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EbC_00030 EbC_00030 viaA viaA ravA ravA cpxP cpxP yiiQ yiiQ yiiR yiiR zapB zapB wecA wecA wzzE wzzE wecB wecB wecC wecC wecD wecD rffA rffA wzxE wzxE wecF wecF wzyE wzyE wecG wecG psiE psiE yjbO yjbO EbC_03610 EbC_03610 EbC_04310 EbC_04310 EbC_04670 EbC_04670 EbC_04710 EbC_04710 ytfK ytfK EbC_05010 EbC_05010 smp smp slt slt sgrR sgrR secM secM yacL yacL yacC yacC EbC_08060 EbC_08060 rof rof EbC_08830 EbC_08830 crl crl EbC_08850 EbC_08850 ybaE ybaE ymoA ymoA ymoB ymoB EbC_12820 EbC_12820 ybgE ybgE ompX ompX ycaD ycaD EbC_15110 EbC_15110 ompF ompF ycbW ycbW tfoX tfoX helD helD EbC_15740 EbC_15740 mdoC mdoC opgG opgG mdoH mdoH EbC_16100 EbC_16100 solA solA bssS bssS EbC_16260 EbC_16260 EbC_16640 EbC_16640 EbC_16650 EbC_16650 lpoB lpoB ycfP ycfP phoE phoE EbC_18220 EbC_18220 ychP ychP phoE-2 phoE-2 phoE-3 phoE-3 osmE osmE yniB yniB ydiY ydiY lpp lpp EbC_19310 EbC_19310 cnu cnu EbC_19720 EbC_19720 tus tus hns hns ycfR ycfR ycfR-2 ycfR-2 EbC_19920 EbC_19920 ynfB ynfB ydgD ydgD asr asr EbC_20020 EbC_20020 EbC_20840 EbC_20840 EbC_22920 EbC_22920 EbC_23560 EbC_23560 EbC_23690 EbC_23690 EbC_23930 EbC_23930 hns-2 hns-2 EbC_24460 EbC_24460 EbC_24610 EbC_24610 EbC_25240 EbC_25240 flhE flhE EbC_26170 EbC_26170 EbC_26180 EbC_26180 asmA asmA EbC_30150 EbC_30150 EbC_30850 EbC_30850 EbC_31290 EbC_31290 EbC_31400 EbC_31400 EbC_32640 EbC_32640 EbC_33010 EbC_33010 sseB sseB csiE csiE EbC_34380 EbC_34380 EbC_35680 EbC_35680 EbC_36760 EbC_36760 pagC pagC tolC tolC ampH ampH EbC_39610 EbC_39610 EbC_40590 EbC_40590 EbC_40600 EbC_40600 EbC_40610 EbC_40610 EbC_40620 EbC_40620 aaeB aaeB aaeA aaeA aaeX aaeX EbC_41720 EbC_41720 tsgA tsgA damX damX IgaA IgaA yhhK yhhK EbC_42560 EbC_42560 uspB uspB uspA uspA yiaF yiaF EbC_45240 EbC_45240 EbC_45250 EbC_45250 EbC_45530 EbC_45530 EbC_45540 EbC_45540
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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EbC_00030Conserved uncharacterized protein; silverDB:661Eb00003. (714 aa)
viaAProtein ViaA, VWA-domain protein interacting with AAA ATPase; silverDB:661Eb00004. (486 aa)
ravARegulatory ATPase variant A; silverDB:661Eb00006. (498 aa)
cpxPPeriplasmic repressor of cpx regulon by interaction with CpxA; silverDB:661Eb00111. (169 aa)
yiiQConserved uncharacterized protein YiiQ; silverDB:661Eb00177. (197 aa)
yiiRConserved uncharacterized protein YiiR; silverDB:661Eb00178. (147 aa)
zapBConserved uncharacterized protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa)
wecAUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (359 aa)
wzzELipopolysaccharide biosynthesis protein WzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family. (341 aa)
wecBUDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
wecCUDP-N-acetyl-D-mannosamine dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
wecDLipopolysaccharide biosynthesis protein; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. (239 aa)
rffATDP-4-oxo-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
wzxELipopolysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. (416 aa)
wecF4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. (356 aa)
wzyEPutative ECA polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family. (446 aa)
wecGProbable UDP-N-acetyl-D-mannosaminuronic acid transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. (243 aa)
psiEPhosphate-starvation-inducible E, protein PsiE; silverDB:661Eb00393. (132 aa)
yjbOSimilar to conserved hypothetical protein YjbO; silverDB:661Eb00406. (76 aa)
EbC_03610Conserved uncharacterized protein; silverDB:661Eb00473. (181 aa)
EbC_04310Putative lipoprotein; silverDB:661Eb00570. (117 aa)
EbC_04670Conserved uncharacterized protein; silverDB:661Eb00620. (184 aa)
EbC_04710Conserved uncharacterized protein; silverDB:661Eb00626. (185 aa)
ytfKConserved uncharacterized protein YtfK; silverDB:661Eb00627. (68 aa)
EbC_05010Conserved uncharacterized protein; silverDB:661Eb00666; Belongs to the UPF0149 family. (201 aa)
smpMembrane protein; silverDB:661Eb00825. (221 aa)
sltSoluble lytic murein transglycosylase; silverDB:661Eb00886. (621 aa)
sgrRSugar transport-related sRNA regulator SgrR; silverDB:661Eb00963. (553 aa)
