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atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH Snov_3494 Snov_3494 Snov_3497 Snov_3497 selA selA Snov_3643 Snov_3643 Snov_3695 Snov_3695 Snov_3704 Snov_3704 Snov_3716 Snov_3716 Snov_3734 Snov_3734 Snov_3740 Snov_3740 nadE-2 nadE-2 Snov_3743 Snov_3743 Snov_3801 Snov_3801 rho rho coaE coaE dnaQ dnaQ coaA coaA cmk cmk polA polA Snov_3877 Snov_3877 Snov_3881 Snov_3881 nusA nusA purD purD accD accD Snov_3944 Snov_3944 Snov_3975 Snov_3975 pyrF pyrF queG queG Snov_4037 Snov_4037 Snov_4180 Snov_4180 Snov_4211 Snov_4211 Snov_4237 Snov_4237 Snov_4266 Snov_4266 Snov_4268 Snov_4268 dnaE2 dnaE2 atpB atpB atpE atpE atpF atpF atpF-2 atpF-2 dnaX dnaX Snov_4502 Snov_4502 apaG apaG Snov_0053 Snov_0053 Snov_0065 Snov_0065 Snov_0068 Snov_0068 Snov_0083 Snov_0083 Snov_0085 Snov_0085 upp upp murA murA kdsB kdsB Snov_0296 Snov_0296 dut dut Snov_0352 Snov_0352 Snov_0396 Snov_0396 folD folD purU purU nadA nadA Snov_0491 Snov_0491 Snov_0492 Snov_0492 Snov_0558 Snov_0558 Snov_0561 Snov_0561 Snov_0577 Snov_0577 Snov_0599 Snov_0599 Snov_0687 Snov_0687 Snov_0819 Snov_0819 Snov_0825 Snov_0825 nadE nadE Snov_0921 Snov_0921 guaB guaB guaA guaA Snov_0992 Snov_0992 purF purF Snov_1078 Snov_1078 gmk gmk Snov_1098 Snov_1098 ndk ndk purN purN purM purM Snov_1186 Snov_1186 Snov_1191 Snov_1191 Snov_1209 Snov_1209 Snov_1324 Snov_1324 nadK nadK nusG nusG rpoB rpoB rpoC rpoC adk adk rpoA rpoA dinB dinB pyrC pyrC pyrB pyrB Snov_1535 Snov_1535 Snov_1560 Snov_1560 Snov_1562 Snov_1562 Snov_1612 Snov_1612 rpoZ rpoZ pyrE pyrE nusB nusB coaD coaD queA queA tgt tgt tmk tmk Snov_1771 Snov_1771 Snov_1787 Snov_1787 Snov_1793 Snov_1793 queF queF glmU glmU pyrG pyrG pyrH pyrH Snov_1840 Snov_1840 serS serS Snov_1936 Snov_1936 Snov_1972 Snov_1972 gpt gpt Snov_2084 Snov_2084 Snov_2143 Snov_2143 purC purC purS purS purQ purQ purL purL Snov_2151 Snov_2151 Snov_2168 Snov_2168 Snov_2178 Snov_2178 ackA ackA pncB pncB rpoD rpoD dnaG dnaG carA carA carB carB prs prs rpoH rpoH accA accA Snov_2799 Snov_2799 acsA acsA purH purH purA purA Snov_3078 Snov_3078 Snov_3083 Snov_3083 thyA thyA purE purE purK purK Snov_3206 Snov_3206 Snov_3210 Snov_3210 Snov_3266 Snov_3266 priA priA Snov_3337 Snov_3337 Snov_3386 Snov_3386 Snov_3407 Snov_3407 nadD nadD Snov_3457 Snov_3457
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query proteins and first shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (477 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa)
Snov_3494PFAM: NAD-dependent epimerase/dehydratase; KEGG: bbt:BBta_5514 putative dihydrokaempferol 4-reductase (NAD-dependent epimerase/dehydratase). (341 aa)
Snov_3497PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mrd:Mrad2831_1356 putative circadian phase modifier CpmA-like protein. (220 aa)
selAL-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (475 aa)
Snov_3643KEGG: pag:PLES_16511 putative sigma-70 factor, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2. (164 aa)
Snov_3695KEGG: met:M446_4806 RNA polymerase factor sigma-32; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein. (293 aa)
Snov_3704Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (205 aa)
Snov_3716PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: azc:AZC_0069 putative selenophosphate synthetase-related protein. (332 aa)
Snov_3734KEGG: met:M446_4784 hypothetical protein. (133 aa)
Snov_3740PFAM: NUDIX hydrolase; KEGG: mjl:Mjls_2909 NUDIX hydrolase. (153 aa)
nadE-2NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (680 aa)
Snov_3743PFAM: protein of unknown function DUF344; KEGG: gbe:GbCGDNIH1_1622 polyphosphate kinase. (306 aa)
Snov_3801KEGG: xau:Xaut_1448 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. (340 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (421 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (232 aa)
coaATIGRFAM: pantothenate kinase; KEGG: azc:AZC_4496 pantothenate kinase. (320 aa)
cmkKEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (209 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (981 aa)
Snov_3877KEGG: xau:Xaut_1415 dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. (457 aa)
Snov_3881KEGG: azc:AZC_0098 riboflavin kinase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (316 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (536 aa)
purDTIGRFAM: phosphoribosylamine/glycine ligase; KEGG: xau:Xaut_1412 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. (425 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (318 aa)
Snov_3944SMART: metal-dependent phosphohydrolase HD region; KEGG: xau:Xaut_1475 metal dependent phosphohydrolase. (223 aa)
Snov_3975RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: rsk:RSKD131_3273 transcriptional regulator, fis family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; Belongs to the sigma-70 factor family. ECF subfamily. (189 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (242 aa)
queGDomain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (388 aa)
Snov_4037PFAM: protein of unknown function DUF344; KEGG: mes:Meso_0013 hypothetical protein. (321 aa)
