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mscL mscL Snov_0299 Snov_0299 Snov_0870 Snov_0870 cysS cysS Snov_0965 Snov_0965 Snov_0966 Snov_0966 Snov_0967 Snov_0967 Snov_0968 Snov_0968 Snov_0969 Snov_0969 Snov_0970 Snov_0970 Snov_0971 Snov_0971 soxA soxA Snov_0973 Snov_0973 Snov_0974 Snov_0974 Snov_0976 Snov_0976 Snov_0978 Snov_0978 Snov_0979 Snov_0979 Snov_0980 Snov_0980 Snov_0981 Snov_0981 Snov_0982 Snov_0982 Snov_0983 Snov_0983 Snov_0984 Snov_0984 Snov_0985 Snov_0985 Snov_0986 Snov_0986 Snov_0987 Snov_0987 Snov_0988 Snov_0988 Snov_1167 Snov_1167 Snov_1371 Snov_1371 Snov_1396 Snov_1396 Snov_1401 Snov_1401 Snov_1403 Snov_1403 Snov_1893 Snov_1893 Snov_1975 Snov_1975 Snov_1976 Snov_1976 Snov_1977 Snov_1977 Snov_1978 Snov_1978 Snov_1979 Snov_1979 Snov_1980 Snov_1980 Snov_1981 Snov_1981 Snov_1982 Snov_1982 Snov_2003 Snov_2003 Snov_2025 Snov_2025 Snov_2227 Snov_2227 Snov_2229 Snov_2229 Snov_2319 Snov_2319 Snov_2320 Snov_2320 Snov_2321 Snov_2321 Snov_2322 Snov_2322 Snov_2323 Snov_2323 Snov_2324 Snov_2324 cysA cysA Snov_2622 Snov_2622 Snov_2887 Snov_2887 Snov_3268 Snov_3268 Snov_3269 Snov_3269 cysC cysC Snov_3280 Snov_3280 Snov_3281 Snov_3281 Snov_3282 Snov_3282 Snov_3283 Snov_3283 Snov_3284 Snov_3284 Snov_3285 Snov_3285 Snov_3286 Snov_3286 Snov_3287 Snov_3287 Snov_3610 Snov_3610 Snov_3623 Snov_3623 Snov_3927 Snov_3927 Snov_3928 Snov_3928 Snov_3929 Snov_3929 Snov_3955 Snov_3955 Snov_4278 Snov_4278 ahcY ahcY metZ metZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mscLLarge conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (142 aa)
Snov_0299KEGG: azc:AZC_0709 cysteine synthase K/M; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (325 aa)
Snov_0870Alkanesulfonate monooxygenase; KEGG: ara:Arad_8153 FMNH2-dependent aliphatic sulfonate monooxygenase protein; PFAM: Luciferase-like, subgroup. (362 aa)
cysSTIGRFAM: cysteinyl-tRNA synthetase; KEGG: bbt:BBta_3498 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (464 aa)
Snov_0965PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; KEGG: xau:Xaut_1514 flavocytochrome c sulphide dehydrogenase flavin-binding. (424 aa)
Snov_0966PFAM: Domain of unknown function DUF1791; KEGG: xau:Xaut_1515 hypothetical protein. (173 aa)
Snov_0967KEGG: xau:Xaut_1517 putative cytochrome. (223 aa)
Snov_0968PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: xau:Xaut_1518 oxidoreductase molybdopterin binding. (428 aa)
Snov_0969PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: xau:Xaut_1519 5'-nucleotidase domain-containing protein; Belongs to the 5'-nucleotidase family. (564 aa)
Snov_0970PFAM: Sulphur oxidation protein SoxZ; KEGG: xau:Xaut_1520 sulphur oxidation protein SoxZ. (109 aa)
Snov_0971KEGG: xau:Xaut_1521 sulfur oxidation protein SoxY. (154 aa)
soxAConserved hypothetical protein; C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain. Some electrons may be used for reductive CO(2) fixation. (289 aa)
Snov_0973KEGG: xau:Xaut_1523 hypothetical protein. (208 aa)
Snov_0974KEGG: xau:Xaut_1524 hypothetical protein. (185 aa)
Snov_0976KEGG: rpd:RPD_4261 hypothetical protein. (129 aa)
Snov_0978PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: xau:Xaut_1528 protein of unknown function DUF395 YeeE/YedE. (375 aa)
Snov_0979PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: azc:AZC_2083 YeeE/YedE family protein. (137 aa)
Snov_0980PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: azc:AZC_2084 YeeE/YedE family protein. (142 aa)
Snov_0981Transcriptional regulator, ArsR family; KEGG: smd:Smed_1609 regulatory protein ArsR; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR. (118 aa)
Snov_0982KEGG: pde:Pden_4706 beta-lactamase domain-containing protein. (293 aa)
Snov_0983KEGG: rce:RC1_2567 hypothetical protein. (72 aa)
Snov_0984KEGG: gdj:Gdia_2699 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR. (129 aa)
Snov_0985PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: gdj:Gdia_2700 peroxiredoxin. (217 aa)
Snov_0986KEGG: swi:Swit_3744 beta-lactamase domain-containing protein. (307 aa)
Snov_0987PFAM: protein of unknown function DUF442; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bac:BamMC406_1667 hypothetical protein. (563 aa)
Snov_0988PFAM: protein of unknown function DUF81; KEGG: gbe:GbCGDNIH1_0868 putative permease. (261 aa)
Snov_1167PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; flavodoxin/nitric oxide synthase; PepSY-associated TM helix domain protein; Oxidoreductase FAD-binding domain protein; KEGG: pde:Pden_3290 oxidoreductase FAD/NAD(P)-binding subunit. (735 aa)
Snov_1371PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. (325 aa)
Snov_1396TIGRFAM: cystathionine beta-lyase; KEGG: azc:AZC_1584 cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (403 aa)
Snov_1401Rhodanese domain protein; KEGG: azc:AZC_2826 rhodanese-related sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (282 aa)
