STRINGSTRING
ftsH ftsH mnmE mnmE ADQ05752.1 ADQ05752.1 recD2 recD2 ADQ05691.1 ADQ05691.1 ADQ05687.1 ADQ05687.1 ADQ05686.1 ADQ05686.1 ADQ05680.1 ADQ05680.1 ADQ05675.1 ADQ05675.1 ADQ05671.1 ADQ05671.1 ADQ05654.1 ADQ05654.1 ADQ05371.1 ADQ05371.1 bioD bioD ADQ05604.1 ADQ05604.1 ADQ05591.1 ADQ05591.1 ADQ05588.1 ADQ05588.1 ADQ05556.1 ADQ05556.1 ADQ05555.1 ADQ05555.1 ADQ05538.1 ADQ05538.1 macB macB ADQ05506.1 ADQ05506.1 ADQ05494.1 ADQ05494.1 ADQ05478.1 ADQ05478.1 rbsA rbsA ADQ05463.1 ADQ05463.1 fhs fhs ADQ05409.1 ADQ05409.1 ADQ05407.1 ADQ05407.1 hslU hslU ADQ05389.1 ADQ05389.1 dnaA dnaA recF recF purA purA ADQ03639.1 ADQ03639.1 ADQ03640.1 ADQ03640.1 pyrG pyrG xylG xylG ADQ03676.1 ADQ03676.1 ADQ03682.1 ADQ03682.1 ADQ03744.1 ADQ03744.1 ADQ03745.1 ADQ03745.1 ADQ03749.1 ADQ03749.1 ADQ03780.1 ADQ03780.1 ADQ03781.1 ADQ03781.1 ADQ03793.1 ADQ03793.1 ADQ03800.1 ADQ03800.1 ADQ03823.1 ADQ03823.1 ADQ03824.1 ADQ03824.1 hprK hprK ADQ03878.1 ADQ03878.1 ADQ03913.1 ADQ03913.1 ADQ03924.1 ADQ03924.1 ADQ03930.1 ADQ03930.1 tmk tmk ADQ03958.1 ADQ03958.1 ADQ03972.1 ADQ03972.1 mfd mfd clpX clpX ADQ04166.1 ADQ04166.1 der der fusA fusA tuf tuf hflX hflX ADQ04249.1 ADQ04249.1 ADQ04283.1 ADQ04283.1 ADQ04294.1 ADQ04294.1 lon lon engB engB ffh ffh ADQ04327.1 ADQ04327.1 ADQ04334.1 ADQ04334.1 recA recA ADQ04344.1 ADQ04344.1 ADQ04387.1 ADQ04387.1 ADQ04395.1 ADQ04395.1 gmk gmk priA priA rsgA rsgA infB infB ADQ04446.1 ADQ04446.1 rho rho ADQ04474.1 ADQ04474.1 ADQ04479.1 ADQ04479.1 ruvB ruvB obg obg rgy rgy ADQ04519.1 ADQ04519.1 ADQ04521.1 ADQ04521.1 smc smc ftsY ftsY recG recG ADQ04626.1 ADQ04626.1 ADQ04639.1 ADQ04639.1 ADQ04660.1 ADQ04660.1 cmk cmk ADQ04689.1 ADQ04689.1 ADQ04729.1 ADQ04729.1 ADQ04730.1 ADQ04730.1 era era atpD atpD atpA atpA uvrA uvrA uvrB uvrB coaE coaE pstB pstB miaA miaA mutS mutS clpB clpB ADQ04852.1 ADQ04852.1 ADQ04854.1 ADQ04854.1 ADQ04858.1 ADQ04858.1 ADQ04859.1 ADQ04859.1 lepA lepA ADQ04898.1 ADQ04898.1 ADQ04903.1 ADQ04903.1 ADQ04906.1 ADQ04906.1 ADQ04909.1 ADQ04909.1 ychF ychF mutS2 mutS2 ADQ04959.1 ADQ04959.1 ecfA ecfA ecfA-2 ecfA-2 aroK aroK ADQ04995.1 ADQ04995.1 adk adk ADQ05070.1 ADQ05070.1 ftsE ftsE ADQ05094.1 ADQ05094.1 ADQ05115.1 ADQ05115.1 ADQ05121.1 ADQ05121.1 ADQ05134.1 ADQ05134.1 ADQ05148.1 ADQ05148.1 ADQ05149.1 ADQ05149.1 ADQ05156.1 ADQ05156.1 ADQ05176.1 ADQ05176.1 ADQ05177.1 ADQ05177.1 ADQ05182.1 ADQ05182.1 ADQ05196.1 ADQ05196.1 ADQ05208.1 ADQ05208.1 ADQ05270.1 ADQ05270.1 radA radA secA secA dnaX dnaX ADQ05370.1 ADQ05370.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (616 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa)
ADQ05752.1KEGG: ate:Athe_2752 cobyrinic acid ac-diamide synthase. (263 aa)
recD2Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (741 aa)
ADQ05691.1KEGG: csc:Csac_0515 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (321 aa)
ADQ05687.1KEGG: ate:Athe_2619 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (578 aa)
ADQ05686.1KEGG: ate:Athe_2618 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (612 aa)
ADQ05680.1KEGG: ate:Athe_2608 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (246 aa)
ADQ05675.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (491 aa)
ADQ05671.1PFAM: DUF234 DEXX-box ATPase; KEGG: csc:Csac_0072 ATPase. (460 aa)
ADQ05654.1PFAM: ATPase associated with various cellular activities AAA_3; KEGG: ate:Athe_2560 ATPase associated with various cellular activities AAA_3. (315 aa)
ADQ05371.1TIGRFAM: flagellar biosynthetic protein FlhF; PFAM: GTP-binding signal recognition particle SRP54 G- domain; KEGG: ate:Athe_2152 GTP-binding signal recognition particle SRP54 G-domain protein; SMART: AAA ATPase. (371 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (243 aa)
ADQ05604.1KEGG: csc:Csac_0366 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (317 aa)
ADQ05591.1KEGG: ate:Athe_2351 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (230 aa)
ADQ05588.1KEGG: ate:Athe_2348 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (306 aa)
ADQ05556.1Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1033 aa)
ADQ05555.1PFAM: SMC domain protein; KEGG: tit:Thit_1894 SMC domain protein. (658 aa)
ADQ05538.1KEGG: tit:Thit_1875 Tn7-like transposition protein C. (553 aa)
macBABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (241 aa)
ADQ05506.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (263 aa)
ADQ05494.1KEGG: dae:Dtox_4107 capsular exopolysaccharide family; TIGRFAM: capsular exopolysaccharide family. (257 aa)
ADQ05478.1KEGG: csc:Csac_0238 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (491 aa)
rbsAABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (499 aa)
ADQ05463.1PFAM: Dynamin family protein; KEGG: ate:Athe_2259 dynamin family protein. (589 aa)
fhsKEGG: ate:Athe_2208 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS. (553 aa)
ADQ05409.1TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; KEGG: ate:Athe_2193 Mg chelatase, subunit ChlI; SMART: AAA ATPase. (510 aa)
