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| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (149 aa) |
| | eutC | KEGG: azc:AZC_3565 ethanolamine ammonia-lyase small subunit; PFAM: Ethanolamine ammonia-lyase light chain; Belongs to the EutC family. (271 aa) |
| | Snov_1558 | KEGG: xau:Xaut_2421 YbaK/EbsC protein; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa) |
| | Snov_1581 | KEGG: xau:Xaut_0519 malonyl-CoA decarboxylase; PFAM: Malonyl-CoA decarboxylase. (455 aa) |
| | Snov_1592 | PFAM: MmgE/PrpD family protein; KEGG: bxe:Bxe_C1226 hypothetical protein. (478 aa) |
| | Snov_1607 | PFAM: MmgE/PrpD family protein; KEGG: bxe:Bxe_C1226 hypothetical protein. (475 aa) |
| | Snov_1608 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: azc:AZC_1934 lactoylglutathione lyase. (140 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | Snov_1644 | KEGG: xau:Xaut_4294 threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein. (408 aa) |
| | Snov_1646 | Porphobilinogen synthase; KEGG: xau:Xaut_4295 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (353 aa) |
| | Snov_1647 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: azc:AZC_1544 putative enoyl-CoA hydratase. (370 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (173 aa) |
| | Snov_1718 | PFAM: Lytic transglycosylase catalytic; KEGG: oan:Oant_0077 lytic transglycosylase catalytic. (183 aa) |
| | rlpA-2 | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (357 aa) |
| | ispDF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (402 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (504 aa) |
| | trpC | KEGG: azc:AZC_2205 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (270 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (166 aa) |
| | Snov_1847 | TIGRFAM: methylmalonyl-CoA epimerase; KEGG: xau:Xaut_4617 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (134 aa) |
| | ilvD | TIGRFAM: dihydroxy-acid dehydratase; KEGG: met:M446_5056 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (575 aa) |
| | Snov_1919 | KEGG: met:M446_1318 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (573 aa) |
| | Snov_1921 | PFAM: dihydrodipicolinate synthetase; KEGG: azc:AZC_0731 dihydrodipicolinate synthetase; Belongs to the DapA family. (314 aa) |
| | Snov_2113 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: xau:Xaut_4110 pyridoxal-5'-phosphate-dependent protein beta subunit. (329 aa) |
| | Snov_2135 | PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: azc:AZC_2949 cytochrome c biogenesis protein. (243 aa) |
| | Snov_2143 | KEGG: nwi:Nwi_2167 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | nnrE | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (496 aa) |
| | Snov_2816 | PFAM: Heparinase II/III family protein; KEGG: azc:AZC_4697 hypothetical protein. (576 aa) |
| | adc | Acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family. (246 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (603 aa) |
| | Snov_2983 | KEGG: azc:AZC_3488 glyoxylate carboligase; TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (588 aa) |
| | Snov_2999 | KEGG: azc:AZC_0561 4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase. (214 aa) |
| | Snov_3011 | TIGRFAM: L-serine dehydratase 1; KEGG: msl:Msil_1803 L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | Snov_3072 | KEGG: xau:Xaut_3077 fructose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I. (340 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (168 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (363 aa) |
| | Snov_3156 | PFAM: Lytic transglycosylase catalytic; KEGG: oan:Oant_1733 lytic transglycosylase catalytic. (175 aa) |
| | Snov_3163 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1154 aa) |
| | Snov_3187 | Phosphoketolase; KEGG: bid:Bind_2204 putative phosphoketolase; PFAM: Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase. (790 aa) |
| | Snov_3199 | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (300 aa) |
| | Snov_2281 | TIGRFAM: para-aminobenzoate synthase, subunit I; KEGG: mno:Mnod_0053 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein. (474 aa) |
| | Snov_2291 | KEGG: xau:Xaut_0519 malonyl-CoA decarboxylase; PFAM: Malonyl-CoA decarboxylase. (458 aa) |
