STRINGSTRING
pyrH pyrH lpxD lpxD fabZ fabZ Snov_1828 Snov_1828 Snov_1827 Snov_1827 Snov_1826 Snov_1826 tpiA tpiA pyrG pyrG Snov_1809 Snov_1809 glmU glmU glmS glmS queF queF eno eno Snov_1793 Snov_1793 Snov_1792 Snov_1792 ispDF ispDF Snov_1775 Snov_1775 tmk tmk Snov_1769 Snov_1769 rlpA-2 rlpA-2 Snov_1760 Snov_1760 Snov_1756 Snov_1756 Snov_1718 Snov_1718 tgt tgt queA queA coaD coaD Snov_1672 Snov_1672 rlpA rlpA pyrE pyrE Snov_1630 Snov_1630 Snov_1622 Snov_1622 Snov_1616 Snov_1616 Snov_1612 Snov_1612 Snov_1562 Snov_1562 Snov_1560 Snov_1560 Snov_1557 Snov_1557 Snov_1535 Snov_1535 pyrB pyrB Snov_1493 Snov_1493 Snov_1483 Snov_1483 adk adk Snov_1407 Snov_1407 Snov_1395 Snov_1395 anmK anmK Snov_1334 Snov_1334 Snov_1333 Snov_1333 Snov_1324 Snov_1324 Snov_1239 Snov_1239 Snov_1209 Snov_1209 Snov_1203 Snov_1203 Snov_1191 Snov_1191 Snov_1187 Snov_1187 Snov_1186 Snov_1186 Snov_1138 Snov_1138 Snov_1137 Snov_1137 Snov_1135 Snov_1135 Snov_1134 Snov_1134 Snov_1133 Snov_1133 purM purM purN purN ndk ndk gmk gmk mltG mltG purF purF Snov_1066 Snov_1066 guaA guaA guaB guaB Snov_0944 Snov_0944 Snov_0942 Snov_0942 Snov_0941 Snov_0941 Snov_0937 Snov_0937 rpiA rpiA Snov_0895 Snov_0895 Snov_0839 Snov_0839 Snov_0687 Snov_0687 Snov_0599 Snov_0599 Snov_0567 Snov_0567 Snov_0561 Snov_0561 Snov_0559 Snov_0559 Snov_0558 Snov_0558 Snov_0505 Snov_0505 purU purU Snov_0431 Snov_0431 Snov_0426 Snov_0426 Snov_0396 Snov_0396 Snov_0374 Snov_0374 Snov_0342 Snov_0342 gpmA gpmA uppP uppP dut dut Snov_0296 Snov_0296 Snov_0291 Snov_0291 Snov_0273 Snov_0273 Snov_0264 Snov_0264 Snov_0260 Snov_0260 kdsB kdsB Snov_0211 Snov_0211 murA murA upp upp Snov_0085 Snov_0085 Snov_0084 Snov_0084 Snov_0083 Snov_0083 Snov_0065 Snov_0065 Snov_0677 Snov_0677 lpxK lpxK pyrF pyrF Snov_4029 Snov_4029 queG queG Snov_4032 Snov_4032 Snov_4037 Snov_4037 Snov_4211 Snov_4211 fbiD fbiD Snov_4233 Snov_4233 Snov_4237 Snov_4237 Snov_4268 Snov_4268 Snov_4286 Snov_4286 Snov_4298 Snov_4298 Snov_4403 Snov_4403 Snov_4415 Snov_4415 Snov_4421 Snov_4421 atpB atpB atpE atpE atpF atpF atpF-2 atpF-2 dxs dxs Snov_4485 Snov_4485 Snov_4497 Snov_4497 accA accA gpsA gpsA Snov_2810 Snov_2810 acsA acsA purH purH Snov_2816 Snov_2816 Snov_2818 Snov_2818 ispG ispG purA purA Snov_3025 Snov_3025 Snov_3026 Snov_3026 Snov_3069 Snov_3069 pgk pgk Snov_3072 Snov_3072 Snov_3078 Snov_3078 Snov_3083 Snov_3083 ispH ispH thyA thyA Snov_3112 Snov_3112 Snov_3113 Snov_3113 purE purE purK purK lpxC lpxC ddl ddl murB murB murC murC murG murG murD murD mraY mraY murF murF murE murE Snov_3155 Snov_3155 Snov_3156 Snov_3156 Snov_3164 Snov_3164 Snov_3165 Snov_3165 Snov_3168 Snov_3168 Snov_3170 Snov_3170 Snov_3205 Snov_3205 Snov_3206 Snov_3206 Snov_3208 Snov_3208 Snov_3209 Snov_3209 Snov_3210 Snov_3210 Snov_3211 Snov_3211 Snov_3216 Snov_3216 Snov_3217 Snov_3217 Snov_3218 Snov_3218 Snov_3219 Snov_3219 Snov_3221 Snov_3221 Snov_3225 Snov_3225 Snov_3256 Snov_3256 Snov_3276 Snov_3276 Snov_3291 Snov_3291 Snov_3300 Snov_3300 Snov_3301 Snov_3301 Snov_3337 Snov_3337 glpK glpK Snov_3386 Snov_3386 zwf zwf pgl pgl Snov_3404 Snov_3404 Snov_3407 Snov_3407 Snov_3417 Snov_3417 rppH rppH Snov_3457 Snov_3457 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH Snov_3494 Snov_3494 Snov_3497 Snov_3497 Snov_3631 Snov_3631 Snov_3704 Snov_3704 Snov_3716 Snov_3716 Snov_3734 Snov_3734 Snov_3736 Snov_3736 Snov_3740 Snov_3740 Snov_3743 Snov_3743 Snov_3765 Snov_3765 gmd gmd Snov_3774 Snov_3774 Snov_3783 Snov_3783 Snov_3785 Snov_3785 Snov_3796 Snov_3796 coaE coaE Snov_3819 Snov_3819 coaA coaA zwf-2 zwf-2 Snov_3857 Snov_3857 Snov_3881 Snov_3881 ispE ispE purD purD Snov_3922 Snov_3922 accD accD Snov_3931 Snov_3931 Snov_3944 Snov_3944 Snov_3947 Snov_3947 Snov_3970 Snov_3970 tal tal Snov_3998 Snov_3998 Snov_2792 Snov_2792 Snov_2767 Snov_2767 mtgA mtgA Snov_2717 Snov_2717 Snov_2539 Snov_2539 phnN phnN prs prs Snov_2361 Snov_2361 carB carB carA carA Snov_2325 Snov_2325 Snov_2298 Snov_2298 Snov_2266 Snov_2266 murJ murJ Snov_2255 Snov_2255 pgi pgi Snov_2241 Snov_2241 Snov_2237 Snov_2237 ackA ackA Snov_2159 Snov_2159 murI murI purL purL purQ purQ purS purS purC purC Snov_2143 Snov_2143 Snov_2141 Snov_2141 Snov_2111 Snov_2111 gpt gpt Snov_1936 Snov_1936 Snov_1911 Snov_1911 Snov_1893 Snov_1893 Snov_1891 Snov_1891 surE surE kdsA kdsA Snov_1870 Snov_1870