Snov_4180Dihydropyrimidinase; KEGG: mes:Meso_2664 phenylhydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. (485 aa)
Snov_4211KEGG: rhi:NGR_b13630 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (321 aa)
Snov_4237PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: bja:blr3350 carbon monoxide dehydrogenase large chain. (780 aa)
Snov_4266Dihydropyrimidinase; KEGG: mno:Mnod_7926 dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase. (475 aa)
Snov_4268PFAM: NAD-dependent epimerase/dehydratase; KEGG: mno:Mnod_8560 NAD-dependent epimerase/dehydratase. (309 aa)
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1140 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (254 aa)
atpEH+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa)
atpFH+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (204 aa)
atpF-2H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (160 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (658 aa)
Snov_4502SMART: DNA polymerase III beta chain; TIGRFAM: DNA polymerase III, beta subunit; KEGG: mrd:Mrad2831_2239 DNA polymerase III subunit beta; PFAM: DNA polymerase III beta chain. (406 aa)
apaGPFAM: ApaG domain protein; KEGG: azc:AZC_4024 ApaG. (130 aa)
Snov_0053RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: nwi:Nwi_2773 RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
Snov_0065Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (363 aa)
Snov_0068PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: azc:AZC_0393 putative ATP dependent DNA ligase. (568 aa)
Snov_0083dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (193 aa)
Snov_0085dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (297 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (221 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
Snov_0296Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (409 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (161 aa)
Snov_0352RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (532 aa)
Snov_0396PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: azc:AZC_1400 putative oxidoreductase. (736 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (356 aa)
Snov_0491L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (502 aa)
Snov_0492TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: mex:Mext_2646 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (285 aa)
Snov_0558TIGRFAM: nucleotide sugar dehydrogenase; KEGG: oan:Oant_4414 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (463 aa)
Snov_0561PFAM: NAD-dependent epimerase/dehydratase; KEGG: hne:HNE_2698 NAD-dependent epimerase/dehydratase family protein. (336 aa)
Snov_0577DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (371 aa)
Snov_0599KEGG: azc:AZC_2243 acetoacetyl-CoA synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase. (655 aa)
Snov_0687TIGRFAM: deoxycytidine triphosphate deaminase; KEGG: rpc:RPC_1525 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase. (185 aa)
Snov_0819DNA ligase D; KEGG: rhi:NGR_b04710 putative ATP-dependent DNA ligase; TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, polymerase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit. (842 aa)
Snov_0825Nicotinamidase; KEGG: bja:bll4549 pyrazinamidase/nicotinamidase; PFAM: isochorismatase hydrolase. (218 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (557 aa)
Snov_0921KEGG: hha:Hhal_1150 hypothetical protein. (396 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (496 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (533 aa)
Snov_0992RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: bja:bll6484 ECF sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein. (188 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (499 aa)
Snov_1078Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (494 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (220 aa)
Snov_1098PFAM: DNA polymerase III chi subunit HolC; KEGG: azc:AZC_0540 DNA polymerase III chi subunit. (148 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (217 aa)
purMTIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: azc:AZC_4161 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (359 aa)
Snov_1186TIGRFAM: ribose-phosphate pyrophosphokinase; KEGG: bja:bll3116 phosphoribosylpyrophosphate synthetase; PFAM: phosphoribosyltransferase. (301 aa)
Snov_1191TIGRFAM: ribose-phosphate pyrophosphokinase; KEGG: pzu:PHZ_c0646 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (340 aa)
Snov_1209TIGRFAM: malonate decarboxylase, beta subunit; KEGG: mrd:Mrad2831_0169 malonate decarboxylase subunit beta. (309 aa)
Snov_1324acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (176 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1376 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1396 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (338 aa)
dinBDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (457 aa)
pyrCDihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (432 aa)
