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oadA oadA oadB oadB EEW38227.1 EEW38227.1 gloA gloA pdhA pdhA pdhB pdhB aceF aceF lpdA lpdA acyP acyP accB-2 accB-2 accC accC accD accD accA accA pflB pflB EEW36448.1 EEW36448.1 EEW36428.1 EEW36428.1 ldhA2 ldhA2 EEW36746.1 EEW36746.1 oadB2 oadB2 oadA2 oadA2 EEW37053.1 EEW37053.1 sfcA2 sfcA2 atoB atoB ackA ackA EEW37554.1 EEW37554.1 EEW37687.1 EEW37687.1 sfcA sfcA pta pta pyk pyk aad aad pdxB pdxB EEW38266.1 EEW38266.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
oadAHMGL-like protein; COG: COG5016; Pfam: PF00682,PF02436; InterPro: IPR013785. (439 aa)
oadBSodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (375 aa)
EEW38227.1Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR013027. (455 aa)
gloAGlyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. (125 aa)
pdhAPyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (368 aa)
pdhBTransketolase, pyridine binding domain protein; COG: COG0022; Pfam: PF02779,PF02780; InterPro: IPR005475. (325 aa)
aceFPutative dihydrolipoyllysine-residue acetyltransferase; COG: COG0508; Pfam: PF00364,PF02817,PF00198; InterPro: IPR001078. (538 aa)
lpdADihydrolipoyl dehydrogenase; COG: COG1249; Pfam: PF07992,PF00070,PF02852; InterPro: IPR006258. (468 aa)
acyPAcylphosphatase; Pfam: PF00708; InterPro: IPR001792. (90 aa)
accB-2acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa)
accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (461 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (286 aa)
accAAcetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (255 aa)
pflBFormate C-acetyltransferase; COG: COG1882; Pfam: PF02901,PF01228; InterPro: IPR005949. (742 aa)
EEW36448.1Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. (212 aa)
EEW36428.1Hypothetical protein; COG: COG3875. (453 aa)
ldhA2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (324 aa)
EEW36746.1Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279. (238 aa)
oadB2Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (373 aa)
oadA2HMGL-like protein; COG: COG5016; Pfam: PF00682,PF02436; InterPro: IPR000891. (464 aa)
EEW37053.1Rhodanese-like protein; COG: COG0607; Pfam: PF00581; InterPro: IPR001763. (94 aa)
sfcA2Malic enzyme, NAD binding domain protein; COG: COG0281; Pfam: PF00390,PF03949; InterPro: IPR016040. (564 aa)
atoBacetyl-CoA C-acetyltransferase; COG: COG0183; Pfam: PF00108,PF02803; InterPro: IPR002155; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
EEW37554.1COG: COG1053; Pfam: PF00890; InterPro: IPR010960; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (505 aa)
EEW37687.1AMP-binding enzyme; Pfam: PF00501; InterPro: IPR000873. (516 aa)
sfcAMalic enzyme, NAD binding domain protein; COG: COG0281; Pfam: PF00390,PF03949; InterPro: IPR016040. (541 aa)
ptaPhosphate acetyltransferase; COG: COG0280; Pfam: PF01515; InterPro: IPR002505. (329 aa)
pykPyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family. (472 aa)
aadAlcohol dehydrogenase, iron-dependent; Pfam: PF00465; InterPro: IPR001670; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (876 aa)
pdxB4-phosphoerythronate dehydrogenase; COG: COG1052; Pfam: PF00389,PF02826; InterPro: IPR006139; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
EEW38266.1Hypothetical protein; 4.1.1.49. (549 aa)
Your Current Organism:
Granulicatella adiacens
NCBI taxonomy Id: 638301
Other names: G. adiacens ATCC 49175, Granulicatella adiacens ATCC 49175, Granulicatella adiacens str. ATCC 49175, Granulicatella adiacens strain ATCC 49175
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