| | ilvD-2 | TIGRFAM: dihydroxy-acid dehydratase; KEGG: mpo:Mpop_2797 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (610 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (928 aa) |
| | Snov_2442 | PFAM: ribonuclease T2; KEGG: xau:Xaut_2731 ribonuclease T2; Belongs to the RNase T2 family. (223 aa) |
| | Snov_2505 | PFAM: phosphonate metabolism PhnJ; KEGG: azc:AZC_3395 putative C-P (carbon-phosphorus) lyase component protein. (363 aa) |
| | Snov_2522 | PFAM: dihydrodipicolinate synthetase; KEGG: mag:amb2543 dihydrodipicolinate synthase; Belongs to the DapA family. (300 aa) |
| | Snov_2537 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: azc:AZC_1808 enoyl-CoA hydratase. (267 aa) |
| | cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (324 aa) |
| | Snov_2637 | PFAM: alanine racemase domain protein; KEGG: pde:Pden_3919 alanine racemase domain-containing protein. (391 aa) |
| | Snov_2638 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mes:Meso_3309 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (316 aa) |
| | Snov_2718 | PFAM: dihydrodipicolinate synthetase; KEGG: smd:Smed_4167 dihydrodipicolinate synthetase; Belongs to the DapA family. (298 aa) |
| | Snov_2748 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: msl:Msil_3783 glyoxalase/bleomycin resistance protein/dioxygenase. (131 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (386 aa) |
| | Snov_2805 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (234 aa) |
| | Snov_0063 | PFAM: Pyridoxal-dependent decarboxylase; KEGG: smd:Smed_4423 pyridoxal-dependent decarboxylase. (477 aa) |
| | Snov_0079 | PFAM: protein of unknown function UPF0047; KEGG: rpb:RPB_4567 hypothetical protein. (154 aa) |
| | Snov_0084 | KEGG: azc:AZC_1833 dTDP-D-glucose-4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa) |
| | Snov_0115 | KEGG: atc:AGR_L_3190 putative dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (601 aa) |
| | Snov_0118 | PFAM: dihydrodipicolinate synthetase; KEGG: xau:Xaut_1021 dihydrodipicolinate synthetase; Belongs to the DapA family. (310 aa) |
| | Snov_0119 | KEGG: xau:Xaut_1022 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (586 aa) |
| | Snov_0155 | Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be involved in a degradation pathway that converts t3LHyp to L-proline, which would allow S.novella to grow on t3LHyp as a sole carbon source. (345 aa) |
| | Snov_0156 | Mandelate racemase/muconate lactonizing protein; Catalyzes the dehydration of cis-3-hydroxy-L-proline (c3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be involved in a degradation pathway that converts c3LHyp to L-proline, which would allow S.novella to grow on c3LHyp as a sole carbon source. (367 aa) |
| | Snov_0159 | PFAM: dihydrodipicolinate synthetase; KEGG: mlo:mll3981 dihydrodipicolinate synthase; Belongs to the DapA family. (298 aa) |
| | Snov_0175 | PFAM: dihydrodipicolinate synthetase; KEGG: bbr:BB4720 putative dihydrodipicolinate synthase; Belongs to the DapA family. (309 aa) |
| | Snov_0200 | PFAM: amidohydrolase 2; KEGG: swi:Swit_1683 amidohydrolase 2. (341 aa) |
| | Snov_0217 | PFAM: amidohydrolase 2; KEGG: pat:Patl_0847 aminocarboxymuconate-semialdehyde decarboxylase. (363 aa) |
| | fabA | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (169 aa) |
| | Snov_0250 | KEGG: azc:AZC_0138 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein. (282 aa) |
| | Snov_0279 | Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (210 aa) |
| | Snov_0296 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (409 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (283 aa) |
| | Snov_0364 | PFAM: MaoC domain protein dehydratase; KEGG: bxe:Bxe_B2585 hypothetical protein. (276 aa) |
| | Snov_0374 | KEGG: bja:bll0499 citrate lyase beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (297 aa) |
| | Snov_0427 | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (361 aa) |
| | cbbL | Ribulose-bisphosphate carboxylase; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (489 aa) |
| | Snov_0429 | KEGG: bbt:BBta_0452 ribulose 1,5-bisphosphate carboxylase small subunit; PFAM: ribulose bisphosphate carboxylase small chain. (139 aa) |
