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glyA glyA Snov_0592 Snov_0592 Snov_1529 Snov_1529 Snov_1644 Snov_1644 Snov_2113 Snov_2113 Snov_2530 Snov_2530 Snov_3011 Snov_3011 Snov_3118 Snov_3118 metXA metXA Snov_3474 Snov_3474 Snov_3710 Snov_3710
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
Snov_0592TIGRFAM: threonine synthase; KEGG: azc:AZC_2239 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (469 aa)
Snov_1529PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpd:RPD_2099 hypothetical protein. (318 aa)
Snov_1644KEGG: xau:Xaut_4294 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. (408 aa)
Snov_2113PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: xau:Xaut_4110 pyridoxal-5'-phosphate-dependent protein beta subunit. (329 aa)
Snov_2530PFAM: aminotransferase class V; KEGG: rme:Rmet_5630 aminotransferase, class V. (401 aa)
Snov_3011TIGRFAM: L-serine dehydratase 1; KEGG: msl:Msil_1803 L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)
Snov_3118TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: bra:BRADO5568 phosphoserine phosphatase (PSP) (O-phosphoserine phosphohydrolase) (PSPase); PFAM: Haloacid dehalogenase domain protein hydrolase. (297 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (396 aa)
Snov_3474KEGG: azc:AZC_0228 methionine biosynthesis MetW protein; TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein. (227 aa)
Snov_3710Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (350 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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