STRINGSTRING
Brca1 Brca1 unc93a unc93a Mcfd2 Mcfd2 rbbp8 rbbp8 prkrip1 prkrip1 Brip1-2 Brip1-2 sas6 sas6 XNP XNP Brca2 Brca2 T4E_8866 T4E_8866 Top3b Top3b RAD51 RAD51 RPA2 RPA2 Brip1 Brip1 Top3a Top3a TOP3A TOP3A Top3alpha Top3alpha T4E_5521 T4E_5521 T4E_4237 T4E_4237 Shf Shf unc-93-2 unc-93-2 mus81-2 mus81-2 EME1 EME1 Rad51d Rad51d MRE11A MRE11A T4E_10094 T4E_10094 T4E_4003 T4E_4003 CYP10 CYP10 pold2 pold2 tmc-2 tmc-2 RECQL5 RECQL5 PPP1R21 PPP1R21 Ddx52 Ddx52 Topbp1 Topbp1 RAD54L RAD54L him-6 him-6 T4E_3040 T4E_3040 RAD51C RAD51C RPA1 RPA1 mus81 mus81 mus309 mus309 unc-93 unc-93
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Brca1Breast cancer type 1 susceptibility-like protein. (318 aa)
unc93aProtein unc-93-like protein A. (462 aa)
Mcfd2Multiple coagulation factor deficiency protein 2-like protein. (137 aa)
rbbp8DNA endonuclease RBBP8. (225 aa)
prkrip1PRKR-interacting protein 1-like protein. (122 aa)
Brip1-2Fanconi anemia group J-like protein. (822 aa)
sas6Spindle assembly abnormal protein 6-like protein. (478 aa)
XNPTranscriptional regulator ATRX-like protein. (1513 aa)
Brca2Breast cancer type 2 susceptibility-like protein. (1238 aa)
T4E_8866Uncharacterized protein. (687 aa)
Top3bDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (860 aa)
RAD51DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (363 aa)
RPA2Replication protein A 32 kDa subunit. (269 aa)
Brip1Fanconi anemia group J-like protein. (847 aa)
Top3aDNA topoisomerase 3-alpha. (324 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (321 aa)
Top3alphaDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (232 aa)
T4E_5521DNA polymerase delta catalytic subunit. (516 aa)
T4E_4237Uncharacterized protein. (70 aa)
ShfSH2 domain-containing adapter protein F. (400 aa)
unc-93-2Putative potassium channel regulatory protein unc-93. (346 aa)
mus81-2Crossover junction endonuclease MUS81. (266 aa)
EME1Crossover junction endonuclease EME1. (455 aa)
Rad51dDNA repair protein RAD51-like protein 4. (272 aa)
MRE11ADouble-strand break repair protein MRE11A. (1123 aa)
T4E_10094Regulator of telomere elongation helicase 1-like protein. (1022 aa)
T4E_4003Regulator of telomere elongation helicase 1-like protein. (1041 aa)
CYP10Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (179 aa)
pold2DNA polymerase delta subunit 2. (475 aa)
tmc-2DNA repair and recombination protein RAD54B. (2003 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (861 aa)
PPP1R21BRCA1-A complex subunit BRE. (392 aa)
Ddx52Putative ATP-dependent RNA helicase DDX52. (559 aa)
Topbp1DNA topoisomerase 2-binding protein 1. (826 aa)
RAD54LDNA repair and recombination protein RAD54-like. (746 aa)
him-6Bloom syndrome-like protein. (264 aa)
T4E_3040Uncharacterized protein. (116 aa)
RAD51CDNA repair protein RAD51-like protein 3. (224 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (482 aa)
mus81Crossover junction endonuclease MUS81. (200 aa)
mus309Bloom syndrome-like protein. (345 aa)
unc-93Putative potassium channel regulatory protein unc-93. (252 aa)
Your Current Organism:
Trichinella pseudospiralis
NCBI taxonomy Id: 6337
Other names: T. pseudospiralis
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