| | Snov_0580 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: xau:Xaut_3308 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (299 aa) |
| | Snov_0592 | TIGRFAM: threonine synthase; KEGG: azc:AZC_2239 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (469 aa) |
| | Snov_0740 | KEGG: mrd:Mrad2831_2016 formaldehyde-activating enzyme; TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae). (179 aa) |
| | Snov_0744 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | Snov_0754 | PFAM: transcriptional coactivator/pterin dehydratase; KEGG: xau:Xaut_4534 transcriptional coactivator/pterin dehydratase. (126 aa) |
| | Snov_0761 | PFAM: protein of unknown function DUF556; KEGG: xau:Xaut_4098 hypothetical protein. (243 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (133 aa) |
| | Snov_0815 | Isocitrate lyase; KEGG: scl:sce8726 hypothetical protein; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. (432 aa) |
| | Snov_0885 | KEGG: avi:Avi_8089 PEP phosphonomutase. (273 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (348 aa) |
| | psd | Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (232 aa) |
| | Snov_0941 | PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: bbt:BBta_3521 putative 3-hydroxymyristoyl-acyl carrier protein dehydratase FabZ-like protein. (171 aa) |
| | Snov_0975 | PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: xau:Xaut_1525 cytochrome c biogenesis protein transmembrane region. (244 aa) |
| | Snov_1020 | Aconitate hydratase domain protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (867 aa) |
| | Snov_1031 | PFAM: carbonic anhydrase; KEGG: mno:Mnod_7305 carbonic anhydrase. (241 aa) |
| | Snov_1050 | KEGG: xau:Xaut_0032 formaldehyde-activating protein; TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae). (168 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (379 aa) |
| | Snov_1125 | PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: mes:Meso_3070 glutathione-dependent formaldehyde-activating, GFA. (137 aa) |
| | Snov_1130 | O-pyrocatechuate decarboxylase; KEGG: xau:Xaut_2054 amidohydrolase 2; PFAM: amidohydrolase 2. (317 aa) |
| | Snov_1232 | PFAM: MmgE/PrpD family protein; KEGG: met:M446_0113 MmgE/PrpD family protein. (465 aa) |
| | Snov_1249 | PFAM: ThiJ/PfpI domain protein; KEGG: art:Arth_3900 ThiJ/PfpI domain-containing protein. (231 aa) |
| | Snov_1273 | UbiD family decarboxylase; KEGG: sth:STH1564 putative 4-hydroxybenzoate decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; Belongs to the UbiD family. (451 aa) |
| | Snov_4460 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (499 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (370 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (434 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (537 aa) |
| | Snov_4343 | PFAM: ThiJ/PfpI domain protein; KEGG: azc:AZC_2782 type 1 glutamine amidotransferase. (266 aa) |
| | Snov_4324 | KEGG: pol:Bpro_5111 dihydroxyacid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (556 aa) |
| | uxuA | Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (404 aa) |
| | Snov_4290 | Galactarate dehydratase; KEGG: azc:AZC_3340 altronate hydrolase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein. (512 aa) |
| | Snov_4286 | KEGG: bte:BTH_II2235 citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (301 aa) |
| | Snov_4260 | PFAM: Ureidoglycolate hydrolase; KEGG: bpl:BURPS1106A_3456 ureidoglycolate hydrolase. (170 aa) |
| | Snov_4254 | PFAM: MmgE/PrpD family protein; KEGG: oan:Oant_4513 MmgE/PrpD family protein. (457 aa) |
| | Snov_4219 | KEGG: swi:Swit_1864 diaminopropionate ammonia-lyase; TIGRFAM: diaminopropionate ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (403 aa) |
| | Snov_4095 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rsk:RSKD131_4204 short chain enoyl-CoA hydratase. (264 aa) |
| | Snov_4079 | KEGG: acr:Acry_2434 putative aldolase; PFAM: class II aldolase/adducin family protein. (210 aa) |
| | Snov_4074 | PFAM: KDPG and KHG aldolase; KEGG: azc:AZC_4410 2-keto-3-deoxy-6-phosphogluconate aldolase. (208 aa) |
| | Snov_4071 | 2-keto-4-pentenoate hydratase-like protein; KEGG: bja:bll5831 putative hydratase. (260 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (242 aa) |
