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gdhA gdhA pgiA pgiA pykA pykA talA1 talA1 pgkA pgkA fbpA fbpA enoA enoA pfp pfp tpiA tpiA pfkA pfkA gapA gapA fbaB fbaB pfkB pfkB gpmA gpmA gapN gapN gapB gapB talA2 talA2 gapC gapC fbaA fbaA gapD gapD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
gene fusions
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gdhAGlucose dehydrogenase catalyses the oxidation of D-glucose without prior phosphorylation to D-beta-gluconolactone using NAD or NADP as a coenzyme; Belongs to the short-chain dehydrogenases/reductases family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity. (272 aa)
pgiAGlucose-6-phosphate isomerase is a dimeric enzyme that catalyses the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate in the second step of glycolysis (Embden-Meyerhof pathway) and in oxydative phase of pentose phosphate pathway. PgiA also is involved in the gluconeogenesis and in Pentose phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the GPI family. (545 aa)
pykAPyruvate kinase (PK) catalyzes the final step in glycolysis (Embden-Meyerhof pathway), the conversion of phosphoenolpyruvate to pyruvate with concomitant phosphorylation of ADP to ATP. PK forms a homotetramer and requires both magnesium and potassium ions for its activity. PK helps control the rate of glycolysis, along with phosphofructokinase and hexokinase. PK possesses allosteric sites for numerous effectors; Localized in the cytoplasm; High confidence in function and specificity. (476 aa)
talA1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
pgkAPhosphoglycerate kinase transfers a phosphate group from 1,3-biphosphoglycerate to ADP, forming ATP and 3-Phosphoglycerate in the seventh step of the glycolysis Embden-Meyerhof pathway). PgkA exists as a monomer containing two nearly equal-sized domains that correspond to the N- and C-termini of the protein. 3-phosphoglycerate binds to the N-terminal, while the nucleotide substrates, MgATP or MgADP, bind to the C-terminal domain of the enzyme; Localized in the cytoplasm; High confidence in function and specificity. (396 aa)
fbpAFructose-1,6-bisphosphatase is involved in glycolysis / gluconeogenesis and in mannose and fructose metabolism. It removes one phosphate group from D-fructose 1,6-bisphosphate to form D-fructose 6-phosphate. The catalytic mechanism of FbpA is dependent of Mg2+; Belongs to the inositol polyphosphate 1 phosphatase like superfamily; Localized in the cytoplasm; High confidence in function and specificity. (336 aa)
enoAEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
pfpDiphosphate-fructose-6-phosphate 1-phosphotransferase catalyzes the reversible phosphorylation of fructose-6-phosphate using pyrophoshate instead of ATP for phosphofructokinase (Pfk). Involved in glycolysis. It forms a homotetramer. Localized in the cytoplasm; High confidence in function and specificity. (408 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
pfkA6-Phosphofructokinase, isoenzyme 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity. (333 aa)
fbaBFructose-bisphosphate aldolase, class 1; Fructose-bisphosphate aldolase catalyzes the fourth step of the glycolysis (Embden-Meyerhof pathway). It cleaves the hexose D-fructose 1,6-bisphosphate into two trioses sugars: the dihydroxyacetone phosphate (ketone) and the D-glyceraldehyde 3-phosphate (aldehyde); Belongs to the DeoC/LacD aldolase family (Common phosphate binding- site TIM barrel superfamily); Localized in the cytoplasm; High confidence in function and specificity. (348 aa)
pfkB6-Phosphofructokinase, isozyme 2; 6-Phosphofructokinase catalyzes the thirth step of glycolysis (Embden-Meyerhof pathway). It phosphoryles the D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. It is an allosteric homodimer enzyme. Because the reaction catalyzed by Phosphofructokinase is energetically very favorable, it is essentially irreversible; Belongs to the carbohydrate kinase PfkB family; Localized in the cytoplasm; High confidence in function and specificity. (313 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa)
gapNThe NADP-dependent glyceraldehyde-3-phosphate dehydrogenase is important as a means of generating NADPH for biosynthetic reactions. It converts the D-glyceraldehyde 3-phosphate to 3-phospho-D-glycerate; Forms a homotetramer and binds a NADP+ per subunit as cofactors; Localized in the cytoplasm; High confidence in function and specificity. (526 aa)
gapBGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity. (329 aa)
talA2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
gapCGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis (Embden-Meyerhof pathway) and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3- phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity. (336 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (355 aa)
gapDGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity. (482 aa)
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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