ADQ05407.1KEGG: ate:Athe_2191 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (255 aa)
hslUHeat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (464 aa)
ADQ05389.1TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; KEGG: ate:Athe_2170 ATPase, FliI/YscN family; SMART: AAA ATPase. (434 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (454 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (353 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (426 aa)
ADQ03639.1KEGG: ate:Athe_0047 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (580 aa)
ADQ03640.1KEGG: ate:Athe_0048 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (598 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (541 aa)
xylGABC transporter related protein; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (505 aa)
ADQ03676.1KEGG: ate:Athe_0113 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (241 aa)
ADQ03682.1TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; KEGG: csc:Csac_0317 CRISPR-associated helicase Cas3; SMART: helicase domain protein; DEAD-like helicase. (914 aa)
ADQ03744.1KEGG: ate:Athe_0202 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (742 aa)
ADQ03745.1KEGG: ate:Athe_0203 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (628 aa)
ADQ03749.1KEGG: csc:Csac_2030 phosphate ABC transporter, ATPase subunit. (72 aa)
ADQ03780.1KEGG: dth:DICTH_1544 putative ABC-transporter TycD; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (579 aa)
ADQ03781.1KEGG: dth:DICTH_1543 multidrug resistance ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (598 aa)
ADQ03793.1KEGG: ate:Athe_0249 chromosome segregation ATPase-like protein. (1350 aa)
ADQ03800.1KEGG: csc:Csac_0175 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (254 aa)
ADQ03823.1KEGG: ate:Athe_0339 hypothetical protein. (875 aa)
ADQ03824.1UvrD/REP helicase; ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (955 aa)
hprKHPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] (311 aa)
ADQ03878.1PFAM: Uncharacterised protein family UPF0079, ATPase; KEGG: ate:Athe_0444 protein of unknown function UPF0079. (157 aa)
ADQ03913.1KEGG: cro:ROD_05841 putative sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (510 aa)
ADQ03924.1KEGG: csc:Csac_1116 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (586 aa)
ADQ03930.1KEGG: csc:Csac_1123 small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related. (403 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa)
ADQ03958.1KEGG: ate:Athe_0515 DNA-directed DNA polymerase. (320 aa)
ADQ03972.1SMART: AAA ATPase; KEGG: ate:Athe_0531 AAA ATPase. (554 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1141 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (433 aa)
ADQ04166.1KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein. (616 aa)
derRibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (440 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (691 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (400 aa)
hflXGTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (509 aa)
ADQ04249.1KEGG: ate:Athe_0826 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (195 aa)
ADQ04283.1KEGG: ate:Athe_0860 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (249 aa)
ADQ04294.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (447 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (775 aa)
engBRibosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (204 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (443 aa)
ADQ04327.1Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (282 aa)
ADQ04334.1Manually curated; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; KEGG: ate:Athe_0980 cell divisionFtsK/SpoIIIE; SMART: AAA ATPase. (746 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (356 aa)
ADQ04344.1SMART: AAA ATPase; KEGG: ate:Athe_0990 AAA ATPase. (313 aa)
ADQ04387.1AAA ATPase; KEGG: tit:Thit_1404 AAA ATPase; manually curated; SMART: AAA ATPase. (266 aa)
ADQ04395.1TIGRFAM: phage terminase, large subunit, PBSX family; KEGG: ctc:CTC01086 phage terminase large subunit. (404 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (724 aa)
rsgARibosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (290 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (831 aa)
ADQ04446.1KEGG: ate:Athe_1061 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase. (441 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (556 aa)
ADQ04474.1KEGG: ate:Athe_1089 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K. (220 aa)
ADQ04479.1KEGG: ate:Athe_1094 hypothetical protein. (229 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (338 aa)
obgGTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (427 aa)
rgyReverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1122 aa)
ADQ04519.1KEGG: ate:Athe_1140 protein of unknown function DUF87. (554 aa)
