STRINGSTRING
glsA glsA Snov_0337 Snov_0337 Snov_0414 Snov_0414 Snov_0455 Snov_0455 Snov_0457 Snov_0457 Snov_0458 Snov_0458 Snov_0935 Snov_0935 guaA guaA purF purF glmS glmS pyrG pyrG purQ purQ Snov_2222 Snov_2222 carA carA Snov_2490 Snov_2490 cobB cobB cobQ cobQ Snov_2713 Snov_2713 Snov_3392 Snov_3392 Snov_3421 Snov_3421 hisH hisH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
glsAGlutaminase; KEGG: rpd:RPD_1383 glutaminase; PFAM: Glutaminase, core; Belongs to the glutaminase family. (327 aa)
Snov_0337Glutamate--putrescine ligase; KEGG: azc:AZC_4442 glutamine synthetase family protein; PFAM: glutamine synthetase catalytic region. (466 aa)
Snov_0414KEGG: met:M446_4572 glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (344 aa)
Snov_0455KEGG: azc:AZC_1499 glutamine synthetase III; TIGRFAM: glutamine synthetase, type III; PFAM: glutamine synthetase catalytic region. (433 aa)
Snov_0457PFAM: glutamate synthase alpha subunit domain protein; KEGG: azc:AZC_1501 putative oxidoreductase. (236 aa)
Snov_0458PFAM: glutamine amidotransferase class-II; KEGG: azc:AZC_1502 amidophosphoribosyltransferase. (293 aa)
Snov_0935Glutamate--putrescine ligase; KEGG: azc:AZC_3648 putative glutamine synthetase protein; PFAM: glutamine synthetase catalytic region. (469 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (533 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (499 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (232 aa)
Snov_2222KEGG: azc:AZC_1601 glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (469 aa)
carAKEGG: xau:Xaut_1243 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (400 aa)
Snov_2490PFAM: protein of unknown function DUF1355; KEGG: xau:Xaut_2945 hypothetical protein. (690 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (436 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (489 aa)
Snov_2713KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein. (1576 aa)
Snov_3392PFAM: glutamine amidotransferase class-I; KEGG: mno:Mnod_0664 glutamine amidotransferase class-I. (249 aa)
Snov_3421PFAM: peptidase C26; KEGG: mpt:Mpe_A1900 glutamine amidotransferase-like protein. (267 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (220 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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