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Snov_1446 Snov_1446 secY secY rpoA rpoA Snov_1508 Snov_1508 Snov_1512 Snov_1512 Snov_1539 Snov_1539 Snov_1547 Snov_1547 Snov_1549 Snov_1549 Snov_1590 Snov_1590 rpoZ rpoZ Snov_1654 Snov_1654 Snov_1792 Snov_1792 Snov_1793 Snov_1793 Snov_0060 Snov_0060 Snov_0127 Snov_0127 Snov_0192 Snov_0192 Snov_0194 Snov_0194 Snov_0259 Snov_0259 Snov_0305 Snov_0305 Snov_0338 Snov_0338 Snov_0527 Snov_0527 Snov_0530 Snov_0530 Snov_3376 Snov_3376 Snov_3301 Snov_3301 Snov_3204 Snov_3204 Snov_3175 Snov_3175 Snov_3062 Snov_3062 secA secA Snov_2775 Snov_2775 Snov_2678 Snov_2678 Snov_2675 Snov_2675 Snov_2616 Snov_2616 Snov_2611 Snov_2611 Snov_2482 Snov_2482 Snov_2400 Snov_2400 Snov_2363 Snov_2363 Snov_2362 Snov_2362 Snov_2346 Snov_2346 Snov_2344 Snov_2344 Snov_2287 Snov_2287 Snov_2187 Snov_2187 Snov_2105 Snov_2105 Snov_2099 Snov_2099 Snov_2047 Snov_2047 Snov_2032 Snov_2032 Snov_1927 Snov_1927 Snov_1900 Snov_1900 secD secD secF secF Snov_1811 Snov_1811 Snov_4472 Snov_4472 Snov_4473 Snov_4473 Snov_1180 Snov_1180 Snov_1126 Snov_1126 ndk ndk Snov_0985 Snov_0985 Snov_0956 Snov_0956 Snov_0892 Snov_0892 Snov_0870 Snov_0870 ssuD ssuD Snov_0849 Snov_0849 msrA msrA Snov_0800 Snov_0800 Snov_0799 Snov_0799 Snov_0798 Snov_0798 Snov_0661 Snov_0661 Snov_4377 Snov_4377 Snov_4346 Snov_4346 Snov_4272 Snov_4272 Snov_4271 Snov_4271 Snov_4270 Snov_4270 Snov_4226 Snov_4226 Snov_4179 Snov_4179 Snov_0596 Snov_0596 Snov_4172 Snov_4172 katG katG Snov_1317 Snov_1317 Snov_4155 Snov_4155 Snov_4039 Snov_4039 Snov_4003 Snov_4003 Snov_3985 Snov_3985 Snov_3948 Snov_3948 Snov_3825 Snov_3825 Snov_3763 Snov_3763 Snov_3755 Snov_3755 Snov_3746 Snov_3746 Snov_3738 Snov_3738 Snov_3620 Snov_3620 Snov_3619 Snov_3619 Snov_3618 Snov_3618 Snov_3596 Snov_3596 Snov_3568 Snov_3568 Snov_3503 Snov_3503 Snov_3425 Snov_3425 Snov_1294 Snov_1294 Snov_1285 Snov_1285 Snov_1284 Snov_1284 Snov_1279 Snov_1279 msrA-2 msrA-2 Snov_1320 Snov_1320 Snov_1337 Snov_1337 tuf tuf secE secE rpoB rpoB rpoC rpoC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Snov_1446KEGG: xau:Xaut_3356 elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain protein. (396 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (443 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (338 aa)
Snov_1508PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_3861 major facilitator transporter. (385 aa)
Snov_1512PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_1860 putative membrane transport protein. (492 aa)
Snov_1539PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_4144 major facilitator transporter. (399 aa)
Snov_1547PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_4675 major facilitator transporter. (454 aa)
Snov_1549PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_3740 putative oxalate. (442 aa)
Snov_1590KEGG: xau:Xaut_0875 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight. (180 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (129 aa)
Snov_1654Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (370 aa)
Snov_1792Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (458 aa)
Snov_1793Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (472 aa)
Snov_0060Peroxidase; KEGG: xau:Xaut_2363 peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like. (211 aa)
Snov_0127KEGG: xau:Xaut_1233 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight. (163 aa)
Snov_0192PFAM: Carboxymuconolactone decarboxylase; KEGG: bpy:Bphyt_5467 carboxymuconolactone decarboxylase. (181 aa)
Snov_0194PFAM: Luciferase-like, subgroup; KEGG: jan:Jann_2939 luciferase-like. (366 aa)
Snov_0259KEGG: bra:BRADO1006 oligopeptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (543 aa)
Snov_0305Thioredoxin; KEGG: xau:Xaut_3301 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family. (106 aa)
Snov_0338PFAM: Luciferase-like, subgroup; KEGG: bja:blr5498 putative oxidoreductase protein. (320 aa)
Snov_0527KEGG: dma:DMR_29330 hypothetical protein. (830 aa)
Snov_0530KEGG: smd:Smed_6457 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type. (158 aa)
Snov_3376KEGG: msm:MSMEG_6734 dibenzothiophene desulfurization enzyme A. (437 aa)
Snov_33012-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (417 aa)
Snov_3204KEGG: bid:Bind_1530 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type. (156 aa)
Snov_3175PFAM: major facilitator superfamily MFS_1; KEGG: rle:pRL120167 MFS family transporter. (398 aa)
Snov_3062TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter related; ABC transporter transmembrane region; KEGG: azc:AZC_0494 ABC transporter; SMART: AAA ATPase. (599 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (931 aa)
Snov_2775PFAM: major facilitator superfamily MFS_1; KEGG: bcm:Bcenmc03_6286 major facilitator transporter. (515 aa)
Snov_2678PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr0691 hypothetical protein. (524 aa)
Snov_2675Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (148 aa)
Snov_2616KEGG: rsh:Rsph17029_1870 EmrB/QacA family drug resistance transporter; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1. (520 aa)
Snov_2611KEGG: cak:Caul_4899 Bcr/CflA subfamily drug resistance transporter; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1. (417 aa)
Snov_2482ABC transporter related protein; KEGG: pau:PA14_22440 putative ATP-binding/permease fusion ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase. (619 aa)
