STRINGSTRING
rraB rraB zapC zapC nlpI nlpI slyX slyX yihI yihI metJ metJ fabR fabR yijD yijD yifE yifE mutH mutH yejK yejK yejL yejL yejM yejM syd syd CH53_3106 CH53_3106 seqA seqA tolA tolA dsbB dsbB fadR fadR yfbV yfbV dedD dedD prc prc proQ proQ CH53_430 CH53_430 CH53_436 CH53_436
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rraBRegulator of ribonuclease activity B; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. (143 aa)
zapCHypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (183 aa)
nlpILipoprotein nlpI; May be involved in cell division. (294 aa)
slyXslyX family protein; Belongs to the SlyX family. (72 aa)
yihIDer GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. (188 aa)
metJMet Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. (105 aa)
fabRHTH-type transcriptional repressor fabR; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (210 aa)
yijDInner membrane protein yijD. (131 aa)
yifEHypothetical protein. (112 aa)
mutHDNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (228 aa)
yejK37-kD nucleoid-associated bacterial family protein. (334 aa)
yejLHypothetical protein; Belongs to the UPF0352 family. (75 aa)
yejMType I phosphodiesterase / nucleotide pyrophosphatase family protein. (597 aa)
sydProtein syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. (183 aa)
CH53_3106Ribbon-helix-helix, copG family protein. (95 aa)
seqAProtein seqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. (175 aa)
tolAtolA_full: protein TolA. (389 aa)
dsbBDisulfide bond formation DsbB family protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa)
fadRFatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism. (239 aa)
yfbVHypothetical protein. (151 aa)
dedDSporulation related domain protein; Non-essential cell division protein that could be required for efficient cell constriction. (243 aa)
prcTail-specific protease; Belongs to the peptidase S41A family. (686 aa)
proQproP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. (237 aa)
CH53_430yfcL family protein. (91 aa)
CH53_436Smr domain protein; Belongs to the UPF0115 family. (176 aa)
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.