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kdtA kdtA SVI_0180 SVI_0180 SVI_0268 SVI_0268 SVI_0408 SVI_0408 mgtE mgtE ptsO ptsO SVI_0411 SVI_0411 ptsN ptsN yfiA-1 yfiA-1 SVI_0415 SVI_0415 lptA lptA lptC lptC SVI_0418 SVI_0418 SVI_0419 SVI_0419 SVI_0420 SVI_0420 SVI_0421 SVI_0421 SVI_0422 SVI_0422 SVI_0423 SVI_0423 SVI_0424 SVI_0424 SVI_0425 SVI_0425 SVI_0426 SVI_0426 SVI_0427 SVI_0427 degS degS SVI_0430 SVI_0430 SVI_0557 SVI_0557 htrB htrB kdsB-1 kdsB-1 imp imp SVI_0839 SVI_0839 SVI_0840 SVI_0840 SVI_0873 SVI_0873 SVI_0874 SVI_0874 ptsP ptsP SVI_0988 SVI_0988 SVI_1054 SVI_1054 bamA bamA ompH ompH lpxD lpxD fabZ fabZ lpxA lpxA lpxB lpxB SVI_1262 SVI_1262 smpA smpA SVI_1377 SVI_1377 bamB bamB SVI_1728 SVI_1728 SVI_1785 SVI_1785 SVI_1786 SVI_1786 tolQ tolQ tolR tolR tolA tolA tolB tolB pal pal cpoB cpoB SVI_1793 SVI_1793 nlpB nlpB kdsB-2 kdsB-2 crr crr ptsI ptsI ptsH ptsH SVI_2277 SVI_2277 lpxM lpxM SVI_2564 SVI_2564 lpxK lpxK SVI_2935 SVI_2935 lpxH lpxH kdsA kdsA lptE lptE bamD bamD azu azu SVI_3503 SVI_3503 SVI_3890 SVI_3890 SVI_3958 SVI_3958 lpxC lpxC
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdtA3-deoxy-D-manno-octulosonic-acid (KDO) transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (422 aa)
SVI_0180Hypothetical protein. (104 aa)
SVI_0268Patatin-like phospholipase family. (740 aa)
SVI_0408OmpA family protein. (220 aa)
mgtEMagnesium transporter; Acts as a magnesium transporter. (453 aa)
ptsOPhosphocarrier protein NPr; Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr. Phospho-NPr then transfers it to EIIA-Ntr. Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins; Belongs to the HPr family. (91 aa)
SVI_0411Conserved hypothetical protein; Displays ATPase and GTPase activities. (282 aa)
ptsNNitrogen regulatory IIA protein. (147 aa)
yfiA-1Ribosomal subunit interface protein. (95 aa)
SVI_0415ABC transporter, ATP-binding protein. (240 aa)
lptAConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (217 aa)
lptCConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (185 aa)
SVI_0418Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (185 aa)
SVI_0419Carbohydrate isomerase, KpsF/GutQ family. (325 aa)
SVI_0420K+-dependent Na+/Ca+ exchanger related-protein. (319 aa)
SVI_0421Hypothetical protein. (45 aa)
SVI_0422ABC transporter, ATP-binding protein, putative. (272 aa)
SVI_0423Conserved hypothetical protein. (258 aa)
SVI_0424Mce-related protein. (154 aa)
SVI_0425Toluene tolerance protein, putative. (218 aa)
SVI_0426SpoIIAA family protein. (100 aa)
SVI_0427BolA/YrbA family protein; Belongs to the BolA/IbaG family. (95 aa)
degSProtease DegS. (360 aa)
SVI_0430Serine protease, HtrA/DegQ/DegS family; Belongs to the peptidase S1C family. (450 aa)
SVI_0557OmpA family protein. (277 aa)
htrBLipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (308 aa)
kdsB-13-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family. (270 aa)
impOrganic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (752 aa)
SVI_0839Conserved hypothetical protein. (370 aa)
SVI_0840Conserved hypothetical protein. (352 aa)
SVI_0873Hypothetical protein. (394 aa)
SVI_0874Hypothetical protein. (1378 aa)
ptsPPhosphoenolpyruvate-protein phosphotransferase PtsP; Belongs to the PEP-utilizing enzyme family. (741 aa)
SVI_0988OmpA family protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (361 aa)
SVI_1054OmpA family protein. (210 aa)
bamASurface antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (827 aa)
ompHOuter membrane protein OmpH; Belongs to the skp family. (167 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (341 aa)
fabZ(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (152 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (255 aa)
lpxBLipid A disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (381 aa)
SVI_1262Lipoprotein, putative. (128 aa)
smpASmall protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (185 aa)
SVI_1377Conserved hypothetical protein. (206 aa)
bamBPQQ enzyme repeat domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (395 aa)
SVI_1728OmpA family protein. (197 aa)
SVI_1785Prolyl endopeptidase. (710 aa)
SVI_1786Thioesterase superfamily. (132 aa)
tolQMotA/TolQ/ExbB proton channel family protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (229 aa)
tolRtolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (144 aa)
tolAtolA protein. (319 aa)
tolBtolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (442 aa)
palPeptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (178 aa)
cpoBConserved hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (246 aa)
SVI_1793Hypothetical protein. (40 aa)
nlpBLipoprotein-34 NlpB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (373 aa)
kdsB-23-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family. (245 aa)
crrPTS system, glucose-specific IIA component. (169 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (571 aa)
ptsHPhosphocarrier protein HPr. (85 aa)
SVI_2277Hypothetical protein. (703 aa)
lpxMLipid A biosynthesis acyltransferase, putative; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (311 aa)
SVI_2564Conserved hypothetical protein. (301 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (340 aa)
SVI_2935OmpA family protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (335 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (244 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (282 aa)
lptERare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (164 aa)
bamDConserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (253 aa)
azuAzurin; Transfers electrons from cytochrome c551 to cytochrome oxidase. (162 aa)
SVI_3503Hypothetical protein. (182 aa)
SVI_3890OmpA family protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (334 aa)
SVI_3958Conserved hypothetical protein. (202 aa)
lpxCUDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (306 aa)
Your Current Organism:
Shewanella violacea
NCBI taxonomy Id: 637905
Other names: S. violacea DSS12, Shewanella violacea DSS12, Shewanella violacea JCM 10179, Shewanella violacea str. DSS12, Shewanella violacea strain DSS12
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