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (354 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (166 aa)
Snov_1828acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (275 aa)
Snov_1827PFAM: protein of unknown function DUF1009; KEGG: xau:Xaut_4427 hypothetical protein. (297 aa)
Snov_1826lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (396 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa)
Snov_1809KEGG: azc:AZC_3066 hypothetical protein. (289 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (450 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (153 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
Snov_1793Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (472 aa)
Snov_1792Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (458 aa)
ispDF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (402 aa)
Snov_1775KEGG: xau:Xaut_4391 MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. (277 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (243 aa)
Snov_1769KEGG: mrd:Mrad2831_1507 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; Belongs to the peptidase S11 family. (414 aa)
rlpA-2Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (357 aa)
Snov_1760PFAM: glycosyl transferase group 1; KEGG: rpc:RPC_4195 glycosyl transferase, group 1. (815 aa)
Snov_1756PFAM: sulfatase; KEGG: mrd:Mrad2831_0949 sulfatase. (529 aa)
Snov_1718PFAM: Lytic transglycosylase catalytic; KEGG: oan:Oant_0077 lytic transglycosylase catalytic. (183 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (382 aa)
queAS-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (364 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa)
Snov_1672PFAM: lipopolysaccharide biosynthesis protein; KEGG: azc:AZC_2186 putative ATPase. (492 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (173 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (197 aa)
Snov_1630(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (733 aa)
Snov_1622PFAM: Lytic transglycosylase catalytic; Tetratricopeptide TPR_4; KEGG: xau:Xaut_3828 lytic transglycosylase catalytic. (720 aa)
Snov_1616TIGRFAM: succinate CoA transferase; KEGG: azc:AZC_3728 acetyl-CoA hydrolase; PFAM: acetyl-CoA hydrolase/transferase. (497 aa)
Snov_1612KEGG: gbr:Gbro_4379 protein of unknown function DUF201. (299 aa)
Snov_1562PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: met:M446_0552 molybdopterin dehydrogenase FAD-binding. (281 aa)
Snov_1560PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: sme:SM_b20132 putative dehydrogenase. (789 aa)
Snov_1557KEGG: mes:Meso_4116 hypothetical protein. (339 aa)
Snov_1535PFAM: protein of unknown function DUF344; KEGG: xau:Xaut_2307 hypothetical protein. (276 aa)
pyrBTIGRFAM: aspartate carbamoyltransferase; KEGG: azc:AZC_2851 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa)
Snov_1493KEGG: xau:Xaut_4539 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Sporulation domain protein; Belongs to the peptidase S11 family. (570 aa)
Snov_1483PFAM: protein of unknown function DUF218; KEGG: xau:Xaut_4460 hypothetical protein. (274 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa)
Snov_1407PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mpo:Mpop_0378 ErfK/YbiS/YcfS/YnhG family protein. (233 aa)
Snov_1395KEGG: xau:Xaut_4551 glycosyl transferase family protein. (590 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (384 aa)
Snov_1334KEGG: azc:AZC_3625 penicillin-binding protein 1A precursor; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase. (812 aa)
Snov_1333N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: xau:Xaut_4667 N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin. (435 aa)
Snov_1324acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
Snov_1239PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: xau:Xaut_1072 ErfK/YbiS/YcfS/YnhG family protein. (225 aa)
Snov_1209TIGRFAM: malonate decarboxylase, beta subunit; KEGG: mrd:Mrad2831_0169 malonate decarboxylase subunit beta. (309 aa)