secMSecretion monitor family protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family. (166 aa)
yacLConserved uncharacterized protein, putative cytoplasmic protein; silverDB:661Eb01039; Belongs to the UPF0231 family. (120 aa)
yacCConserved uncharacterized protein YacC; silverDB:661Eb01055. (115 aa)
EbC_08060Conserved uncharacterized protein; silverDB:661Eb01094; Belongs to the UPF0325 family. (130 aa)
rofRho-binding antiterminator protein; silverDB:661Eb01127. (87 aa)
EbC_08830Putative esterase; silverDB:661Eb01198; Belongs to the UPF0255 family. (416 aa)
crlCurlin genes transcriptional activatory protein; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (133 aa)
EbC_08850Outer membrane protein C2; silverDB:661Eb01200; Belongs to the Gram-negative porin family. (371 aa)
ybaEABC superfamily transporter, permease; silverDB:661Eb01375. (566 aa)
ymoAPutative YmoA, negative regulator of invasin expression; silverDB:cbdbB8. (72 aa)
ymoBPutative YmoB (Similar to YbaJ) associated to the expression of invasin; silverDB:cbdbB9. (126 aa)
EbC_12820Putative membrane protein; silverDB:661Eb01731. (68 aa)
ybgEPutative membrane protein YbgE; silverDB:661Eb01761. (97 aa)
ompXVirulence-related outer membrane protein X; silverDB:661Eb01929. (171 aa)
ycaDMFS-type transporter protein YcaD; silverDB:661Eb02009. (383 aa)
EbC_15110Conserved uncharacterized protein; silverDB:661Eb02029. (297 aa)
ompFOuter membrane protein F; silverDB:661Eb02042; Belongs to the Gram-negative porin family. (368 aa)
ycbWConserved uncharacterized protein YcbW; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (180 aa)
tfoXRegulator of competence-specific genes; silverDB:661Eb02067. (209 aa)
helDHelicase IV; silverDB:661Eb02070. (684 aa)
EbC_15740Conserved uncharacterized protein; silverDB:661Eb02102. (74 aa)
mdoCGlucans biosynthesis protein C; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (383 aa)
opgGPeriplasmatic glucans biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (518 aa)
mdoHGlucans biosynthesis glucosyltransferase H; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (856 aa)
EbC_16100Conserved uncharacterized protein; silverDB:661Eb02157. (80 aa)
solAN-methyl-L-tryptophan oxidase; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily. (371 aa)
bssSBiofilm regulator; silverDB:661Eb02174. (84 aa)
EbC_16260Conserved uncharacterized protein; silverDB:661Eb02179. (188 aa)
EbC_16640HIT family protein; silverDB:661Eb02231. (116 aa)
EbC_16650Conserved uncharacterized protein; silverDB:661Eb02233. (122 aa)
lpoBPutative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. (198 aa)
ycfPConserved uncharcterized protein YcfP; silverDB:661Eb02237; Belongs to the UPF0227 family. (180 aa)
phoEOuter membrane pore protein E; silverDB:661Eb02336. (356 aa)
EbC_18220Putative membrane protein; silverDB:661Eb02459. (94 aa)
ychPPutative invasin; silverDB:661Eb02505. (476 aa)
phoE-2Outer membrane pore protein E, porin formation; silverDB:661Eb02507. (354 aa)
phoE-3Outer membrane pore protein E, porin formation; silverDB:661Eb02509. (355 aa)
osmEOsmotically-inducible lipoprotein E (Activator of ntr-like gene); silverDB:661Eb02525. (111 aa)
yniBConserved uncharacterized protein YniB; silverDB:661Eb02533. (179 aa)
ydiYConserved uncharacterized protein YdiY; silverDB:661Eb02538. (251 aa)
lppMajor outer membrane lipoprotein; silverDB:661Eb02574. (78 aa)
EbC_19310Putative lipoprotein; silverDB:661Eb02604. (103 aa)
cnuOriC-binding nucleoid-associated protein; silverDB:661Eb02633. (71 aa)
EbC_19720Conserved uncharacterized protein; silverDB:661Eb02662. (500 aa)
tusDNA replication terminus site-binding protein (Ter protein); silverDB:661Eb02667. (309 aa)
hnsHeat-stable nucleoid-structuring protein; silverDB:661Eb02668; Belongs to the histone-like protein H-NS family. (133 aa)
ycfRConserved uncharacterized protein YcfR; silverDB:661Eb02671. (85 aa)
ycfR-2Outer membrane protein YcfR; silverDB:661Eb02672. (84 aa)
EbC_19920Conserved uncharacterized protein; silverDB:661Eb02687. (98 aa)
ynfBConserved uncharacterized protein YnfB; silverDB:661Eb02688; Belongs to the UPF0482 family. (116 aa)
