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pqqE pqqE Snov_1151 Snov_1151 moaA-2 moaA-2 Snov_1553 Snov_1553 dapA dapA pdxJ pdxJ Snov_1646 Snov_1646 Snov_1785 Snov_1785 lipA lipA tpiA tpiA trpC trpC Snov_1916 Snov_1916 kdsA kdsA Snov_1921 Snov_1921 Snov_1971 Snov_1971 Snov_2125 Snov_2125 Snov_2141 Snov_2141 Snov_2271 Snov_2271 leuA leuA Snov_2429 Snov_2429 Snov_2512 Snov_2512 Snov_2522 Snov_2522 thiE thiE thiG thiG Snov_2713 Snov_2713 Snov_2718 Snov_2718 Snov_2999 Snov_2999 Snov_3021 Snov_3021 Snov_3072 Snov_3072 Snov_3075 Snov_3075 Snov_3163 Snov_3163 rlmN rlmN Snov_4230 Snov_4230 Snov_4074 Snov_4074 Snov_4068 Snov_4068 pyrF pyrF tal tal trpF trpF trpA trpA Snov_3840 Snov_3840 hisF hisF hisA hisA Snov_3714 Snov_3714 Snov_3532 Snov_3532 Snov_3378 Snov_3378 Snov_0065 Snov_0065 Snov_0118 Snov_0118 Snov_0159 Snov_0159 Snov_0175 Snov_0175 Snov_0225 Snov_0225 Snov_0392 Snov_0392 Snov_0427 Snov_0427 Snov_0431 Snov_0431 Snov_0456 Snov_0456 Snov_0492 Snov_0492 Snov_0680 Snov_0680 Snov_0747 Snov_0747 dusA dusA moaA moaA Snov_0906 Snov_0906 guaB guaB
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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pqqECoenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (380 aa)
Snov_1151SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; KEGG: rde:RD1_1696 coproporphyrinogen III oxidase; PFAM: HemN domain protein; Radical SAM domain protein; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (454 aa)
moaA-2Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (348 aa)
Snov_1553KEGG: azc:AZC_3564 ethanolamine ammonia-lyase large subunit; PFAM: Ethanolamine ammonia lyase large subunit. (462 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
pdxJPyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (257 aa)
Snov_1646Porphobilinogen synthase; KEGG: xau:Xaut_4295 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (353 aa)
Snov_1785TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (343 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (325 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
trpCKEGG: azc:AZC_2205 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (270 aa)
Snov_1916PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: mrd:Mrad2831_3410 L-lactate dehydrogenase (cytochrome). (421 aa)
kdsAKEGG: xau:Xaut_4203 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. (286 aa)
Snov_1921PFAM: dihydrodipicolinate synthetase; KEGG: azc:AZC_0731 dihydrodipicolinate synthetase; Belongs to the DapA family. (314 aa)
Snov_1971PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: rle:pRL110496 putative FMN oxidoreductase. (483 aa)
Snov_2125TIGRFAM: lysine 2,3-aminomutase YodO family protein; KEGG: azc:AZC_2928 putative lysine 2,3-aminomutase; PFAM: Radical SAM domain protein. (385 aa)
Snov_2141TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: bra:BRADO2842 ribulose-phosphate 3-epimerase (pentose-5-phosphate 3-epimerase) (PPE) (R5P3E); PFAM: ribulose-phosphate 3-epimerase. (228 aa)
Snov_2271PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: xau:Xaut_1327 NADH:flavin oxidoreductase/NADH oxidase. (365 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (517 aa)
Snov_2429PFAM: protein of unknown function DUF849; KEGG: rle:RL2483 hypothetical protein. (245 aa)
Snov_2512PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: avn:Avin_12350 L-lactate dehydrogenase/FMN-dependent alpha-hydroxy acid dehydrogenase. (369 aa)
Snov_2522PFAM: dihydrodipicolinate synthetase; KEGG: mag:amb2543 dihydrodipicolinate synthase; Belongs to the DapA family. (300 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (201 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (271 aa)
Snov_2713KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein. (1576 aa)
Snov_2718PFAM: dihydrodipicolinate synthetase; KEGG: smd:Smed_4167 dihydrodipicolinate synthetase; Belongs to the DapA family. (298 aa)
Snov_2999KEGG: azc:AZC_0561 4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase. (214 aa)
Snov_3021PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mno:Mnod_3398 NADH:flavin oxidoreductase/NADH oxidase. (688 aa)
Snov_3072KEGG: xau:Xaut_3077 fructose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I. (340 aa)
Snov_3075PFAM: thiamine monophosphate synthase; KEGG: nha:Nham_3535 thiamine monophosphate synthase. (217 aa)
Snov_3163Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1154 aa)
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (409 aa)
Snov_4230TIGRFAM: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; PFAM: Radical SAM domain protein; KEGG: oca:OCAR_5007 FO synthase; SMART: Elongator protein 3/MiaB/NifB. (814 aa)
Snov_4074PFAM: KDPG and KHG aldolase; KEGG: azc:AZC_4410 2-keto-3-deoxy-6-phosphogluconate aldolase. (208 aa)
Snov_4068(S)-mandelate dehydrogenase; KEGG: pde:Pden_5045 (S)-2-hydroxy-acid oxidase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase. (396 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (242 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (323 aa)
trpFKEGG: rpb:RPB_0636 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. (236 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa)
Snov_3840Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (381 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (261 aa)
hisATIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: xau:Xaut_2290 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein. (247 aa)
Snov_3714KEGG: msl:Msil_1993 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (369 aa)
Snov_3532PFAM: pyruvate carboxyltransferase; KEGG: acr:Acry_2695 pyruvate carboxyltransferase. (307 aa)
Snov_3378L-lactate dehydrogenase (cytochrome); KEGG: sme:SMa0404 FMN-dependent dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase. (381 aa)
Snov_0065Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (363 aa)
Snov_0118PFAM: dihydrodipicolinate synthetase; KEGG: xau:Xaut_1021 dihydrodipicolinate synthetase; Belongs to the DapA family. (310 aa)
Snov_0159PFAM: dihydrodipicolinate synthetase; KEGG: mlo:mll3981 dihydrodipicolinate synthase; Belongs to the DapA family. (298 aa)
Snov_0175PFAM: dihydrodipicolinate synthetase; KEGG: bbr:BB4720 putative dihydrodipicolinate synthase; Belongs to the DapA family. (309 aa)
Snov_0225PFAM: protein of unknown function DUF849; KEGG: mlo:mll1033 hypothetical protein. (310 aa)
Snov_0392PFAM: protein of unknown function DUF849; KEGG: sme:SMc01637 hypothetical protein. (300 aa)
Snov_0427Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (361 aa)
Snov_0431TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: azc:AZC_1810 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
Snov_0456PFAM: ferredoxin-dependent glutamate synthase; KEGG: msl:Msil_2634 ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (445 aa)
Snov_0492TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: mex:Mext_2646 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (285 aa)
Snov_0680KEGG: azc:AZC_2267 L-lactate dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase. (379 aa)
Snov_0747PFAM: histidine biosynthesis protein; KEGG: xau:Xaut_3531 histidine biosynthesis protein; Belongs to the HisA/HisF family. (232 aa)
dusATIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (337 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (348 aa)
Snov_0906TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: bja:blr3778 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II. (461 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (496 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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