STRINGSTRING
arcA_1 arcA_1 yfiN yfiN hmsT_1 hmsT_1 limB limB basR_1 basR_1 basS basS ycgG_2 ycgG_2 trg_2 trg_2 epaO epaO CH53_1416 CH53_1416 rcsC_1 rcsC_1 nreC nreC envZ_1 envZ_1 ompR ompR yhjH_1 yhjH_1 yhjK yhjK uhpC_2 uhpC_2 nreB_2 nreB_2 uhpA uhpA cheM cheM tar_1 tar_1 ssuE ssuE fixL fixL fixJ_1 fixJ_1 CH53_1745 CH53_1745 ntrC ntrC glnL glnL zraR_3 zraR_3 echA8 echA8 gmr_3 gmr_3 cpxA cpxA cpxR cpxR cpxP cpxP csrD csrD rpoN rpoN arcB arcB trg_3 trg_3 flhA_2 flhA_2 motB_2 motB_2 gmr_2 gmr_2 pleD_2 pleD_2 gmr_4 gmr_4 evgA evgA evgS evgS ycgG_1 ycgG_1 ygfY ygfY CH53_2629 CH53_2629 blrA blrA creC creC creD creD ydaM_1 ydaM_1 cheD_2 cheD_2 glnD glnD cutF cutF phoB phoB phoR phoR glnK glnK amt amt cheD2 cheD2 adrA_3 adrA_3 tar_2 tar_2 bvgS_2 bvgS_2 bvgA_2 bvgA_2 hyfR_1 hyfR_1 ybjJ_3 ybjJ_3 rcsD rcsD rcsB rcsB rcsC_3 rcsC_3 cheV cheV bvgS_1 bvgS_1 bvgA bvgA uhpC_1 uhpC_1 nreB_1 nreB_1 uhpA_1 uhpA_1 zraR zraR zraS zraS trg_1 trg_1 motA motA motB motB cheA cheA cheW cheW cheD_1 cheD_1 tap tap cheR cheR cheB cheB cheY cheY cheZ cheZ flhB flhB flhA flhA flgN flgN flgM flgM flgA flgA flgB flgB flgC flgC flgD flgD flgE flgE flgF flgF flgG flgG flgH flgH flgI flgI flgJ flgJ flgK flgK flgL flgL fliR fliR fliQ fliQ fliP fliP fliO fliO fliN fliN fliM fliM fliL fliL fliK fliK fliJ fliJ fliI fliI fliH fliH fliG fliG fliF fliF fliE fliE fliT fliT fliS fliS fliD fliD fliC fliC fliA fliA fliZ fliZ adrA_1 adrA_1 tap_1 tap_1 uvrY uvrY narP narP narX narX dosC dosC dosP dosP rssA rssA hnr hnr cdgR cdgR CH53_3973 CH53_3973 CH53_4029 CH53_4029 rstA rstA rstB rstB ypwA ypwA asr asr tyrR tyrR pspF pspF pleD_1 pleD_1 cph2_1 cph2_1 CH53_4305 CH53_4305 adrA_2 adrA_2 cph2_2 cph2_2 aer aer phoP phoP phoQ phoQ cpxA_1 cpxA_1 ompR_1 ompR_1 narL narL glnB glnB qseF qseF qseG qseG glrK glrK hmsT_2 hmsT_2 barA_2 barA_2 barA_1 barA_1 yjcC yjcC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arcA_1Hypothetical protein; Transcriptional regulatory, C terminal family protein. (238 aa)
yfiNGGDEF: diguanylate cyclase domain protein. (432 aa)
hmsT_1GGDEF: diguanylate cyclase domain protein. (360 aa)
limBOxido_grp_1: luciferase oxidoreductase, group 1 family protein. (340 aa)
basR_1Hypothetical protein; Transcriptional regulatory, C terminal family protein. (220 aa)
basSHAMP domain protein. (360 aa)
ycgG_2EAL domain protein. (509 aa)
trg_2Hypothetical protein. (551 aa)
epaOspaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family. (318 aa)
CH53_1416hrpE_YscL_not: type III secretion apparatus protein, HrpE/YscL family. (207 aa)
rcsC_1HAMP domain protein. (940 aa)
nreCBacterial regulatory s, luxR family protein. (210 aa)
envZ_1HAMP domain protein. (450 aa)
ompRTranscriptional regulatory protein ompR. (239 aa)
yhjH_1EAL domain protein. (263 aa)
yhjKGGDEF: diguanylate cyclase domain protein. (667 aa)
uhpC_22A0104: phosphoglycerate transporter family protein. (443 aa)
nreB_2Histidine kinase family protein. (510 aa)
uhpATranscriptional regulatory protein uhpA. (196 aa)
cheMMethyl-accepting chemotaxis (MCP) signaling domain protein. (653 aa)
tar_1Methyl-accepting chemotaxis (MCP) signaling domain protein. (634 aa)
ssuENADPH-dependent FMN reductase family protein. (190 aa)
fixLHis Kinase A domain protein. (449 aa)
fixJ_1Bacterial regulatory s, luxR family protein. (205 aa)
CH53_1745Hypothetical protein. (164 aa)
ntrCNitrogen regulation protein NR; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (470 aa)
glnLNitrogen regulation protein NR. (349 aa)
zraR_3AAA domain family protein. (752 aa)
echA8enoyl-CoA hydratase/isomerase family protein. (288 aa)
gmr_3GGDEF: diguanylate cyclase domain protein. (664 aa)
cpxASensor protein CpxA. (458 aa)
cpxRTranscriptional regulatory protein CpxR. (232 aa)