Snov_1203KEGG: dal:Dalk_2059 GCN5-related N-acetyltransferase. (377 aa)
Snov_1191TIGRFAM: ribose-phosphate pyrophosphokinase; KEGG: pzu:PHZ_c0646 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (340 aa)
Snov_1187TIGRFAM: thymidine phosphorylase; KEGG: rpc:RPC_4089 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like. (514 aa)
Snov_1186TIGRFAM: ribose-phosphate pyrophosphokinase; KEGG: bja:bll3116 phosphoribosylpyrophosphate synthetase; PFAM: phosphoribosyltransferase. (301 aa)
Snov_1138O-linked N-acetylglucosamine transferase SPINDLY family-like protein; KEGG: ote:Oter_3958 TPR repeat-containing protein. (1179 aa)
Snov_1137PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: acr:Acry_0289 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (377 aa)
Snov_1135PFAM: glycosyl transferase group 1; KEGG: acr:Acry_0291 glycosyl transferase, group 1. (343 aa)
Snov_1134PFAM: glycosyl transferase group 1; KEGG: acr:Acry_0292 glycosyl transferase, group 1. (350 aa)
Snov_1133TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; KEGG: ccs:CCNA_01063 putative UDP-perosamine 4-acetyl transferase. (210 aa)
purMTIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: azc:AZC_4161 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (359 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (217 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (220 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (379 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (499 aa)
Snov_1066PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: xau:Xaut_1444 ErfK/YbiS/YcfS/YnhG family protein. (222 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (533 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (496 aa)
Snov_0944KEGG: xau:Xaut_3260 penicillin-binding protein 1C; TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein. (701 aa)
Snov_0942PFAM: phosphopantetheine-binding; KEGG: azc:AZC_2403 acyl carrier protein. (93 aa)
Snov_0941PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: bbt:BBta_3521 putative 3-hydroxymyristoyl-acyl carrier protein dehydratase FabZ-like protein. (171 aa)
Snov_0937PFAM: lipid A biosynthesis acyltransferase; KEGG: mno:Mnod_1861 lipid A biosynthesis acyltransferase. (342 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (234 aa)
Snov_0895PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: bja:blr7232 hypothetical protein. (191 aa)
Snov_0839FGGY-family pentulose kinase; KEGG: bbt:BBta_0920 putative sugar kinase (ribulo-/ribitol kinase); TIGRFAM: FGGY-family pentulose kinase; PFAM: Carbohydrate kinase, FGGY-like. (547 aa)
Snov_0687TIGRFAM: deoxycytidine triphosphate deaminase; KEGG: rpc:RPC_1525 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase. (185 aa)
Snov_0599KEGG: azc:AZC_2243 acetoacetyl-CoA synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase. (655 aa)
Snov_0567KEGG: azc:AZC_0377 putative glycosyltransferase. (641 aa)
Snov_0561PFAM: NAD-dependent epimerase/dehydratase; KEGG: hne:HNE_2698 NAD-dependent epimerase/dehydratase family protein. (336 aa)
Snov_0559PFAM: glycosyl transferase family 2; KEGG: smd:Smed_3671 putative cellulose synthase protein. (647 aa)
Snov_0558TIGRFAM: nucleotide sugar dehydrogenase; KEGG: oan:Oant_4414 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (463 aa)
Snov_0505PFAM: FAD dependent oxidoreductase; KEGG: met:M446_1975 glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (516 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
Snov_0431TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: azc:AZC_1810 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
Snov_0426Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (674 aa)
Snov_0396PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: azc:AZC_1400 putative oxidoreductase. (736 aa)
Snov_0374KEGG: bja:bll0499 citrate lyase beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (297 aa)
Snov_0342PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mdi:METDI0732 hypothetical protein. (225 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa)
uppPUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (161 aa)
Snov_0296Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (409 aa)
Snov_0291PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rpb:RPB_1841 ErfK/YbiS/YcfS/YnhG. (332 aa)
Snov_0273PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: azc:AZC_1194 ErfK/YbiS/YcfS/YnhG precursor. (200 aa)
Snov_0264PFAM: Phosphoglycerate mutase; KEGG: xau:Xaut_4141 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (196 aa)
Snov_0260PFAM: NUDIX hydrolase; KEGG: xau:Xaut_2637 NUDIX hydrolase. (215 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
Snov_0211PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: glyoxalase/bleomycin resistance protein/dioxygenase. (159 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (429 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (221 aa)
Snov_0085dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (297 aa)
Snov_0084KEGG: azc:AZC_1833 dTDP-D-glucose-4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa)
Snov_0083dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (193 aa)
Snov_0065Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (363 aa)
Snov_0677KEGG: xau:Xaut_1653 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase. (749 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (335 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (242 aa)
Snov_4029PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: xau:Xaut_0348 glyoxalase/bleomycin resistance protein/dioxygenase. (128 aa)
queGDomain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (388 aa)
Snov_4032PFAM: NAD-dependent epimerase/dehydratase; KEGG: azc:AZC_4677 putative NAD-dependent epimerase. (296 aa)
Snov_4037PFAM: protein of unknown function DUF344; KEGG: mes:Meso_0013 hypothetical protein. (321 aa)
Snov_4211KEGG: rhi:NGR_b13630 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (321 aa)
fbiD2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (232 aa)
Snov_4233KEGG: oca:OCAR_5004 putative F420-dependent oxidoreductase; TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129. (260 aa)
Snov_4237PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: bja:blr3350 carbon monoxide dehydrogenase large chain. (780 aa)
Snov_4268PFAM: NAD-dependent epimerase/dehydratase; KEGG: mno:Mnod_8560 NAD-dependent epimerase/dehydratase. (309 aa)
Snov_4286KEGG: bte:BTH_II2235 citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (301 aa)
Snov_4298PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: dfe:Dfer_3264 glucosamine/galactosamine-6-phosphate isomerase. (254 aa)
Snov_4403KEGG: azo:azo0750 hypothetical protein. (585 aa)
Snov_4415PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: azc:AZC_0244 dioxygenase. (310 aa)
Snov_4421PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: xau:Xaut_1945 glyoxalase/bleomycin resistance protein/dioxygenase. (180 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (254 aa)
atpEH+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa)
atpFH+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (204 aa)
atpF-2H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (160 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa)
Snov_4485PFAM: 2-deoxycytidine 5-triphosphate deaminase; KEGG: azc:AZC_4020 2'-deoxycytidine 5'-triphosphate deaminase. (372 aa)
Snov_4497KEGG: xau:Xaut_0362 1A family penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase. (722 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
gpsAKEGG: azc:AZC_0263 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (329 aa)
Snov_2810Lysozyme; KEGG: mar:MAE_60270 lysozyme; PFAM: glycoside hydrolase family 24; Peptidoglycan-binding domain 1 protein; ErfK/YbiS/YcfS/YnhG family protein. (508 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
purHSMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: xau:Xaut_1732 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein. (529 aa)
Snov_2816PFAM: Heparinase II/III family protein; KEGG: azc:AZC_4697 hypothetical protein. (576 aa)
Snov_2818Glucokinase; KEGG: xau:Xaut_2047 glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (323 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (429 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
