STRINGSTRING
Snov_3026 Snov_3026 lpxC lpxC Snov_3168 Snov_3168 Snov_3211 Snov_3211 Snov_3216 Snov_3216 Snov_3217 Snov_3217 Snov_3218 Snov_3218 Snov_3219 Snov_3219 Snov_3225 Snov_3225 Snov_3765 Snov_3765 Snov_3998 Snov_3998 Snov_3931 Snov_3931 Snov_4403 Snov_4403 kdsB kdsB Snov_0937 Snov_0937 Snov_0941 Snov_0941 Snov_0942 Snov_0942 Snov_1133 Snov_1133 Snov_1137 Snov_1137 Snov_1672 Snov_1672 Snov_1756 Snov_1756 glmU glmU Snov_1826 Snov_1826 Snov_1827 Snov_1827 Snov_1828 Snov_1828 fabZ fabZ lpxD lpxD kdsA kdsA Snov_2111 Snov_2111 Snov_2241 Snov_2241 Snov_2266 Snov_2266 lpxK lpxK Snov_2361 Snov_2361
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Snov_3026PFAM: lipid A biosynthesis domain protein; KEGG: nwi:Nwi_1531 lipid A biosynthesis. (114 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (312 aa)
Snov_3168PFAM: acyltransferase 3; KEGG: rsp:RSP_4209 acyltransferase. (380 aa)
Snov_3211UDP-glucose 4-epimerase; KEGG: pfl:PFL_5106 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; Polysaccharide biosynthesis domain protein. (341 aa)
Snov_3216PFAM: polysaccharide biosynthesis protein; KEGG: eba:ebA5876 flippase Wzx. (441 aa)
Snov_3217PFAM: polysaccharide biosynthesis protein CapD; KEGG: swp:swp_1595 polysaccharide biosynthesis protein CapD. (664 aa)
Snov_3218KEGG: tmz:Tmz1t_1130 glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (399 aa)
Snov_3219TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; KEGG: avn:Avin_30060 trimeric LpxA-like family protein. (214 aa)
Snov_3225TIGRFAM: capsular exopolysaccharide family; KEGG: eba:ebA6797 exopolysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein. (777 aa)
Snov_3765PFAM: glycosyl transferase family 2; KEGG: hne:HNE_0801 glycosyl transferase, group 2 family protein. (312 aa)
Snov_3998Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (431 aa)
Snov_3931KEGG: azc:AZC_3715 hypothetical protein. (126 aa)
Snov_4403KEGG: azo:azo0750 hypothetical protein. (585 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
Snov_0937PFAM: lipid A biosynthesis acyltransferase; KEGG: mno:Mnod_1861 lipid A biosynthesis acyltransferase. (342 aa)
Snov_0941PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: bbt:BBta_3521 putative 3-hydroxymyristoyl-acyl carrier protein dehydratase FabZ-like protein. (171 aa)
Snov_0942PFAM: phosphopantetheine-binding; KEGG: azc:AZC_2403 acyl carrier protein. (93 aa)
Snov_1133TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; KEGG: ccs:CCNA_01063 putative UDP-perosamine 4-acetyl transferase. (210 aa)
Snov_1137PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: acr:Acry_0289 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (377 aa)
Snov_1672PFAM: lipopolysaccharide biosynthesis protein; KEGG: azc:AZC_2186 putative ATPase. (492 aa)
Snov_1756PFAM: sulfatase; KEGG: mrd:Mrad2831_0949 sulfatase. (529 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (450 aa)
Snov_1826lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (396 aa)
Snov_1827PFAM: protein of unknown function DUF1009; KEGG: xau:Xaut_4427 hypothetical protein. (297 aa)
Snov_1828acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (275 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (166 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (354 aa)
kdsAKEGG: xau:Xaut_4203 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. (286 aa)
Snov_2111PFAM: metallophosphoesterase; KEGG: azc:AZC_2301 hypothetical protein. (269 aa)
Snov_2241PFAM: lipopolysaccharide biosynthesis protein; KEGG: azc:AZC_4423 hypothetical protein. (705 aa)
Snov_2266PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: azc:AZC_3959 aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (384 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (335 aa)
Snov_2361PFAM: glycosyl transferase family 8; KEGG: bay:RBAM_035670 GspA. (299 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.