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gpmB gpmB cbiT cbiT cbiL cbiL cbiF cbiF cbiG cbiG cobJ1 cobJ1 cobJ2 cobJ2 cbiC cbiC cbiJ cbiJ hemC hemC cysG2 cysG2 hemD hemD cobT cobT cbiA2 cbiA2 cadT cadT hemA2 hemA2 hemX hemX HAH_2439 HAH_2439 cobD cobD cobS cobS ispD ispD hisC2 hisC2 HAH_2444 HAH_2444 cobO cobO cobQ cobQ hemB hemB hemL hemL
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpmBPhosphoglycerate mutase. (209 aa)
cbiTprecorrin-8W decarboxylase. (225 aa)
cbiLCobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. (265 aa)
cbiFCobalamin biosynthesis precorrin-3 methylase. (300 aa)
cbiGCobalamin biosynthesis protein CbiG. (323 aa)
cobJ1precorrin-3B C17-methyltransferase. (308 aa)
cobJ2precorrin-3B C17-methyltransferase. (359 aa)
cbiCprecorrin-8X methylmutase. (243 aa)
cbiJcobalt-precorrin-6Y C(5)-methyltransferase. (253 aa)
hemCPorphobilinogen deaminase. (389 aa)
cysG2uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (253 aa)
hemDuroporphyrinogen-III synthase. (262 aa)
cobTNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Belongs to the UPF0284 family. (346 aa)
cbiA2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (441 aa)
cadTATP/cobalamin adenosyltransferase. (178 aa)
hemA2glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (448 aa)
hemXuroporphyrin-III C-methyltransferase. (211 aa)
HAH_2439Haloacid dehalogenase domain protein hydrolase. (212 aa)
cobDPutative CobD/Cbib protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (306 aa)
cobSPutative cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (267 aa)
ispD4-diphosphocytidyl-2C-methyl-D-erythritol synthase. (179 aa)
hisC2Histidinol-phosphate aminotransferase. (352 aa)
HAH_2444Cobalamine operon protein. (238 aa)
cobOCobalamin adenosyltransferase. (216 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (492 aa)
hemBDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
hemLGlutamate-1-semialdehyde 21-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (445 aa)
Your Current Organism:
Haloarcula hispanica
NCBI taxonomy Id: 634497
Other names: H. hispanica ATCC 33960, Haloarcula hispanica ATCC 33960, Haloarcula hispanica DSM 4426, Haloarcula hispanica JCM 8911, Haloarcula hispanica str. ATCC 33960, Haloarcula hispanica strain ATCC 33960
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