STRINGSTRING
murA murA murB murB ddl ddl murA-2 murA-2 glmU glmU ADQ40281.1 ADQ40281.1 ADQ40378.1 ADQ40378.1 ADQ40745.1 ADQ40745.1 ADQ40771.1 ADQ40771.1 ADQ41082.1 ADQ41082.1 ADQ41083.1 ADQ41083.1 ADQ41084.1 ADQ41084.1 ADQ41270.1 ADQ41270.1 ftsZ ftsZ ADQ41409.1 ADQ41409.1 ADQ41410.1 ADQ41410.1 ADQ41411.1 ADQ41411.1 murA-3 murA-3 murG murG ADQ41414.1 ADQ41414.1 murD murD mraY mraY murF murF murE murE ADQ41419.1 ADQ41419.1 ADQ41420.1 ADQ41420.1 rsmH rsmH mraZ mraZ ADQ41423.1 ADQ41423.1 lgt lgt ADQ41425.1 ADQ41425.1 ADQ41426.1 ADQ41426.1 ADQ41427.1 ADQ41427.1 ADQ41428.1 ADQ41428.1 murC murC ADQ41950.1 ADQ41950.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (414 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (314 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (364 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (465 aa)
ADQ40281.1TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: ate:Athe_1946 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase. (385 aa)
ADQ40378.1TIGRFAM: nucleotide sugar dehydrogenase; KEGG: ate:Athe_1818 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (426 aa)
ADQ40745.1PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: ate:Athe_1255 serine-type D-Ala-D-Ala carboxypeptidase. (451 aa)
ADQ40771.1KEGG: ate:Athe_1280 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein. (387 aa)
ADQ41082.1KEGG: ate:Athe_1559 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein. (386 aa)
ADQ41083.1KEGG: ate:Athe_1560 spore cortex-lytic enzyme; TIGRFAM: spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein. (225 aa)
ADQ41084.1KEGG: ate:Athe_1561 hypothetical protein. (101 aa)
ADQ41270.1PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Mur ligase middle domain protein; KEGG: ate:Athe_0527 Mur ligase middle domain protein. (741 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (360 aa)
ADQ41409.1PFAM: protein of unknown function DUF1290; KEGG: ate:Athe_0782 hypothetical protein. (120 aa)
ADQ41410.1PFAM: protein of unknown function DUF881; KEGG: ate:Athe_0781 protein of unknown function DUF881. (247 aa)
ADQ41411.1Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. (244 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (442 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (369 aa)
ADQ41414.1KEGG: ate:Athe_0777 cell division protein FtsW; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; Belongs to the SEDS family. (361 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (458 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (320 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (448 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
ADQ41419.1SMART: PASTA domain containing protein; TIGRFAM: stage V sporulation protein D; KEGG: ate:Athe_0772 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein. (719 aa)
ADQ41420.1PFAM: Septum formation initiator; KEGG: ate:Athe_0771 septum formation initiator. (166 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (307 aa)
mraZMraZ protein; KEGG: ate:Athe_0769 cell division protein MraZ; TIGRFAM: MraZ protein; PFAM: MraZ domain; Belongs to the MraZ family. (143 aa)
ADQ41423.1KEGG: ate:Athe_0768 hypothetical protein. (59 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (267 aa)
ADQ41425.1PFAM: peptidase M16 domain protein; KEGG: ate:Athe_0766 peptidase M16 domain protein. (433 aa)
ADQ41426.1PFAM: peptidase M16 domain protein; KEGG: ate:Athe_0765 peptidase M16 domain protein. (424 aa)
ADQ41427.1KEGG: csc:Csac_0912 HI0074 family nucleotidyltransferase substrate binding protein; TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family; PFAM: Nucleotidyltransferase substrate binding protein HI0074. (133 aa)
ADQ41428.1PFAM: DNA polymerase beta domain protein region; KEGG: ate:Athe_0763 DNA polymerase beta domain protein region. (109 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (455 aa)
ADQ41950.1KEGG: ate:Athe_2648 penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase. (817 aa)
Your Current Organism:
Caldicellulosiruptor kristjanssonii
NCBI taxonomy Id: 632335
Other names: C. kristjanssonii I77R1B, Caldicellulosiruptor kristjanssonii DSM 12137, Caldicellulosiruptor kristjanssonii I77R1B, Caldicellulosiruptor kristjanssonii str. I77R1B, Caldicellulosiruptor kristjanssonii strain I77R1B
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