STRINGSTRING
hppK hppK BAH98766.1 BAH98766.1 BAH98744.1 BAH98744.1 BAH98741.1 BAH98741.1 BAH98720.1 BAH98720.1 BAH98697.1 BAH98697.1 BAH98579.1 BAH98579.1 BAH98564.1 BAH98564.1 prs prs ispE ispE phoR phoR chvG chvG BAH98435.1 BAH98435.1 BAH98412.1 BAH98412.1 BAH98331.1 BAH98331.1 BAH98330.1 BAH98330.1 BAH98312.1 BAH98312.1 pfkB pfkB BAH98241.1 BAH98241.1 BAH98238.1 BAH98238.1 cmk cmk BAH98196.1 BAH98196.1 pgk pgk BAH98165.1 BAH98165.1 BAI00752.1 BAI00752.1 BAI00686.1 BAI00686.1 BAI00599.1 BAI00599.1 BAI00463.1 BAI00463.1 BAI00447.1 BAI00447.1 BAI00431.1 BAI00431.1 tal tal BAI00425.1 BAI00425.1 BAI00390.1 BAI00390.1 BAI00365.1 BAI00365.1 cobP cobP anmK anmK BAI00103.1 BAI00103.1 thrB thrB BAI00096.1 BAI00096.1 BAI00094.1 BAI00094.1 BAI00089.1 BAI00089.1 ndk ndk BAI00036.1 BAI00036.1 BAI00035.1 BAI00035.1 proB proB ntrB ntrB ntrY ntrY envZ envZ BAH99800.1 BAH99800.1 baf baf BAH99740.1 BAH99740.1 BAH99729.1 BAH99729.1 BAH99629.1 BAH99629.1 ackA ackA BAH99548.1 BAH99548.1 BAH99471.1 BAH99471.1 BAH99409.1 BAH99409.1 glpK glpK thiL thiL tpiA tpiA pdhA pdhA BAH99364.1 BAH99364.1 lpxK lpxK BAH99314.1 BAH99314.1 cysC cysC tmk tmk BAH99275.1 BAH99275.1 eno eno BAH99171.1 BAH99171.1 BAH99170.1 BAH99170.1 gpmI gpmI adk adk BAH99066.1 BAH99066.1 ppk ppk coaE coaE aroK aroK BAH98914.1 BAH98914.1 ribF ribF hldE hldE gmk gmk argB argB pyrH pyrH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hppK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase HppK. (170 aa)
BAH98766.1Pyruvate kinase; Belongs to the pyruvate kinase family. (486 aa)
BAH98744.1Pyruvate dehydrogenase E1 component alpha subunit. (331 aa)
BAH98741.1Hypothetical protein. (305 aa)
BAH98720.1Glycerate dehydrogenase; Hydroxypyruvate reductase. (419 aa)
BAH98697.1Aminoglycoside phospho transferase. (416 aa)
BAH98579.1N-acetylglucosamine kinase; BadF/BadG/BcrA/BcrD type. (328 aa)
BAH98564.1Phosphoglycerate mutase. (200 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (301 aa)
phoRTwo component sensor histidine kinase PhoR. (435 aa)
chvGTwo component sensor histidine kinase ChvG. (600 aa)
BAH98435.1Hypothetical protein. (305 aa)
BAH98412.1Fructose-bisphosphate aldolase. (304 aa)
BAH98331.1Protein kinase. (360 aa)
BAH98330.1Protein kinase. (352 aa)
BAH98312.1Two component hybrid sensor histidine kinase and regulator. (1160 aa)
pfkBSugar kinase PfkB; Fructokinase, carbohydrate kinase. (332 aa)
BAH98241.1Glycerate dehydrogenase; Hydroxypyruvate reductase. (431 aa)
BAH98238.1Two component hybrid sensor histidine kinase and regulator; PAS/PAC repeat. (747 aa)
cmkCytidylate kinase. (217 aa)
BAH98196.1Transketolase; Belongs to the transketolase family. (643 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (407 aa)
BAH98165.1Hypothetical protein; Belongs to the UPF0434 family. (61 aa)
BAI00752.1Adenosine 5'-monophosphoramidase; Histidine triad (HIT) protein. (124 aa)
BAI00686.1Phosphoglycerate/bisphosphoglycerate mutase. (231 aa)
BAI00599.1Hypothetical protein. (178 aa)
BAI00463.1Phosphoglycerate/bisphosphoglycerate mutase. (197 aa)
BAI00447.1Two component hybrid sensor histidine kinase and regulator. (1105 aa)
BAI00431.1Gluconokinase; Carbohydrate kinase, thermoresistant glucokinase. (194 aa)
talBifunctional protein [transaldolase and glucose-6-phosphate isomerase]; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. (951 aa)
BAI00425.1Transketolase; Belongs to the transketolase family. (700 aa)
BAI00390.1Hypothetical protein. (353 aa)
BAI00365.1Phosphoglycerate mutase; Alpha-ribazole-5'-phosphate phosphatase. (204 aa)
cobPAdenosylcobalamin biosynthesis bifunctional protein CobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (184 aa)
anmKHypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (381 aa)
BAI00103.1ABC transporter ATP-binding protein. (455 aa)
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (324 aa)
BAI00096.1ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (271 aa)
BAI00094.1Tetratricopeptide repeat family protein. (287 aa)
BAI00089.1Two component sensor histidine kinase. (310 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (160 aa)
BAI00036.1Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (274 aa)
BAI00035.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (891 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (375 aa)
ntrBTwo component sensor histidine kinase NtrB; Nitrogen regulation protein. (369 aa)
ntrYTwo component sensor histidine kinase NtrY; Nitrogen assimilation regulatory protein. (754 aa)
envZTwo component sensor histidine kinase EnvZ; Osmolarity sensor protein. (460 aa)
BAH99800.1Thiamin pyrophosphokinase; MutT/nudix hydrolase family. (290 aa)
bafTranscriptional activator Baf; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (269 aa)
BAH99740.1Diacylglycerol (DAG) kinase. (326 aa)
BAH99729.1Two component sensor histidine kinase. (450 aa)
BAH99629.1Fructokinase; ROK family protei, N-acetyl-D-glucosamine kinase. (297 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
BAH99548.1DNA helicase. (2008 aa)
BAH99471.1Phosphomethylpyrimidine kinase. (276 aa)
BAH99409.1Two component hybrid sensor histidine kinase and regulator; PAS/PAC repeats. (560 aa)
glpKGlycerol kinase (variant); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (329 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (336 aa)
BAH99364.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (451 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (331 aa)
BAH99314.13-deoxy-D-manno-octulosonic-acid transferase. (673 aa)
cysCSulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (626 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa)
BAH99275.1Aspartate kinase; Belongs to the aspartokinase family. (438 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
BAH99171.1Two component hybrid sensor histidine kinase and regulator; PAS/PAC repeats. (666 aa)
BAH99170.1Two component sensor histidine kinase; Chromosome variant locus=Gap14 no-insertion. (616 aa)
gpmIPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (222 aa)
BAH99066.1Two component sensor histidine kinase. (464 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (761 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (195 aa)
aroKShikimate kinase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (577 aa)
BAH98914.12-oxoglutarate dehydrogenase E1 component. (1004 aa)
ribFRiboflavin kinase RibF; Belongs to the ribF family. (315 aa)
hldEADP-heptose synthase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (477 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (217 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (305 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (258 aa)
Your Current Organism:
Acetobacter pasteurianus
NCBI taxonomy Id: 634452
Other names: A. pasteurianus IFO 3283-01, Acetobacter pasteurianus IFO 3283-01
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