STRINGSTRING
murC murC murD murD murF murF murE murE BAH99864.1 BAH99864.1 BAH99855.1 BAH99855.1 gshB gshB BAH99762.1 BAH99762.1 argG argG BAH99546.1 BAH99546.1 BAH99433.1 BAH99433.1 pyrG pyrG purC purC purS purS purQ purQ purL purL exsB/queC exsB/queC bioD bioD purK purK gatB gatB carA carA carB carB purM purM BAH98780.1 BAH98780.1 purA purA BAH98427.1 BAH98427.1 purD purD BAH98408.1 BAH98408.1 nadE nadE tilS tilS folC folC gatB-2 gatB-2 gatA gatA gatC gatC BAI00627.1 BAI00627.1 guaA guaA cbiA cbiA BAI00169.1 BAI00169.1 panC panC BAI00041.1 BAI00041.1 ddl ddl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (477 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (471 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (461 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (489 aa)
BAH99864.1Asparagine synthetase; Glutamine-hydrolase. (586 aa)
BAH99855.1Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (469 aa)
gshBGlutathione synthetase; Belongs to the prokaryotic GSH synthase family. (331 aa)
BAH99762.1biotin--acetyl-CoA-carboxylase ligase. (247 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (413 aa)
BAH99546.1Amidase; Urea amidolyase, allophanate hydrolase. (611 aa)
BAH99433.1Amidase; Amidotransferase A subunit for Asp-tRNA(Asn)/Glu-tRNA(Gln). (451 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa)
purCPhosphoribosyl amidoimidazole succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (255 aa)
purSPhosphoribosyl formylglycinamidine synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa)
purQPhosphoribosyl formylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (233 aa)
purLPhosphoribosyl formylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (734 aa)
exsB/queCQueuosine biosynthesis protein QueC/ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (246 aa)
bioDBiotin synthesis protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (465 aa)
purKPhosphoribosyl aminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (389 aa)
gatBAmidotransferase GatB/YqeY subunit for mischarged Glu-tRNA(Gln); Indirect pathway of Gln-tRNA formation GatCAB subunit. (151 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (466 aa)
carBCarbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1084 aa)
purMPhosphoribosyl formylglycinamidine cyclo-ligase. (360 aa)
BAH98780.1Glutamine synthetase. (481 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
BAH98427.1lysyl-tRNA synthetase. (341 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (427 aa)
BAH98408.15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (195 aa)
nadENAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (677 aa)
tilSIle-tRNA lysidine synthase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (435 aa)
folCBifunctional protein FolC; Folylpolyglutamate synthase;dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (445 aa)
gatB-2glutamyl-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (484 aa)
gatAAmidotransferase A subunit for Asp-tRNA(Asn)/Glu-tRNA(Gln); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (495 aa)
gatCglutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa)
BAI00627.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
guaAGlutamine amidotransferase; Catalyzes the synthesis of GMP from XMP. (533 aa)
cbiACobyrinic acid a,c-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (453 aa)
BAI00169.1Hypothetical protein. (492 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (343 aa)
BAI00041.1Nicotinic acid phosphoribosyltransferase. (415 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (312 aa)
Your Current Organism:
Acetobacter pasteurianus
NCBI taxonomy Id: 634452
Other names: A. pasteurianus IFO 3283-01, Acetobacter pasteurianus IFO 3283-01
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