cpxPPeriplasmic protein CpxP. (165 aa)
csrDRNase E specificity factor CsrD. (639 aa)
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)
arcBSensory box protein. (778 aa)
trg_3Hypothetical protein. (526 aa)
flhA_2FHIPEP family protein. (564 aa)
motB_2ompA family protein. (241 aa)
gmr_2GGDEF: diguanylate cyclase domain protein. (855 aa)
pleD_2GGDEF: diguanylate cyclase domain protein. (350 aa)
gmr_4GGDEF: diguanylate cyclase domain protein. (625 aa)
evgAPositive transcription regulator evgA. (204 aa)
evgSSensor protein evgS. (1204 aa)
ycgG_1EAL domain protein. (533 aa)
ygfYFlavinator of succinate dehydrogenase family protein. (88 aa)
CH53_2629Hypothetical protein. (142 aa)
blrAResponse regulator. (231 aa)
creCHAMP domain protein. (475 aa)
creDInner membrane CreD family protein. (468 aa)
ydaM_1Putative diguanylate cyclase YdaM. (414 aa)
cheD_2Hypothetical protein. (557 aa)
glnDprotein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (892 aa)
cutFnlpE N-terminal domain protein. (233 aa)
phoBphoB: phosphate regulon transcriptional regulatory protein PhoB. (229 aa)
phoRphoR_proteo: phosphate regulon sensor kinase PhoR. (438 aa)
glnKNitrogen regulatory protein P-II 2; Belongs to the P(II) protein family. (112 aa)
amtAmt: ammonium transporter family protein. (429 aa)
cheD2Methyl-accepting chemotaxis (MCP) signaling domain protein. (595 aa)
adrA_3Putative diguanylate cyclase AdrA. (366 aa)
tar_2Hypothetical protein. (553 aa)
bvgS_2His Kinase A domain protein. (1064 aa)
bvgA_2Bacterial regulatory s, luxR family protein. (202 aa)
hyfR_1AAA domain family protein. (719 aa)
ybjJ_3Major Facilitator Superfamily protein. (384 aa)
rcsDHpt domain protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (897 aa)
rcsBrcsB protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. (217 aa)
rcsC_3rcsC Alpha-Beta-Loop family protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (932 aa)
cheVResponse regulator. (325 aa)
bvgS_1Hpt domain protein. (1288 aa)
bvgAVirulence factors putative positive transcription regulator BvgA. (210 aa)
uhpC_1Major Facilitator Superfamily protein. (441 aa)
nreB_1Histidine kinase family protein. (525 aa)
uhpA_1Bacterial regulatory s, luxR family protein. (209 aa)
zraRTranscriptional regulatory protein zraR. (449 aa)
zraSHis Kinase A domain protein. (479 aa)
trg_1Hypothetical protein. (579 aa)
motAmotA1: flagellar motor stator protein MotA. (295 aa)
motBMotility protein B. (397 aa)
cheAChemotaxis protein CheA. (688 aa)
cheWcheW-like domain protein. (165 aa)
cheD_1Hypothetical protein. (557 aa)
tapMethyl-accepting chemotaxis protein IV. (545 aa)
cheRChemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (287 aa)
cheBcheB methylesterase family protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa)
cheYChemotaxis protein CheY. (129 aa)
cheZProtein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (214 aa)
flhBFlagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (382 aa)
flhAFlagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (692 aa)
flgNflgN family protein. (146 aa)
flgMflgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM. (99 aa)
flgAFlagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (226 aa)
flgBFlagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (137 aa)
flgCflgC: flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family. (134 aa)
flgDHypothetical protein; Required for flagellar hook formation. May act as a scaffolding protein. (230 aa)
flgEflgEFG_subfam: flagellar hook-basal body family protein. (428 aa)
flgFFlagellar basal-body rod protein flgF. (251 aa)
flgGflgG_G_neg: flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family. (260 aa)
