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| | SVI_0017 | Helicase. (1056 aa) |
| | SVI_0024 | ATP-dependent helicase HrpB, putative. (860 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (806 aa) |
| | SVI_0208 | Hypothetical protein. (233 aa) |
| | SVI_1957 | ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (448 aa) |
| | SVI_1866 | Conserved hypothetical protein. (589 aa) |
| | SVI_1862 | ABC transporter, ATP-binding protein. (639 aa) |
| | clpA | ATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (752 aa) |
| | SVI_1797 | Helicase. (580 aa) |
| | SVI_1741 | Phosphonate ABC transporter, permease protein, putative. (516 aa) |
| | SVI_1740 | ABC transporter, ATP-binding protein. (229 aa) |
| | smc | SMC family protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1136 aa) |
| | hscA | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa) |
| | secF-1 | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa) |
| | secD-1 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (616 aa) |
| | SVI_1546 | ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (431 aa) |
| | SVI_1543 | ABC transporter, ATP-binding/permease protein, putative. (609 aa) |
| | fliI | Flagellum-specific ATP synthase FliI. (446 aa) |
| | SVI_1344 | ATPase, putative. (509 aa) |
| | SVI_1101 | Hypothetical protein. (284 aa) |
| | SVI_0944 | Toxin secretion ATP-binding protein. (769 aa) |
| | SVI_0848 | ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (435 aa) |
| | SVI_0780 | iron(III) ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (342 aa) |
| | SVI_0770 | ABC transporter, ATP-binding protein. (589 aa) |
| | SVI_0741 | SEC-C motif domain protein. (110 aa) |
| | srmB | ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (408 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (531 aa) |
| | rbsA | Ribose ABC transporter, ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (494 aa) |
| | kpsT | Polysialic acid transport ATP-binding protein KpsT. (221 aa) |
| | SVI_0556 | AFG1-like ATPase superfamily. (380 aa) |
| | cydC | ABC transporter, ATP-binding protein CydC. (597 aa) |
| | cydD | ABC transporter, ATP-binding protein CydD. (611 aa) |
| | rhlE | ATP-dependent RNA helicase, DEAD box family; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (478 aa) |
| | dbpA | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. (469 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (619 aa) |
| | parC | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (757 aa) |
| | parE | DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (628 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (470 aa) |
| | zapE | AFG1-like ATPase superfamily; Reduces the stability of FtsZ polymers in the presence of ATP. (368 aa) |
| | groEL | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (546 aa) |
| | groES | Chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (96 aa) |
| | hepA | RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (731 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (458 aa) |
| | SVI_4295 | Transporter, putative. (387 aa) |
| | SVI_4241 | Molybdenum ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (368 aa) |
| | ccmA | Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (215 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (691 aa) |
| | recQ | ATP-dependent DNA helicase RecQ. (610 aa) |
| | secA | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (905 aa) |
| | uvrD | DNA helicase II. (721 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (670 aa) |
| | hslU | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (441 aa) |
| | rtxB | Toxin secretion ATP-binding protein. (724 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (422 aa) |
| | rhlB | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (438 aa) |
| | SVI_3818 | Toxin secretion ATP-binding protein. (706 aa) |
| | deaD | ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (617 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (945 aa) |
| | hrpB | ATP-dependent helicase HrpB. (868 aa) |
| | SVI_3604 | Conserved hypothetical protein. (1237 aa) |
| | SVI_3555 | ABC transporter, ATP-binding/permease protein, putative. (629 aa) |
| | SVI_3472 | TonB-dependent receptor. (667 aa) |
| | clpB | clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa) |
| | engD | GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | SVI_3379 | Toxin secretion ABC transporter protein, HlyB family. (746 aa) |
| | dnaK | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (640 aa) |
| | secD-2 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa) |
| | secF-2 | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa) |
| | ftsH | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (654 aa) |
| | secG | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (111 aa) |
| | radA | DNA repair protein RadA. (457 aa) |
| | SVI_3254 | ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (427 aa) |
| | SVI_3226 | ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (430 aa) |
| | SVI_3202 | ABC transporter, ATP-binding protein. (555 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (855 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa) |
| | SVI_3156 | SEC-C motif domain protein. (111 aa) |
| | copA | Copper-transporting P-type ATPase. (784 aa) |
| | SVI_3092 | Hypothetical protein. (55 aa) |
| | SVI_3091 | Hypothetical protein. (55 aa) |
| | SVI_3090 | Hypothetical protein. (55 aa) |
| | pstB | Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (272 aa) |
| | clpP | ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (203 aa) |
| | clpX | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (418 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (785 aa) |
| | dinG | ATP-dependent helicase DinG; DNA-dependent ATPase and 5'-3' DNA helicase. (701 aa) |
| | SVI_2966 | Conserved hypothetical protein. (260 aa) |
| | SVI_2937 | Hypothetical protein. (101 aa) |
| | SVI_2936 | ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family. (352 aa) |
| | SVI_2908 | MoxR-related protein. (318 aa) |
| | SVI_2902 | Conserved hypothetical protein. (202 aa) |
| | htpG | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. (638 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1157 aa) |
| | msbA | lipidA export ATP-binding/permease protein msbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (607 aa) |
| | SVI_2584 | Conserved hypothetical protein. (128 aa) |
| | SVI_2583 | Conserved hypothetical protein. (355 aa) |
| | SVI_2578 | ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (316 aa) |
| | SVI_2577 | Hypothetical protein. (87 aa) |
| | SVI_2481 | ATP-dependent helicase, DinG family. (648 aa) |
| | minD | Septum site-determining protein MinD. (269 aa) |
| | hrpA | ATP-dependent helicase HrpA. (1299 aa) |
| | recD | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (703 aa) |
| | recB | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1230 aa) |
| | recC | Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (1197 aa) |
| | SVI_2404 | MoxR-related protein. (303 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (339 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (671 aa) |
| | SVI_2294 | ATPase, AAA family. (443 aa) |
| | SVI_2234 | ATPase, FliI/YscN family. (441 aa) |
| | SVI_2223 | ATP-dependent protease, putative. (804 aa) |
| | SVI_2190 | Conserved hypothetical protein. (222 aa) |
| | SVI_2166 | Cation transport ATPase, E1-E2 family. (795 aa) |
| | SVI_2107 | Hypothetical protein. (671 aa) |
| | SVI_2097 | Hypothetical protein. (531 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (905 aa) |
| | SVI_2052 | ATP-dependent DNA helicase, RecQ family. (654 aa) |
| | SVI_2008 | Hypothetical protein. (466 aa) |
| | SVI_1985 | Helicase, Snf2 family. (694 aa) |
| | SVI_1961 | Hypothetical protein. (1331 aa) |