pyrBTIGRFAM: aspartate carbamoyltransferase; KEGG: azc:AZC_2851 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa)
Snov_1535PFAM: protein of unknown function DUF344; KEGG: xau:Xaut_2307 hypothetical protein. (276 aa)
Snov_1560PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: sme:SM_b20132 putative dehydrogenase. (789 aa)
Snov_1562PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: met:M446_0552 molybdopterin dehydrogenase FAD-binding. (281 aa)
Snov_1612KEGG: gbr:Gbro_4379 protein of unknown function DUF201. (299 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (129 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (197 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (160 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa)
queAS-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (364 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (382 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (243 aa)
Snov_1771KEGG: azc:AZC_2174 putative DNA polymerase III delta prime subunit. (344 aa)
Snov_1787PFAM: CinA domain protein; KEGG: azc:AZC_3090 CinA protein; Belongs to the CinA family. (171 aa)
Snov_1793Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (472 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (153 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (450 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)
Snov_1840TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: xau:Xaut_4284 DNA polymerase III subunit alpha; SMART: phosphoesterase PHP domain protein. (1149 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (494 aa)
Snov_1936KEGG: dar:Daro_2209 hypothetical protein. (461 aa)
Snov_1972KEGG: nmu:Nmul_A0535 hypothetical protein. (457 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (168 aa)
Snov_2084PFAM: molybdopterin binding domain; KEGG: azc:AZC_1819 competence-damage associated protein. (247 aa)
Snov_2143KEGG: nwi:Nwi_2167 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa)
purCTIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: azc:AZC_2228 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (269 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (232 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (737 aa)
Snov_2151PFAM: BolA family protein; KEGG: oca:OCAR_5454 BolA family protein; Belongs to the BolA/IbaG family. (77 aa)
Snov_2168Putative RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: rpe:RPE_4735 RNA polymerase ECF-subfamily sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2. (411 aa)
Snov_2178KEGG: cak:Caul_0759 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein. (181 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (430 aa)
rpoDRNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (666 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (645 aa)
carAKEGG: xau:Xaut_1243 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (400 aa)
carBKEGG: azc:AZC_1145 carbamoyl-phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. (1111 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
rpoHRNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (303 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
Snov_2799PFAM: BolA family protein; KEGG: azc:AZC_3676 hypothetical protein; Belongs to the BolA/IbaG family. (97 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
purHSMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: xau:Xaut_1732 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein. (529 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
Snov_3078PFAM: protein of unknown function DUF179; KEGG: xau:Xaut_2594 hypothetical protein; Belongs to the UPF0301 (AlgH) family. (208 aa)
Snov_3083PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_0943 putative propionate--CoA ligase. (641 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (168 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (363 aa)
Snov_3206PFAM: NAD-dependent epimerase/dehydratase; KEGG: rsq:Rsph17025_4099 hypothetical protein. (339 aa)
Snov_3210PFAM: NAD-dependent epimerase/dehydratase; KEGG: kse:Ksed_18630 nucleoside-diphosphate-sugar epimerase. (379 aa)
Snov_3266KEGG: xau:Xaut_2674 ECF subfamily RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein. (172 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (729 aa)
Snov_3337TIGRFAM: nucleotide sugar dehydrogenase; KEGG: azc:AZC_2260 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (438 aa)
Snov_3386PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; [2Fe-2S]-binding domain protein; ferredoxin; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: mno:Mnod_4657 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding. (904 aa)
Snov_3407TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: azc:AZC_4610 hypoxanthine phosphoribosyl transferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (201 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (221 aa)
Snov_3457PFAM: NAD-dependent epimerase/dehydratase; KEGG: gvi:glr1439 hypothetical protein. (298 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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