Snov_1403PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: xau:Xaut_4677 pyridoxal-5'-phosphate-dependent protein beta subunit. (343 aa)
Snov_1893MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (249 aa)
Snov_1975PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: lch:Lcho_0068 2Fe-2S iron-sulfur cluster binding domain-containing protein. (152 aa)
Snov_1976PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: lch:Lcho_0067 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding. (732 aa)
Snov_1977KEGG: mno:Mnod_4567 cytochrome c class I. (107 aa)
Snov_1978PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD dependent oxidoreductase; KEGG: met:M446_3049 flavocytochrome c sulphide dehydrogenase flavin-binding. (413 aa)
Snov_1979KEGG: lch:Lcho_0066 putative cytochrome c, putative SoxX protein. (138 aa)
Snov_1980KEGG: mno:Mnod_7669 sulfur oxidation protein SoxY. (157 aa)
Snov_1981PFAM: Sulphur oxidation protein SoxZ; KEGG: lch:Lcho_0064 sulphur oxidation protein SoxZ. (106 aa)
Snov_1982Putative diheme cytochrome c; C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain. Some electrons may be used for reductive CO(2) fixation. (256 aa)
Snov_2003KEGG: mlo:mlr4651 cysteine synthase; TIGRFAM: cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (361 aa)
Snov_2025TIGRFAM: serine O-acetyltransferase; KEGG: rpc:RPC_3144 serine O-acetyltransferase; PFAM: serine acetyltransferase domain protein; transferase hexapeptide repeat containing protein. (283 aa)
Snov_2227PFAM: CoA-binding domain protein; KEGG: rlg:Rleg_1328 CoA-binding domain protein. (151 aa)
Snov_2229TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (430 aa)
Snov_2319KEGG: rpt:Rpal_0858 hypothetical protein. (269 aa)
Snov_2320Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1244 aa)
Snov_2321KEGG: rpc:RPC_2401 hypothetical protein. (76 aa)
Snov_2322TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: azc:AZC_4340 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (308 aa)
Snov_2323Transcriptional regulator, ArsR family; KEGG: azc:AZC_4339 regulatory protein; PFAM: Methyltransferase type 11; regulatory protein ArsR; SMART: regulatory protein ArsR. (338 aa)
Snov_2324PFAM: protein of unknown function UPF0066; KEGG: mno:Mnod_5557 protein of unknown function UPF0066. (188 aa)
cysASulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (366 aa)
Snov_2622PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nar:Saro_1061 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (371 aa)
Snov_2887PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nar:Saro_1061 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (372 aa)
Snov_3268PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: xau:Xaut_2672 oxidoreductase molybdopterin binding. (405 aa)
Snov_3269KEGG: xau:Xaut_2671 putative sulfite:cytochrome c oxidoreductase subunit B. (108 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (643 aa)
Snov_3280PFAM: phosphoadenosine phosphosulfate reductase; KEGG: rpb:RPB_1043 sulfate adenylyltransferase subunit 2. (268 aa)
Snov_3281KEGG: rpb:RPB_1400 hypothetical protein. (102 aa)
Snov_3282PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: rpc:RPC_4013 nitrite and sulphite reductase 4Fe-4S region. (551 aa)
Snov_3283PFAM: conserved hypothetical protein; KEGG: rpd:RPD_1382 hypothetical protein. (169 aa)
Snov_3284Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (248 aa)
Snov_3285KEGG: nha:Nham_3560 thiosulphate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1. (339 aa)
Snov_3286Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (286 aa)
Snov_3287KEGG: xau:Xaut_1392 sulfate ABC transporter, inner membrane subunit CysW; TIGRFAM: sulfate ABC transporter, inner membrane subunit CysW; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component. (280 aa)
Snov_3610PFAM: amidohydrolase; KEGG: mva:Mvan_0863 amidohydrolase. (511 aa)
Snov_3623PFAM: amidohydrolase; KEGG: rle:pRL100068 putative aminohydrolase. (500 aa)
Snov_3927KEGG: xau:Xaut_2331 sulfate ABC transporter, periplasmic sulfate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1. (363 aa)
Snov_3928Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (273 aa)
Snov_3929KEGG: azc:AZC_3734 sulfate ABC transporter permease protein; TIGRFAM: sulfate ABC transporter, inner membrane subunit CysW; sulfate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component. (295 aa)
Snov_3955TIGRFAM: S-adenosylmethionine synthetase; KEGG: xau:Xaut_1816 methionine adenosyltransferase; PFAM: S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. (397 aa)
Snov_4278PFAM: amidohydrolase; KEGG: met:M446_3497 amidohydrolase. (513 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (468 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (401 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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