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| | oxaA | Inner membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (544 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (743 aa) |
| | tolC | Outer membrane protein TolC. (447 aa) |
| | SVI_0944 | Toxin secretion ATP-binding protein. (769 aa) |
| | SVI_0945 | HlyD family secretion protein. (469 aa) |
| | ffh | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] (457 aa) |
| | yajC | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa) |
| | secD-1 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (616 aa) |
| | secF-1 | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa) |
| | SVI_2227 | Type III secretion system EscU protein. (349 aa) |
| | SVI_2228 | Type III secretion system apparatus protein, SpaR/YscT family. (229 aa) |
| | SVI_2229 | Type III secretion system EscS protein. (102 aa) |
| | SVI_2230 | Type III secretion system EscR protein. (216 aa) |
| | SVI_2231 | Hypothetical protein. (292 aa) |
| | SVI_2234 | ATPase, FliI/YscN family. (441 aa) |
| | SVI_2235 | Type III secretion system apparatus protein, HrcV family. (685 aa) |
| | SVI_2241 | Type III secretion system apparatus lipoprotein. (243 aa) |
| | SVI_2244 | Type III secretion system apparatus protein, putative. (71 aa) |
| | SVI_2260 | Type III secretion system EscC protein, putative. (491 aa) |
| | secG | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (111 aa) |
| | secF-2 | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (315 aa) |
| | secD-2 | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (604 aa) |
| | SVI_3378 | HlyD family secretion protein. (473 aa) |
| | SVI_3379 | Toxin secretion ABC transporter protein, HlyB family. (746 aa) |
| | tatA | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (79 aa) |
| | tatB | Sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (135 aa) |
| | tatC | Sec-independent periplasmic protein translocation protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (249 aa) |
| | secA | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (905 aa) |
| | secY | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (446 aa) |
| | secE | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (123 aa) |
| | gspM | General secretion pathway protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (158 aa) |
| | gspL | General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (397 aa) |
| | gspK | General secretion pathway protein K. (333 aa) |
| | gspJ | General secretion pathway protein J. (257 aa) |
| | gspI | General secretion pathway protein I. (129 aa) |
| | gspH | General secretion pathway protein H. (198 aa) |
| | gspG | General secretion pathway protein G. (144 aa) |
| | gspF | General secretion pathway protein F. (389 aa) |
| | gspE | General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (523 aa) |
| | gspD | General secretion pathway protein D. (712 aa) |
| | gspC | General secretion pathway protein C. (302 aa) |
| | secB | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (163 aa) |