ADQ04521.1PFAM: SMC domain protein; KEGG: ate:Athe_1142 SMC domain protein. (857 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1177 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (301 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (679 aa)
ADQ04626.1PFAM: PhoH family protein; K Homology, type 1, subgroup; KEGG: ate:Athe_1272 PhoH family protein. (325 aa)
ADQ04639.1PFAM: UvrD/REP helicase; KEGG: ate:Athe_1285 UvrD/REP helicase. (714 aa)
ADQ04660.1TIGRFAM: septum site-determining protein MinD; KEGG: ate:Athe_1306 septum site-determining protein MinD. (266 aa)
cmkKEGG: ate:Athe_1325 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase. (226 aa)
ADQ04689.1DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (551 aa)
ADQ04729.1KEGG: ate:Athe_1384 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (234 aa)
ADQ04730.1KEGG: ate:Athe_1385 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (256 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (300 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (467 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (507 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (952 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (661 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (199 aa)
pstBPhosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (249 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (312 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (863 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (864 aa)
ADQ04852.1KEGG: ate:Athe_1519 peptidase S16, lon-like protein. (787 aa)
ADQ04854.1KEGG: ate:Athe_1521 hypothetical protein. (269 aa)
ADQ04858.1KEGG: ate:Athe_1525 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (581 aa)
ADQ04859.1KEGG: ate:Athe_1526 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (597 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (602 aa)
ADQ04898.1Small GTP-binding protein; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (609 aa)
ADQ04903.1KEGG: ate:Athe_1583 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (232 aa)
ADQ04906.1KEGG: ate:Athe_1586 protein of unknown function DUF815; PFAM: protein of unknown function DUF815; SMART: AAA ATPase. (440 aa)
ADQ04909.1PFAM: Circadian clock protein KaiC central region; KEGG: ate:Athe_1613 putative circadian clock protein, KaiC. (312 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (362 aa)
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (786 aa)
ADQ04959.1KEGG: ate:Athe_1666 AAA family ATPase. (476 aa)
ecfAABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (290 aa)
ecfA-2ABC transporter related protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (278 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (172 aa)
ADQ04995.1KEGG: csc:Csac_2246 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (312 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
ADQ05070.1KEGG: ate:Athe_1781 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (503 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (239 aa)
ADQ05094.1KEGG: csc:Csac_2346 ABC transporter related; PFAM: ABC transporter related; TOBE domain-containing protein; SMART: AAA ATPase. (370 aa)
ADQ05115.1KEGG: ate:Athe_1825 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. (829 aa)
ADQ05121.1KEGG: ate:Athe_1831 translation elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein. (694 aa)
ADQ05134.1KEGG: ate:Athe_1844 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide TPR_1 repeat-containing protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide repeat. (1148 aa)
ADQ05148.1TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: csc:Csac_1061 twitching motility protein; SMART: AAA ATPase. (351 aa)
ADQ05149.1KEGG: csc:Csac_1060 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase. (565 aa)
ADQ05156.1KEGG: ate:Athe_1894 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (408 aa)
ADQ05176.1TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: ate:Athe_1914 oligopeptide/dipeptide ABC transporter, ATPase subunit; SMART: AAA ATPase. (321 aa)
ADQ05177.1TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: ate:Athe_1915 oligopeptide/dipeptide ABC transporter, ATPase subunit; SMART: AAA ATPase. (338 aa)
ADQ05182.1KEGG: ate:Athe_1920 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. (335 aa)
ADQ05196.1KEGG: str:Sterm_4203 DnaB domain protein helicase domain protein; PFAM: DnaB domain protein helicase domain protein; TOPRIM domain-containing protein; SMART: Toprim sub domain-containing protein. (607 aa)
ADQ05208.1KEGG: ate:Athe_1940 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (261 aa)
ADQ05270.1SMART: AAA ATPase; KEGG: ate:Athe_2046 AAA ATPase. (342 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (446 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (848 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (534 aa)
ADQ05370.1KEGG: ate:Athe_2151 cobyrinic acid ac-diamide synthase. (298 aa)
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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