Snov_3025PFAM: glycosyl transferase family 39; KEGG: rce:RC1_1920 glycosyl transferase, family 39. (568 aa)
Snov_3026PFAM: lipid A biosynthesis domain protein; KEGG: nwi:Nwi_1531 lipid A biosynthesis. (114 aa)
Snov_3069Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
pgkKEGG: azc:AZC_0502 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
Snov_3072KEGG: xau:Xaut_3077 fructose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I. (340 aa)
Snov_3078PFAM: protein of unknown function DUF179; KEGG: xau:Xaut_2594 hypothetical protein; Belongs to the UPF0301 (AlgH) family. (208 aa)
Snov_3083PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_0943 putative propionate--CoA ligase. (641 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (323 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
Snov_3112PFAM: protein of unknown function DUF882; KEGG: azc:AZC_0440 hypothetical protein. (549 aa)
Snov_3113PFAM: ErfK/YbiS/YcfS/YnhG family protein; Peptidoglycan-binding domain 1 protein; KEGG: xau:Xaut_2068 peptidoglycan binding domain-containing protein. (678 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (168 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (363 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (312 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (306 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (306 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (469 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (370 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (460 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (479 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
Snov_3155N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; Peptidoglycan-binding domain 1 protein; KEGG: azc:AZC_4549 N-acetylmuramoyl-L-alanine amidase; SMART: N-acetylmuramoyl-L-alanine amidase family 2. (280 aa)
Snov_3156PFAM: Lytic transglycosylase catalytic; KEGG: oan:Oant_1733 lytic transglycosylase catalytic. (175 aa)
Snov_3164TIGRFAM: pyruvate kinase; KEGG: azc:AZC_3491 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (516 aa)
Snov_3165PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mno:Mnod_5216 ErfK/YbiS/YcfS/YnhG family protein. (170 aa)
Snov_3168PFAM: acyltransferase 3; KEGG: rsp:RSP_4209 acyltransferase. (380 aa)
Snov_3170KEGG: rlt:Rleg2_1204 cellulose synthase catalytic subunit (UDP-forming); TIGRFAM: cellulose synthase catalytic subunit (UDP-forming); PFAM: glycosyl transferase family 2; type IV pilus assembly PilZ. (735 aa)
Snov_3205Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (791 aa)
Snov_3206PFAM: NAD-dependent epimerase/dehydratase; KEGG: rsq:Rsph17025_4099 hypothetical protein. (339 aa)
Snov_3208PFAM: glycosyl transferase group 1; KEGG: ajs:Ajs_3033 glycosyl transferase, group 1. (422 aa)
Snov_3209TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: kse:Ksed_18640 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (377 aa)
Snov_3210PFAM: NAD-dependent epimerase/dehydratase; KEGG: kse:Ksed_18630 nucleoside-diphosphate-sugar epimerase. (379 aa)
Snov_3211UDP-glucose 4-epimerase; KEGG: pfl:PFL_5106 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; Polysaccharide biosynthesis domain protein. (341 aa)
Snov_3216PFAM: polysaccharide biosynthesis protein; KEGG: eba:ebA5876 flippase Wzx. (441 aa)
Snov_3217PFAM: polysaccharide biosynthesis protein CapD; KEGG: swp:swp_1595 polysaccharide biosynthesis protein CapD. (664 aa)
Snov_3218KEGG: tmz:Tmz1t_1130 glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (399 aa)
Snov_3219TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; KEGG: avn:Avin_30060 trimeric LpxA-like family protein. (214 aa)
Snov_3221Hypothetical protein; KEGG: hba:Hbal_1797 O-antigen polymerase. (478 aa)
Snov_3225TIGRFAM: capsular exopolysaccharide family; KEGG: eba:ebA6797 exopolysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein. (777 aa)
Snov_3256PFAM: NAD-dependent epimerase/dehydratase; KEGG: mrd:Mrad2831_3413 NAD-dependent epimerase/dehydratase. (289 aa)
