36 items (Thalassobium sp. R2A62) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gshB	Glutathione synthase; Identified by match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM PF08443; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (312 aa)
	EET48192.1	Glutathione S-transferase family protein. (152 aa)
	EET49523.1	Cation transport protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (178 aa)
	gnd	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (467 aa)
	EET47839.1	Identified by match to protein family HMM PF00883; match to protein family HMM PF02789; Belongs to the peptidase M17 family. (461 aa)
	grxC	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (85 aa)
	EET49606.1	Glutathione S-transferase, C- domain; Identified by match to protein family HMM PF02798. (212 aa)
	EET46453.1	Identified by match to protein family HMM PF02798. (225 aa)
	EET49315.1	Glutaredoxin; Identified by match to protein family HMM PF00043; match to protein family HMM PF02798. (208 aa)
	EET48296.1	Identified by match to protein family HMM PF01019; gamma-glutamyltransferase 2. threonine peptidase. merops family t03. (525 aa)
	EET48993.1	Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (456 aa)
	EET47902.1	Conserved hypothetical protein; Identified by match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family. (185 aa)
	EET46919.1	Glutathione S-transferase, N-terminal domain protein; Identified by match to protein family HMM PF02798; Belongs to the GST superfamily. (285 aa)
	EET46310.1	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily. (232 aa)
	EET49269.1	Allophanate hydrolase subunit 1; Identified by match to protein family HMM PF02682. (250 aa)
	EET47604.1	Allophanate hydrolase subunit 2; Identified by match to protein family HMM PF02626. (336 aa)
	pxpA	LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (259 aa)
	EET48918.1	Conserved hypothetical protein. (313 aa)
	EET47835.1	Conserved hypothetical protein. (66 aa)
	EET48683.1	Identified by match to protein family HMM PF02798. (230 aa)
	EET47641.1	Glutathione reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992. (468 aa)
	EET49723.1	Membrane-associated protein in eicosanoid and glutathione metabolism. (128 aa)
	pepN	Identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414. (909 aa)
	pepA	Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (488 aa)
	EET48247.1	Conserved hypothetical protein. (254 aa)
	EET48182.1	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
	zwf	Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (484 aa)
	EET46608.1	Peptidoglycan binding domain protein. (289 aa)
	EET48823.1	Peptidoglycan binding domain protein. (120 aa)
	EET47661.1	Glutathione S-transferase, N- domain protein; Identified by match to protein family HMM PF02798. (217 aa)
	EET47923.1	Conserved hypothetical protein. (138 aa)
	EET49492.1	Glutathione S-transferase domain protein; Identified by match to protein family HMM PF00043; match to protein family HMM PF02798. (231 aa)
	EET49344.1	Conserved hypothetical protein; Identified by match to protein family HMM PF06108. (107 aa)
	EET46762.1	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily. (210 aa)
	EET48092.1	Hybrid peroxiredoxin hyPrx5; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (162 aa)
	EET46891.1	Identified by match to protein family HMM PF01968; match to protein family HMM PF05378. (701 aa)

Your Current Organism:

Thalassobium sp. R2A62

NCBI taxonomy Id: 633131
Other names: T. sp. R2A62, Thalassiobium sp. R2A62, alpha proteobacterium R2A62

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EET46310.1	EET46453.1	TR2A62_2133	TR2A62_2459	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Identified by match to protein family HMM PF02798.	0.473
EET46310.1	EET48092.1	TR2A62_2133	TR2A62_2891	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Hybrid peroxiredoxin hyPrx5; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.448
EET46310.1	EET48192.1	TR2A62_2133	TR2A62_3242	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Glutathione S-transferase family protein.	0.427
EET46453.1	EET46310.1	TR2A62_2459	TR2A62_2133	Identified by match to protein family HMM PF02798.	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	0.473
EET46453.1	EET47641.1	TR2A62_2459	TR2A62_1310	Identified by match to protein family HMM PF02798.	Glutathione reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.	0.874
EET46453.1	EET47661.1	TR2A62_2459	TR2A62_0303	Identified by match to protein family HMM PF02798.	Glutathione S-transferase, N- domain protein; Identified by match to protein family HMM PF02798.	0.603
EET46453.1	EET48092.1	TR2A62_2459	TR2A62_2891	Identified by match to protein family HMM PF02798.	Hybrid peroxiredoxin hyPrx5; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.859
EET46453.1	EET48296.1	TR2A62_2459	TR2A62_2338	Identified by match to protein family HMM PF02798.	Identified by match to protein family HMM PF01019; gamma-glutamyltransferase 2. threonine peptidase. merops family t03.	0.859
EET46453.1	EET48683.1	TR2A62_2459	TR2A62_1314	Identified by match to protein family HMM PF02798.	Identified by match to protein family HMM PF02798.	0.738
EET46453.1	EET49315.1	TR2A62_2459	TR2A62_2422	Identified by match to protein family HMM PF02798.	Glutaredoxin; Identified by match to protein family HMM PF00043; match to protein family HMM PF02798.	0.875
EET46453.1	EET49492.1	TR2A62_2459	TR2A62_0011	Identified by match to protein family HMM PF02798.	Glutathione S-transferase domain protein; Identified by match to protein family HMM PF00043; match to protein family HMM PF02798.	0.475
EET46453.1	EET49523.1	TR2A62_2459	TR2A62_3296	Identified by match to protein family HMM PF02798.	Cation transport protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.883
EET46453.1	EET49606.1	TR2A62_2459	TR2A62_2497	Identified by match to protein family HMM PF02798.	Glutathione S-transferase, C- domain; Identified by match to protein family HMM PF02798.	0.757
EET46453.1	grxC	TR2A62_2459	TR2A62_2561	Identified by match to protein family HMM PF02798.	Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.	0.467
EET46453.1	gshB	TR2A62_2459	TR2A62_3200	Identified by match to protein family HMM PF02798.	Glutathione synthase; Identified by match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM PF08443; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family.	0.911
EET46608.1	EET48823.1	TR2A62_0367	TR2A62_0366	Peptidoglycan binding domain protein.	Peptidoglycan binding domain protein.	0.993
EET46762.1	EET47641.1	TR2A62_3442	TR2A62_1310	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Glutathione reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.	0.879
EET46762.1	EET48092.1	TR2A62_3442	TR2A62_2891	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Hybrid peroxiredoxin hyPrx5; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.859
EET46762.1	EET48296.1	TR2A62_3442	TR2A62_2338	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Identified by match to protein family HMM PF01019; gamma-glutamyltransferase 2. threonine peptidase. merops family t03.	0.859
EET46762.1	EET48683.1	TR2A62_3442	TR2A62_1314	Identified by match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.	Identified by match to protein family HMM PF02798.	0.800