(32 nodes) Pyruvate metabolism and Citric Acid (TCA) cycle network (Trichinella nelsoni)

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Your Input:
	C04C3.3	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (362 aa)
	MDHG	Malate dehydrogenase, glyoxysomal. (52 aa)
	T07_14715	PDZ domain-containing protein. (154 aa)
	T05H10.6	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (427 aa)
	YNG2	Chromatin modification-related protein YNG2. (305 aa)
	F42A8.1	Uncharacterized protein. (356 aa)
	SUCLA2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (450 aa)
	idha-1	Putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial. (424 aa)
	Glo1	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (190 aa)
	pdhk-2	Protein-serine/threonine kinase. (416 aa)
	dlst	annotation not available (534 aa)
	T07_11760	L-2-hydroxyglutarate dehydrogenase, mitochondrial. (511 aa)
	T07_15135	2-oxoglutarate dehydrogenase, mitochondrial. (1189 aa)
	mev-1	Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (185 aa)
	T05H10.6-2	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (411 aa)
	sdhd-1	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (185 aa)
	dld-1	Dihydrolipoyl dehydrogenase. (528 aa)
	MPC2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (491 aa)
	sdhb-1	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (680 aa)
	Pdhx	Pyruvate dehydrogenase protein X component, mitochondrial. (312 aa)
	ME1	Malic enzyme. (592 aa)
	NNT	NAD(P) transhydrogenase, mitochondrial. (1070 aa)
	ldh-1	L-lactate dehydrogenase. (415 aa)
	F42A8.1-2	Uncharacterized protein. (364 aa)
	idhb-1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
	F23B12.5	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (558 aa)
	aco-2	Putative aconitate hydratase, mitochondrial. (2164 aa)
	sdha-1	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (863 aa)
	T07_330	RING-type domain-containing protein. (502 aa)
	Me3	Malic enzyme; Belongs to the malic enzymes family. (1256 aa)
	fahd1	Acylpyruvase FAHD1, mitochondrial. (218 aa)
	Fh	Fumarate hydratase, mitochondrial. (508 aa)

Your Current Organism:

Trichinella nelsoni

NCBI taxonomy Id: 6336
Other names: T. nelsoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C04C3.3	F23B12.5	A0A0V0S4I2	A0A0V0SD41	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
C04C3.3	F42A8.1	A0A0V0S4I2	A0A0V0RMH2	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Uncharacterized protein.	0.631
C04C3.3	F42A8.1-2	A0A0V0S4I2	A0A0V0SC76	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Uncharacterized protein.	0.631
C04C3.3	Fh	A0A0V0S4I2	A0A0V0SNM5	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Fumarate hydratase, mitochondrial.	0.597
C04C3.3	MDHG	A0A0V0S4I2	A0A0V0RAC2	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Malate dehydrogenase, glyoxysomal.	0.756
C04C3.3	ME1	A0A0V0S4I2	A0A0V0SAK5	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Malic enzyme.	0.944
C04C3.3	Me3	A0A0V0S4I2	A0A0V0SKY6	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Malic enzyme; Belongs to the malic enzymes family.	0.895
C04C3.3	Pdhx	A0A0V0S4I2	A0A0V0S917	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase protein X component, mitochondrial.	0.993
C04C3.3	SUCLA2	A0A0V0S4I2	A0A0V0RN87	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.907
C04C3.3	T05H10.6	A0A0V0S4I2	A0A0V0RJ25	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
C04C3.3	T05H10.6-2	A0A0V0S4I2	A0A0V0S3H4	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
C04C3.3	T07_14715	A0A0V0S4I2	A0A0V0RG35	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	PDZ domain-containing protein.	0.940
C04C3.3	T07_15135	A0A0V0S4I2	A0A0V0RWW5	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	2-oxoglutarate dehydrogenase, mitochondrial.	0.929
C04C3.3	T07_330	A0A0V0S4I2	A0A0V0SGS9	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	RING-type domain-containing protein.	0.756
C04C3.3	aco-2	A0A0V0S4I2	A0A0V0SEG8	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Putative aconitate hydratase, mitochondrial.	0.702
C04C3.3	dld-1	A0A0V0S4I2	A0A0V0S4P8	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Dihydrolipoyl dehydrogenase.	0.999
C04C3.3	dlst	A0A0V0S4I2	A0A0V0RUC1	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	annotation not available	0.975
C04C3.3	idha-1	A0A0V0S4I2	A0A0V0RNM2	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial.	0.790
C04C3.3	idhb-1	A0A0V0S4I2	A0A0V0SCF0	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.755
C04C3.3	ldh-1	A0A0V0S4I2	A0A0V0SBV7	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	L-lactate dehydrogenase.	0.878