Snov_3276KEGG: azc:AZC_3736 citrate lyase beta subunit; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (299 aa)
Snov_3291KEGG: azc:AZC_1002 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Belongs to the peptidase S11 family. (461 aa)
Snov_3300TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: xau:Xaut_0156 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component. (992 aa)
Snov_33012-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
Snov_3337TIGRFAM: nucleotide sugar dehydrogenase; KEGG: azc:AZC_2260 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (438 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (498 aa)
Snov_3386PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; [2Fe-2S]-binding domain protein; ferredoxin; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: mno:Mnod_4657 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding. (904 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (227 aa)
Snov_3404PFAM: protein of unknown function DUF218; KEGG: xau:Xaut_0020 hypothetical protein. (228 aa)
Snov_3407TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: azc:AZC_4610 hypoxanthine phosphoribosyl transferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (201 aa)
Snov_3417PFAM: acyl-CoA thioesterase; KEGG: mno:Mnod_1819 acyl-CoA thioesterase II. (295 aa)
rppHNUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (185 aa)
Snov_3457PFAM: NAD-dependent epimerase/dehydratase; KEGG: gvi:glr1439 hypothetical protein. (298 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (477 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (184 aa)
Snov_3494PFAM: NAD-dependent epimerase/dehydratase; KEGG: bbt:BBta_5514 putative dihydrokaempferol 4-reductase (NAD-dependent epimerase/dehydratase). (341 aa)
Snov_3497PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mrd:Mrad2831_1356 putative circadian phase modifier CpmA-like protein. (220 aa)
Snov_3631KEGG: mno:Mnod_7300 hypothetical protein. (119 aa)
Snov_3704Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (205 aa)
Snov_3716PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: azc:AZC_0069 putative selenophosphate synthetase-related protein. (332 aa)
Snov_3734KEGG: met:M446_4784 hypothetical protein. (133 aa)
Snov_3736PFAM: Methyltransferase type 12; KEGG: mno:Mnod_4661 hypothetical protein. (277 aa)
Snov_3740PFAM: NUDIX hydrolase; KEGG: mjl:Mjls_2909 NUDIX hydrolase. (153 aa)
Snov_3743PFAM: protein of unknown function DUF344; KEGG: gbe:GbCGDNIH1_1622 polyphosphate kinase. (306 aa)
Snov_3765PFAM: glycosyl transferase family 2; KEGG: hne:HNE_0801 glycosyl transferase, group 2 family protein. (312 aa)
gmdNAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (338 aa)
Snov_3774PFAM: glycosyl transferase group 1; KEGG: jan:Jann_4279 glycosyl transferase, group 1. (410 aa)
Snov_3783KEGG: swi:Swit_4009 glycosyl transferase, group 1. (653 aa)
Snov_3785PFAM: glycosyl transferase group 1; KEGG: reu:Reut_A0718 glycosyl transferase family protein. (483 aa)
Snov_3796PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: azc:AZC_0089 hypothetical protein. (199 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (207 aa)
Snov_3819PFAM: MltA domain protein; 3D domain protein; KEGG: xau:Xaut_2049 MltA domain-containing protein. (416 aa)
coaATIGRFAM: pantothenate kinase; KEGG: azc:AZC_4496 pantothenate kinase. (320 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (513 aa)
Snov_38576-phosphogluconate dehydrogenase, decarboxylating; KEGG: bid:Bind_0459 6-phosphogluconate dehydrogenase-like protein; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein. (326 aa)
Snov_3881KEGG: azc:AZC_0098 riboflavin kinase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (316 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (296 aa)
purDTIGRFAM: phosphoribosylamine/glycine ligase; KEGG: xau:Xaut_1412 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. (425 aa)
Snov_3922TIGRFAM: FolC bifunctional protein; KEGG: azc:AZC_1025 folylpolyglutamate synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein. (447 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (318 aa)
