STRINGSTRING
murA murA ADQ39795.1 ADQ39795.1 murB murB ADQ39899.1 ADQ39899.1 ADQ40011.1 ADQ40011.1 ADQ40118.1 ADQ40118.1 murA-2 murA-2 glmU glmU ADQ40281.1 ADQ40281.1 ADQ40378.1 ADQ40378.1 ADQ40457.1 ADQ40457.1 galK galK ADQ40459.1 ADQ40459.1 ADQ40600.1 ADQ40600.1 ADQ40639.1 ADQ40639.1 ADQ40642.1 ADQ40642.1 ADQ40727.1 ADQ40727.1 ADQ40728.1 ADQ40728.1 ADQ40729.1 ADQ40729.1 ADQ40958.1 ADQ40958.1 murA-3 murA-3 glgC glgC ADQ41512.1 ADQ41512.1 ADQ41517.1 ADQ41517.1 ADQ41519.1 ADQ41519.1 ADQ41668.1 ADQ41668.1 ADQ41735.1 ADQ41735.1 glmS glmS glmM glmM ADQ41806.1 ADQ41806.1 ADQ41880.1 ADQ41880.1 ADQ41881.1 ADQ41881.1 fcl fcl gmd gmd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (414 aa)
ADQ39795.1PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; KEGG: ate:Athe_0233 nucleotidyl transferase. (710 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (314 aa)
ADQ39899.1KEGG: ate:Athe_0395 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II. (351 aa)
ADQ40011.1PFAM: PfkB domain protein; KEGG: ate:Athe_2118 PfkB domain protein. (307 aa)
ADQ40118.1TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS). (354 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (465 aa)
ADQ40281.1TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: ate:Athe_1946 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase. (385 aa)
ADQ40378.1TIGRFAM: nucleotide sugar dehydrogenase; KEGG: ate:Athe_1818 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (426 aa)
ADQ40457.1TIGRFAM: galactose-1-phosphate uridylyltransferase; KEGG: ate:Athe_0938 galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein. (333 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (389 aa)
ADQ40459.1KEGG: ate:Athe_0940 UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (327 aa)
ADQ40600.1Alpha-N-arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: ate:Athe_1103 alpha-N-arabinofuranosidase; SMART: alpha-L-arabinofuranosidase domain protein. (505 aa)
ADQ40639.1PFAM: NAD-dependent epimerase/dehydratase; KEGG: ate:Athe_1148 NAD-dependent epimerase/dehydratase. (305 aa)
ADQ40642.1KEGG: ate:Athe_1151 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. (302 aa)
ADQ40727.1TIGRFAM: nucleotide sugar dehydrogenase; KEGG: ate:Athe_1238 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (437 aa)
ADQ40728.1PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ate:Athe_1239 oxidoreductase domain protein. (374 aa)
ADQ40729.1KEGG: ate:Athe_1240 hexapaptide repeat-containing transferase. (246 aa)
ADQ40958.1KEGG: ate:Athe_1471 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; mannose-6-phosphate isomerase type II. (359 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (442 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (392 aa)
ADQ41512.1TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; KEGG: ate:Athe_0556 glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase. (380 aa)
ADQ41517.1PFAM: ROK family protein; KEGG: csc:Csac_0778 ROK family protein. (316 aa)
ADQ41519.1KEGG: ate:Athe_0096 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase. (380 aa)
ADQ41668.1PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; KEGG: ate:Athe_0459 glycosyltransferase 36. (790 aa)
ADQ41735.1PFAM: polysaccharide biosynthesis protein CapD; Polysaccharide biosynthesis domain protein; KEGG: slp:Slip_0163 polysaccharide biosynthesis protein CapD. (349 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (611 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa)
ADQ41806.1PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ate:Athe_2334 oxidoreductase domain protein. (366 aa)
ADQ41880.1PFAM: NAD-dependent epimerase/dehydratase; KEGG: mfe:Mefer_0524 NAD-dependent epimerase/dehydratase. (311 aa)
ADQ41881.1TIGRFAM: nucleotide sugar dehydrogenase; KEGG: msv:Mesil_2750 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (453 aa)
fclNAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (310 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (362 aa)
Your Current Organism:
Caldicellulosiruptor kristjanssonii
NCBI taxonomy Id: 632335
Other names: C. kristjanssonii I77R1B, Caldicellulosiruptor kristjanssonii DSM 12137, Caldicellulosiruptor kristjanssonii I77R1B, Caldicellulosiruptor kristjanssonii str. I77R1B, Caldicellulosiruptor kristjanssonii strain I77R1B
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.