node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Snov_1365 | Snov_1371 | Snov_1365 | Snov_1371 | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. | 0.824 |
Snov_1365 | Snov_2229 | Snov_1365 | Snov_2229 | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.867 |
Snov_1365 | Snov_2320 | Snov_1365 | Snov_2320 | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
Snov_1365 | Snov_2322 | Snov_1365 | Snov_2322 | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: azc:AZC_4340 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.651 |
Snov_1365 | asd | Snov_1365 | Snov_2825 | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.972 |
Snov_1365 | metXA | Snov_1365 | Snov_3473 | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.976 |
Snov_1371 | Snov_1365 | Snov_1371 | Snov_1365 | PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | 0.824 |
Snov_1371 | Snov_2229 | Snov_1371 | Snov_2229 | PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.911 |
Snov_1371 | Snov_2320 | Snov_1371 | Snov_2320 | PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.941 |
Snov_1893 | Snov_2320 | Snov_1893 | Snov_2320 | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.516 |
Snov_2229 | Snov_1365 | Snov_2229 | Snov_1365 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | 0.867 |
Snov_2229 | Snov_1371 | Snov_2229 | Snov_1371 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. | 0.911 |
Snov_2229 | Snov_2320 | Snov_2229 | Snov_2320 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |
Snov_2229 | metXA | Snov_2229 | Snov_3473 | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.990 |
Snov_2320 | Snov_1365 | Snov_2320 | Snov_1365 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: azc:AZC_1848 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. | 0.948 |
Snov_2320 | Snov_1371 | Snov_2320 | Snov_1371 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homocysteine S-methyltransferase; KEGG: rlg:Rleg_0984 homocysteine S-methyltransferase. | 0.941 |
Snov_2320 | Snov_1893 | Snov_2320 | Snov_1893 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.516 |
Snov_2320 | Snov_2229 | Snov_2320 | Snov_2229 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azc:AZC_2180 O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.962 |
Snov_2320 | Snov_2322 | Snov_2320 | Snov_2322 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: azc:AZC_4340 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.999 |
Snov_2320 | Snov_2382 | Snov_2320 | Snov_2382 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU1327 homocysteine S-methyltransferase domain-containing protein. | 0.440 |