Snov_3931KEGG: azc:AZC_3715 hypothetical protein. (126 aa)
Snov_3944SMART: metal-dependent phosphohydrolase HD region; KEGG: xau:Xaut_1475 metal dependent phosphohydrolase. (223 aa)
Snov_3947PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rhi:NGR_c08420 hypothetical protein. (225 aa)
Snov_3970PFAM: virulence factor MVIN family protein; KEGG: xau:Xaut_3084 integral membrane protein MviN. (505 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (323 aa)
Snov_3998Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (431 aa)
Snov_2792KEGG: xau:Xaut_0510 hypothetical protein. (593 aa)
Snov_2767KEGG: avi:Avi_5923 pyruvate kinase; PFAM: Pyruvate kinase barrel; Belongs to the pyruvate kinase family. (501 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (222 aa)
Snov_2717TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: xau:Xaut_0389 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. (296 aa)
Snov_2539PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: xau:Xaut_1639 ErfK/YbiS/YcfS/YnhG family protein. (210 aa)
phnNPhosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (203 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
Snov_2361PFAM: glycosyl transferase family 8; KEGG: bay:RBAM_035670 GspA. (299 aa)
carBKEGG: azc:AZC_1145 carbamoyl-phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; Belongs to the CarB family. (1111 aa)
carAKEGG: xau:Xaut_1243 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (400 aa)
Snov_2325PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rpt:Rpal_4131 ErfK/YbiS/YcfS/YnhG family protein. (401 aa)
Snov_2298PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: azc:AZC_4327 hypothetical protein. (336 aa)
Snov_2266PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: azc:AZC_3959 aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (384 aa)
murJIntegral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (516 aa)
Snov_2255PFAM: MltA-interacting MipA family protein; KEGG: azc:AZC_1663 hypothetical protein. (286 aa)
pgiKEGG: bov:BOV_0299 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family. (547 aa)
Snov_2241PFAM: lipopolysaccharide biosynthesis protein; KEGG: azc:AZC_4423 hypothetical protein. (705 aa)
Snov_2237KEGG: azc:AZC_4421 glycosyltransferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; Belongs to the glycosyltransferase 26 family. (278 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
Snov_2159KEGG: azc:AZC_1866 hypothetical protein. (278 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (280 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (737 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (232 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa)
purCTIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: azc:AZC_2228 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (269 aa)
Snov_2143KEGG: nwi:Nwi_2167 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa)
Snov_2141TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: bra:BRADO2842 ribulose-phosphate 3-epimerase (pentose-5-phosphate 3-epimerase) (PPE) (R5P3E); PFAM: ribulose-phosphate 3-epimerase. (228 aa)
Snov_2111PFAM: metallophosphoesterase; KEGG: azc:AZC_2301 hypothetical protein. (269 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (168 aa)
Snov_1936KEGG: dar:Daro_2209 hypothetical protein. (461 aa)
Snov_1911PFAM: NAD-dependent epimerase/dehydratase; KEGG: cak:Caul_1797 NAD-dependent epimerase/dehydratase. (269 aa)
Snov_1893MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (249 aa)
Snov_1891TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: azc:AZC_2807 deoxyguanosinetriphosphate; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily. (390 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (254 aa)
kdsAKEGG: xau:Xaut_4203 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. (286 aa)
Snov_1870TIGRFAM: KpsF/GutQ family protein; KEGG: mno:Mnod_1252 KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein; Belongs to the SIS family. GutQ/KpsF subfamily. (338 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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