(16 nodes) Tricarboxylic acid cycle network (Trichinella nelsoni)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	T07_14715	PDZ domain-containing protein. (154 aa)
	T01C8.5	Aspartate aminotransferase. (403 aa)
	SUCLA2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (450 aa)
	idha-1	Putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial. (424 aa)
	IDH2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (433 aa)
	dlst	annotation not available (534 aa)
	T07_15135	2-oxoglutarate dehydrogenase, mitochondrial. (1189 aa)
	got2	Aspartate aminotransferase. (422 aa)
	mev-1	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (185 aa)
	sdhd-1	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (185 aa)
	sdhb-1	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (680 aa)
	idhb-1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
	aco-2	Putative aconitate hydratase, mitochondrial. (2164 aa)
	sdha-1	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (863 aa)
	T07_330	RING-type domain-containing protein. (502 aa)
	Fh	Fumarate hydratase, mitochondrial. (508 aa)

Your Current Organism:

Trichinella nelsoni

NCBI taxonomy Id: 6336
Other names: T. nelsoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fh	IDH2	A0A0V0SNM5	A0A0V0RQS6	Fumarate hydratase, mitochondrial.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.945
Fh	SUCLA2	A0A0V0SNM5	A0A0V0RN87	Fumarate hydratase, mitochondrial.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.925
Fh	T01C8.5	A0A0V0SNM5	A0A0V0RG81	Fumarate hydratase, mitochondrial.	Aspartate aminotransferase.	0.922
Fh	T07_14715	A0A0V0SNM5	A0A0V0RG35	Fumarate hydratase, mitochondrial.	PDZ domain-containing protein.	0.963
Fh	T07_15135	A0A0V0SNM5	A0A0V0RWW5	Fumarate hydratase, mitochondrial.	2-oxoglutarate dehydrogenase, mitochondrial.	0.949
Fh	T07_330	A0A0V0SNM5	A0A0V0SGS9	Fumarate hydratase, mitochondrial.	RING-type domain-containing protein.	0.924
Fh	aco-2	A0A0V0SNM5	A0A0V0SEG8	Fumarate hydratase, mitochondrial.	Putative aconitate hydratase, mitochondrial.	0.847
Fh	dlst	A0A0V0SNM5	A0A0V0RUC1	Fumarate hydratase, mitochondrial.	annotation not available	0.819
Fh	got2	A0A0V0SNM5	A0A0V0S074	Fumarate hydratase, mitochondrial.	Aspartate aminotransferase.	0.945
Fh	idha-1	A0A0V0SNM5	A0A0V0RNM2	Fumarate hydratase, mitochondrial.	Putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial.	0.797
Fh	idhb-1	A0A0V0SNM5	A0A0V0SCF0	Fumarate hydratase, mitochondrial.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.821
Fh	mev-1	A0A0V0SNM5	A0A0V0S385	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial.	0.982
Fh	sdha-1	A0A0V0SNM5	A0A0V0SEZ5	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.997
Fh	sdhb-1	A0A0V0SNM5	A0A0V0S8R7	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.974
Fh	sdhd-1	A0A0V0SNM5	A0A0V0S3K8	Fumarate hydratase, mitochondrial.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.980
IDH2	Fh	A0A0V0RQS6	A0A0V0SNM5	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Fumarate hydratase, mitochondrial.	0.945
IDH2	SUCLA2	A0A0V0RQS6	A0A0V0RN87	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.938
IDH2	T01C8.5	A0A0V0RQS6	A0A0V0RG81	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Aspartate aminotransferase.	0.930
IDH2	T07_14715	A0A0V0RQS6	A0A0V0RG35	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	PDZ domain-containing protein.	0.992
IDH2	T07_15135	A0A0V0RQS6	A0A0V0RWW5	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	2-oxoglutarate dehydrogenase, mitochondrial.	0.989