| | Snov_3939 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: azc:AZC_0333 ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (376 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (361 aa) |
| | Snov_3860 | PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: bid:Bind_1794 thiamine pyrophosphate binding domain-containing protein. (548 aa) |
| | Snov_3859 | KEGG: avi:Avi_2104 hypothetical protein. (224 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (261 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (220 aa) |
| | hisB | KEGG: azc:AZC_4502 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | Snov_3819 | PFAM: MltA domain protein; 3D domain protein; KEGG: xau:Xaut_2049 MltA domain-containing protein. (416 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (350 aa) |
| | gmd | NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (338 aa) |
| | Snov_3734 | KEGG: met:M446_4784 hypothetical protein. (133 aa) |
| | Snov_3710 | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (350 aa) |
| | Snov_3661 | KEGG: mno:Mnod_3435 ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit-like; Belongs to the RuBisCO large chain family. (420 aa) |
| | Snov_3648 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: har:HEAR2723 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | Snov_3631 | KEGG: mno:Mnod_7300 hypothetical protein. (119 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (555 aa) |
| | hutH | TIGRFAM: histidine ammonia-lyase; KEGG: ccr:CC_0959 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (511 aa) |
| | Snov_3532 | PFAM: pyruvate carboxyltransferase; KEGG: acr:Acry_2695 pyruvate carboxyltransferase. (307 aa) |
| | Snov_3528 | KEGG: fal:FRAAL4864 hypothetical protein. (159 aa) |
| | Snov_3518 | PFAM: MaoC domain protein dehydratase; KEGG: MaoC domain protein dehydratase. (172 aa) |
| | Snov_3499 | PFAM: protein of unknown function DUF111; KEGG: mrd:Mrad2831_1358 hypothetical protein. (428 aa) |
| | Snov_3489 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (894 aa) |
| | argH | KEGG: xau:Xaut_1738 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase. (458 aa) |
| | Snov_3421 | PFAM: peptidase C26; KEGG: mpt:Mpe_A1900 glutamine amidotransferase-like protein. (267 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | Snov_3402 | ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (180 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (612 aa) |
| | Snov_3384 | KEGG: mpo:Mpop_3212 OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; hydroxyisourate hydrolase; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Transthyretin. (301 aa) |
| | Snov_3365 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bja:blr2408 hypothetical protein. (152 aa) |
| | Snov_3276 | KEGG: azc:AZC_3736 citrate lyase beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (299 aa) |
| | Snov_3261 | PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: xca:xccb100_0162 hypothetical protein. (263 aa) |
| | Snov_3242 | KEGG: bra:BRADO6988 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (584 aa) |
| | Snov_1276 | UbiD family decarboxylase; KEGG: mno:Mnod_8148 carboxylyase-related protein; TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; Belongs to the UbiD family. (545 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (205 aa) |
| | moaA-2 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (348 aa) |
| | Snov_1350 | PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: pde:Pden_2817 glutathione-dependent formaldehyde-activating, GFA. (130 aa) |
| | Snov_1360 | PFAM: carbonic anhydrase; KEGG: mrd:Mrad2831_6116 carbonic anhydrase. (236 aa) |
| | Snov_1396 | TIGRFAM: cystathionine beta-lyase; KEGG: azc:AZC_1584 cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (403 aa) |
| | Snov_1404 | KEGG: xau:Xaut_4676 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein. (479 aa) |
| | Snov_1529 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpd:RPD_2099 hypothetical protein. (318 aa) |
| | Snov_1553 | KEGG: azc:AZC_3564 ethanolamine ammonia-lyase large subunit; PFAM: Ethanolamine ammonia lyase large subunit. (462 aa) |
