ribD	GCWU000324_00223	GCWU000324_03130	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.998
ribA	ribE	GCWU000324_00223	GCWU000324_00841	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	KEGG: nma:NMA1416 6.3e-75 ribC; putative riboflavin synthase alpha subunit K00793.	0.986
ribA	ribH	GCWU000324_00223	GCWU000324_01596	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.961
ribB	RibF	GCWU000324_02563	GCWU000324_00387	3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	KEGG: nma:NMA0621 3.1e-34 ribF; putative riboflavin kinase/FMN adenylyltransferase K00861:K00953.	0.664
ribB	ribA	GCWU000324_02563	GCWU000324_00223	3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.995
ribB	ribD	GCWU000324_02563	GCWU000324_03130	3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.999