STRINGSTRING
Tagg_0192 Tagg_0192 Tagg_0735 Tagg_0735 Tagg_1237 Tagg_1237 Tagg_0553 Tagg_0553 Tagg_0486 Tagg_0486 mvk mvk Tagg_1183 Tagg_1183 Tagg_1157 Tagg_1157 nadK nadK Tagg_0970 Tagg_0970 Tagg_0777 Tagg_0777 thiM thiM Tagg_0106 Tagg_0106 Tagg_0132 Tagg_0132 Tagg_1369 Tagg_1369
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tagg_0192COGs: COG0478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain; InterProIPR015285:IPR018934:IPR000687:IPR008266:IPR 000719; KEGG: similar to S. cerevisiae YNL207W; K07179 RIO kinase 2; PFAM: RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART: protein of unknown function RIO1; SPTR: A3DP27 Putative uncharacterized protein; PFAM: RIO1 family; Rio2, N-terminal. (292 aa)
Tagg_0735PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611; KEGG: hiq:CGSHiGG_05785 ribokinase; PFAM: PfkB domain protein; SPTR: A3DLR5 PfkB domain protein; PFAM: pfkB family carbohydrate kinase. (315 aa)
Tagg_1237COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR001697; KEGG: nis:NIS_1773 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: A3DMY9 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (467 aa)
Tagg_0553COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611:IPR002173; KEGG: gbm:Gbem_2483 PfkB domain protein; PFAM: PfkB domain protein; SPTR: B8D4B0 ATP-dependent 6-phosphofructokinase; PFAM: pfkB family carbohydrate kinase. (306 aa)
Tagg_0486ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600:IPR006025; KEGG: rlt:Rleg2_5489 ROK family protein; PFAM: ROK family protein; SPTR: B8D441 Glucokinase (ROK family protein); PFAM: ROK family. (322 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (307 aa)
Tagg_1183ATP-NAD/AcoX kinase; COGs: COG3199 conserved hypothetical protein; InterPro IPR002504; KEGG: cja:CJA_2375 NAD(+)/NADH kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: B8D5H1 ATP-NAD/AcoX kinase; PFAM: ATP-NAD kinase. (377 aa)
Tagg_1157COGs: COG1341 GTPase or GTP-binding protein; KEGG: Nol9; nucleolar protein 9; SPTR: B8D2S7 Putative GTPase or GTP-binding protein; PFAM: Molybdopterin guanine dinucleotide synthesis protein B. (416 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa)
Tagg_0970RIO-like kinase; COGs: COG1718 Serine/threonine protein kinase involved in cell cycle control; InterPro IPR018934:IPR000687:IPR000719:IPR018935; KEGG: RIO1 family protein (EC:2.7.11.1); K07178 RIO kinase 1; PFAM: RIO-like kinase; SMART: protein of unknown function RIO1; SPTR: B8D5N2 Putative kinase; PFAM: RIO1 family. (270 aa)
Tagg_0777Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004399; KEGG: sfu:Sfum_1692 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: B8D4K9 Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (290 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (274 aa)
Tagg_0106Protein of unknown function DUF120; COGs: COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon; InterPro IPR002834; KEGG: eba:ebA3131 hypothetical protein; PFAM: protein of unknown function DUF120; SPTR: B8D5C1 Riboflavin kinase; PFAM: Domain of unknown function DUF120. (143 aa)
Tagg_0132COGs: COG2112 Ser/Thr protein kinase; SPTR: B8D3G5 Ser/Thr protein kinase-like protein. (253 aa)
Tagg_1369COGs: COG3642 Mn2+-dependent serine/threonine protein kinase; InterPro IPR018934:IPR002575:IPR002290:IPR000719; KEGG: hypothetical protein; K08851 TP53 regulating kinase; PFAM: RIO-like kinase; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; SPTR: B8D6D5 Mn2+-dependent serine/threonine protein kinase; PFAM: RIO1 family. (225 aa)
Your Current Organism:
Thermosphaera aggregans
NCBI taxonomy Id: 633148
Other names: T. aggregans DSM 11486, Thermosphaera aggregans DSM 11486, Thermosphaera aggregans M11TL, Thermosphaera aggregans str. DSM 11486, Thermosphaera aggregans strain DSM 11486
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