STRINGSTRING
Brca2 Brca2 Top3b Top3b T07_2980 T07_2980 CYP10 CYP10 Mcfd2 Mcfd2 unc-93 unc-93 Atrx Atrx INO80 INO80 Ccdc94 Ccdc94 Brip1-2 Brip1-2 prkrip1 prkrip1 RECQL5 RECQL5 RPA1 RPA1 Brip1 Brip1 sas6 sas6 rtel1 rtel1 BRE BRE BRCA1 BRCA1 unc93a unc93a RAD54L RAD54L Ddx52 Ddx52 TOP3A TOP3A T07_5803 T07_5803 T07_10447 T07_10447 rbbp8 rbbp8 pold2 pold2 Topbp1 Topbp1 Rpa2 Rpa2 RAD51 RAD51
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Brca2Breast cancer type 2 susceptibility-like protein. (1238 aa)
Top3bDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (904 aa)
T07_2980Uncharacterized protein. (793 aa)
CYP10Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (179 aa)
Mcfd2Multiple coagulation factor deficiency protein 2-like protein. (138 aa)
unc-93Putative potassium channel regulatory protein unc-93. (646 aa)
AtrxTranscriptional regulator ATRX-like protein. (1585 aa)
INO80DNA helicase INO80. (328 aa)
Ccdc94Coiled-coil domain-containing protein 94. (298 aa)
Brip1-2Fanconi anemia group J-like protein. (818 aa)
prkrip1PRKR-interacting protein 1-like protein. (213 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (843 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (660 aa)
Brip1Fanconi anemia group J-like protein. (847 aa)
sas6Spindle assembly abnormal protein 6-like protein. (523 aa)
rtel1Regulator of telomere elongation helicase 1. (1037 aa)
BREBRCA1-A complex subunit BRE. (439 aa)
BRCA1Breast cancer type 1 susceptibility-like protein. (367 aa)
unc93aProtein unc-93-like protein A. (462 aa)
RAD54LDNA repair and recombination protein RAD54-like. (748 aa)
Ddx52Putative ATP-dependent RNA helicase DDX52. (589 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (870 aa)
T07_5803Uncharacterized protein. (128 aa)
T07_10447DNA polymerase. (1131 aa)
rbbp8DNA endonuclease RBBP8. (259 aa)
pold2DNA polymerase delta subunit 2. (474 aa)
Topbp1DNA topoisomerase 2-binding protein 1. (1405 aa)
Rpa2Replication protein A 32 kDa subunit. (267 aa)
RAD51DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (387 aa)
Your Current Organism:
Trichinella nelsoni
NCBI taxonomy Id: 6336
Other names: T. nelsoni
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