ydgDPutative protease YdgD; silverDB:661Eb02690; Belongs to the peptidase S1B family. (271 aa)
asrUncharacterized protein; Required for growth and/or survival at acidic conditions. (174 aa)
EbC_20020Conserved uncharacterized protein; silverDB:661Eb02698. (316 aa)
EbC_20840Conserved uncharacterized protein; silverDB:661Eb02803. (130 aa)
EbC_22920Murein peptide amidase A; silverDB:661Eb03079. (235 aa)
EbC_23560Osmotically inducible lipoprotein B; silverDB:661Eb03164. (72 aa)
EbC_23690Uncharacterized protein; silverDB:661Eb03180. (81 aa)
EbC_23930dsDNA-mimic protein; silverDB:661Eb03209; Belongs to the UPF0263 family. (111 aa)
hns-2Histone-like nucleoid-structuring protein (H-NS); silverDB:661Eb03220; Belongs to the histone-like protein H-NS family. (135 aa)
EbC_24460Conserved uncharacterized protein; silverDB:661Eb03273. (198 aa)
EbC_24610Conserved uncharacterized protein; silverDB:661Eb03291. (152 aa)
EbC_25240Conserved uncharacterized protein; silverDB:661Eb03365. (188 aa)
flhEFlagellar protein; silverDB:661Eb03370. (129 aa)
EbC_26170Chaperone, TorD family; silverDB:661Eb03482. (184 aa)
EbC_26180Putative hydrolase; silverDB:661Eb03484; Belongs to the PHP family. (245 aa)
asmAAsmA suppressor of OmpF assembly mutants; silverDB:661Eb03898. (614 aa)
EbC_30150Conserved uncharacterized protein; silverDB:661Eb03990. (113 aa)
EbC_30850Conserved uncharacterized protein; silverDB:661Eb04079; Belongs to the UPF0304 family. (164 aa)
EbC_31290Conserved uncharacterized protein; silverDB:661Eb04137. (93 aa)
EbC_31400Conserved uncharacterized protein; silverDB:661Eb04150. (98 aa)
EbC_32640Putative negative regulator; silverDB:661Eb04283. (119 aa)
EbC_33010Conserved uncharacterized protein; silverDB:661Eb04330. (205 aa)
sseBEnhanced serine sensitivity; silverDB:661Eb04431. (259 aa)
csiEStationary phase-inducible protein; silverDB:661Eb04439. (422 aa)
EbC_34380Conserved uncharacterized protein; silverDB:661Eb04491. (111 aa)
EbC_35680Conserved uncharacterized protein; silverDB:661Eb04663. (74 aa)
EbC_36760Conserved uncharacterized protein; silverDB:661Eb04817. (237 aa)
pagCVirulence membrane protein; silverDB:661Eb04867. (187 aa)
tolCOuter membrane efflux protein; silverDB:661Eb05052. (492 aa)
ampHPenicillin-binding protein; silverDB:661Eb05098. (397 aa)
EbC_39610Conserved uncharacterized protein; silverDB:661Eb05183. (170 aa)
EbC_40590Conserved uncharacterized protein; silverDB:661Eb05319. (87 aa)
EbC_40600Conserved uncharacterized protein; silverDB:661Eb05320. (89 aa)
EbC_40610Conserved uncharacterized protein; silverDB:661Eb05321. (87 aa)
EbC_40620Succinate semialdehyde dehydrogenase; silverDB:661Eb05322; Belongs to the aldehyde dehydrogenase family. (484 aa)
aaeBP-hydroxybenzoic acid efflux pump subunit B (PHBA efflux pump protein B); Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. (652 aa)
aaeAP-hydroxybenzoic acid efflux pump subunit A (PHBA efflux pump protein A); Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (310 aa)
aaeXConserved hypothetical protein; silverDB:661Eb05325. (67 aa)
EbC_41720Putative membrane protein; silverDB:661Eb05456. (692 aa)
tsgAMajor facilitator family transporter; silverDB:661Eb05465. (394 aa)
damXConserved uncharacterized protein; Non-essential cell division protein. (342 aa)
IgaAIntracellular growth attenuator protein; silverDB:661Eb05490. (712 aa)
yhhKAcetyltransferase; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family. (131 aa)
EbC_42560Putative membrane protein; silverDB:661Eb05574. (208 aa)
uspBUniversal stress protein B; silverDB:661Eb05639. (111 aa)
uspAUniversal stress protein A; silverDB:661Eb05640. (145 aa)
yiaFConserved uncharacterized protein yiaF; silverDB:661Eb05933. (238 aa)
EbC_45240Mannitol repressor protein; silverDB:661Eb05937. (182 aa)
EbC_45250Conserved uncharacterized protein; silverDB:661Eb05939. (120 aa)
EbC_45530Putative lipoprotein; silverDB:661Eb05980. (122 aa)
EbC_45540Conserved uncharacterized protein; silverDB:661Eb05981. (423 aa)
Your Current Organism:
Erwinia billingiae
NCBI taxonomy Id: 634500
Other names: E. billingiae Eb661, Erwinia billingiae Eb661, Erwinia billingiae str. Eb661, Erwinia billingiae strain Eb661
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