Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.

Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.

Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.

Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.

AAA ATPase; Related to the helicase subunit of the Holliday junction resolvase.

Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.

DNA helicase C2; ATP-dependent.

DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

DNA helicase C2; ATP-dependent.

DNA helicase II UvrD/Rep; ATP-dependent.

Cell division AAA ATPase FtsH.

Heat shock protein HtpG/Hsp90; Molecular chaperone. Has ATPase activity.

Iron-sulfur cluster assembly/repair protein ApbC; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.

Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.

GTP-binding protein TypA/BipA.

Translation elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G [...]

GTP-binding protein TypA/BipA.

Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.

GTP-binding protein TypA/BipA.

GTP-binding protein ObgE/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

GTP-binding protein TypA/BipA.

Translation peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.

GTP-binding protein TypA/BipA.

GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.

Clp protease ATP-binding subunit ClpA; ATP-dependent; Belongs to the ClpA/ClpB family.

Endopeptidase ATP-dependent hsl ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.

Clp protease ATP-binding subunit ClpA; ATP-dependent; Belongs to the ClpA/ClpB family.

Heat shock protein HtpG/Hsp90; Molecular chaperone. Has ATPase activity.

Clp protease ATP-binding subunit ClpA; ATP-dependent; Belongs to the ClpA/ClpB family.

Lon protease ATP-dependent Lon; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.

Clp protease ATP-binding subunit ClpA; ATP-dependent; Belongs to the ClpA/ClpB family.

Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

Clp protease ATP-binding subunit ClpA; ATP-dependent, IMP dehydrogenase/GMP reductase.

Endopeptidase ATP-dependent hsl ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.

Clp protease ATP-binding subunit ClpA; ATP-dependent, IMP dehydrogenase/GMP reductase.

Heat shock protein HtpG/Hsp90; Molecular chaperone. Has ATPase activity.

Clp protease ATP-binding subunit ClpA; ATP-dependent, IMP dehydrogenase/GMP reductase.

Translation initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

Clp protease ATP-binding subunit ClpA; ATP-dependent, IMP dehydrogenase/GMP reductase.

Lon protease ATP-dependent Lon; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.