flgHFlagellar L-ring family protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (219 aa)
flgIFlagellar P-ring family protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (373 aa)
flgJflagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ. (313 aa)
flgKflgK_ends: flagellar hook-associated protein FlgK. (555 aa)
flgLflagell_flgL: flagellar hook-associated protein 3. (326 aa)
fliRFlagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (260 aa)
fliQFlagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (279 aa)
fliOfliO_TIGR: flagellar biosynthetic protein FliO. (124 aa)
fliNFlagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. (138 aa)
fliMFlagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (334 aa)
fliLFlagellar basal body-associated FliL family protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (156 aa)
fliKFlagellar hook-length control FliK family protein. (452 aa)
fliJFlagellar export protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (148 aa)
fliIfliI_clade1: flagellar protein export ATPase FliI. (454 aa)
fliHFlagellar assembly FliH family protein. (242 aa)
fliGFlagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (330 aa)
fliFFlagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (572 aa)
fliEfliE: flagellar hook-basal body complex protein FliE. (103 aa)
fliTFlagellar protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (120 aa)
fliSfliS: flagellar protein FliS. (132 aa)
fliDFlagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (468 aa)
fliCHypothetical protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (497 aa)
fliARNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (240 aa)
fliZfliZ: flagellar regulatory protein FliZ. (169 aa)
adrA_1GGDEF: diguanylate cyclase domain protein. (328 aa)
tap_1Methyl-accepting chemotaxis (MCP) signaling domain protein. (523 aa)
uvrYResponse regulator. (218 aa)
narPBacterial regulatory s, luxR family protein. (216 aa)
narXNitrate/nitrite sensor protein narX. (593 aa)
dosCGGDEF: diguanylate cyclase domain protein. (372 aa)
dosPGGDEF: diguanylate cyclase domain protein. (865 aa)
rssAPatatin-like phospholipase family protein. (299 aa)
hnrResponse regulator; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. (338 aa)
cdgREAL domain protein. (233 aa)
CH53_3973Bacterial regulatory s, luxR family protein. (238 aa)
CH53_4029Hypothetical protein. (138 aa)
rstAResponse regulator. (242 aa)
rstBHAMP domain protein. (434 aa)
ypwACarboxypeptidase Taq (M32) metallopeptidase family protein; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. (493 aa)
asrHypothetical protein. (93 aa)
tyrRTranscriptional regulatory protein tyrR. (525 aa)
pspFphageshock_pspF: psp operon transcriptional activator. (341 aa)
pleD_1GGDEF: diguanylate cyclase domain protein. (335 aa)
cph2_1GGDEF: diguanylate cyclase domain protein. (569 aa)
CH53_4305EAL domain protein. (519 aa)
adrA_2GGDEF: diguanylate cyclase domain protein. (693 aa)
cph2_2GGDEF: diguanylate cyclase domain protein. (467 aa)
aerSensory box protein. (519 aa)
phoPTranscriptional regulatory protein phoP. (223 aa)
phoQVirulence sensor histidine kinase phoQ. (468 aa)
cpxA_1HAMP domain protein. (455 aa)
ompR_1Response regulator. (227 aa)
narLBacterial regulatory s, luxR family protein. (209 aa)
glnBNitrogen regulatory protein P-II; Belongs to the P(II) protein family. (112 aa)
qseFAAA domain family protein. (445 aa)
qseGyfhG lipofamily protein. (394 aa)
glrKHAMP domain protein. (478 aa)
hmsT_2GGDEF: diguanylate cyclase domain protein. (319 aa)
barA_2Sensory box protein. (1521 aa)
barA_1HAMP domain protein. (920 aa)
yjcCEAL domain protein. (512 aa)
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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