node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEW37696.1 | fabF | HMPREF0444_0482 | HMPREF0444_0280 | Acyl-ACP thioesterase; COG: COG3884; Pfam: PF01643; InterPro: IPR002864. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.928 |
EEW37701.1 | accB-2 | HMPREF0444_0487 | HMPREF0444_0281 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.466 |
EEW37701.1 | accC | HMPREF0444_0487 | HMPREF0444_0283 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.474 |
EEW37701.1 | fabD | HMPREF0444_0487 | HMPREF0444_0278 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR004410. | 0.658 |
EEW37701.1 | fabF | HMPREF0444_0487 | HMPREF0444_0280 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.599 |
EEW37701.1 | fabG | HMPREF0444_0487 | HMPREF0444_0279 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.520 |
EEW37701.1 | fabHA | HMPREF0444_0487 | HMPREF0444_0275 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Beta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.678 |
EEW37701.1 | fabZ | HMPREF0444_0487 | HMPREF0444_0282 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.634 |
accA | accB-2 | HMPREF0444_0285 | HMPREF0444_0281 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
accA | accC | HMPREF0444_0285 | HMPREF0444_0283 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
accA | accD | HMPREF0444_0285 | HMPREF0444_0284 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.999 |
accA | fabD | HMPREF0444_0285 | HMPREF0444_0278 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | [acyl-carrier-protein] S-malonyltransferase; COG: COG0331; Pfam: PF00698; InterPro: IPR004410. | 0.992 |
accA | fabF | HMPREF0444_0285 | HMPREF0444_0280 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.979 |
accA | fabG | HMPREF0444_0285 | HMPREF0444_0279 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.752 |
accA | fabHA | HMPREF0444_0285 | HMPREF0444_0275 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Beta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.989 |
accA | fabK | HMPREF0444_0285 | HMPREF0444_0277 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Putative enoyl-[acyl-carrier-protein] reductase II; COG: COG2070; Pfam: PF03060; InterPro: IPR004136. | 0.647 |
accA | fabZ | HMPREF0444_0285 | HMPREF0444_0282 | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.975 |
accB-2 | EEW37701.1 | HMPREF0444_0281 | HMPREF0444_0487 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG0300; Pfam: PF00106; InterPro: IPR016040; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.466 |
accB-2 | accA | HMPREF0444_0281 | HMPREF0444_0285 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.999 |
accB-2 | accC | HMPREF0444_0281 | HMPREF0444_0283 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.998 |