Snov_2400PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: oca:OCAR_6856 alcohol dehydrogenase class 3. (370 aa)
Snov_2363KEGG: xau:Xaut_2753 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (325 aa)
Snov_2362Transcriptional regulator, AsnC family; KEGG: azc:AZC_1147 transcriptional regulatory protein; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type. (158 aa)
Snov_2346Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
Snov_2344PFAM: major facilitator superfamily MFS_1; KEGG: nha:Nham_2864 twin-arginine translocation pathway signal. (455 aa)
Snov_2287KEGG: xau:Xaut_1513 EmrB/QacA family drug resistance transporter; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1. (523 aa)
Snov_2187KEGG: mag:amb3523 major facilitator superfamily permease; PFAM: major facilitator superfamily MFS_1; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein. (691 aa)
Snov_2105PFAM: Transcription regulator, AsnC-type-like; KEGG: azc:AZC_1825 putative transcriptional regulator. (78 aa)
Snov_2099PFAM: Mammalian cell entry related domain protein; KEGG: msl:Msil_2805 mammalian cell entry related domain protein. (348 aa)
Snov_2047PFAM: Luciferase-like, subgroup; KEGG: pde:Pden_0203 luciferase family protein. (369 aa)
Snov_2032KEGG: bja:blr1420 flavin dependant oxidoreductase; TIGRFAM: luciferase family oxidoreductase, group 1; PFAM: Luciferase-like, subgroup. (342 aa)
Snov_1927KEGG: azc:AZC_2820 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (599 aa)
Snov_1900KEGG: swi:Swit_4845 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (605 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (532 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (319 aa)
Snov_1811Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (129 aa)
Snov_4472KEGG: azc:AZC_4531 hypothetical protein. (380 aa)
Snov_4473KEGG: mpo:Mpop_1502 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; SMART: phospholipid/glycerol acyltransferase. (1138 aa)
Snov_1180KEGG: cak:Caul_0855 hypothetical protein. (143 aa)
Snov_1126KEGG: mes:Meso_3964 AsnC family transcriptional regulator; PFAM: Transcription regulator, AsnC-type-like; SMART: Transcription regulator, AsnC-type. (149 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
Snov_0985PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: gdj:Gdia_2700 peroxiredoxin. (217 aa)
Snov_0956PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_3371 putative multidrug efflux protein. (477 aa)
Snov_0892PFAM: major facilitator superfamily MFS_1; KEGG: bmj:BMULJ_00678 arabinose polymer transporter. (393 aa)
Snov_0870Alkanesulfonate monooxygenase; KEGG: ara:Arad_8153 FMNH2-dependent aliphatic sulfonate monooxygenase protein; PFAM: Luciferase-like, subgroup. (362 aa)
ssuDAlkanesulfonate monooxygenase, FMNH(2)-dependent; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family. (392 aa)
Snov_0849KEGG: xau:Xaut_3463 alkanesulfonate monooxygenase; PFAM: Luciferase-like, subgroup. (360 aa)
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (236 aa)
Snov_0800PFAM: extracellular solute-binding protein family 5; KEGG: mno:Mnod_0490 extracellular solute-binding protein family 5. (532 aa)
Snov_0799PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mno:Mnod_0489 binding-protein-dependent transport systems inner membrane component. (336 aa)
Snov_0798PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pol:Bpro_2813 binding-protein-dependent transport systems inner membrane component. (328 aa)
Snov_0661Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (198 aa)
Snov_4377PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_0571 major facilitator. (450 aa)
Snov_4346PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: bph:Bphy_5164 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. (225 aa)
Snov_4272PFAM: extracellular solute-binding protein family 5; KEGG: bbt:BBta_0882 putative ABC transporter, periplasmic binding protein. (554 aa)
Snov_4271PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bra:BRADO6822 putative dipeptide/oligopeptide/nickel ABC transporter, permease protein. (351 aa)
Snov_4270PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbt:BBta_0718 putative dipeptide/oligopeptide/nickel ABC transporter, permease protein. (278 aa)
Snov_4226PFAM: Luciferase-like, subgroup; KEGG: sen:SACE_4878 putative alkanesulfonate monooxygenase. (327 aa)
Snov_4179KEGG: fal:FRAAL0358 putative dibenzothiophene desulfurization enzyme A. (439 aa)
Snov_0596Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (159 aa)
Snov_4172KEGG: msm:MSMEG_6734 dibenzothiophene desulfurization enzyme A. (437 aa)
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (756 aa)
Snov_1317PFAM: FAD dependent oxidoreductase; KEGG: gau:GAU_0952 putative oxidoreductase. (297 aa)
Snov_4155KEGG: mlo:mlr9217 dibenzothiophene desulfurization enzyme. (436 aa)
Snov_4039Phosphate ABC transporter, periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
Snov_4003KEGG: azc:AZC_1030 putative proline/betaine transporter 1. (108 aa)
Snov_3985PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_1275 hypothetical protein. (410 aa)
Snov_3948PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_1369 major facilitator transporter. (412 aa)
Snov_3825PFAM: major facilitator superfamily MFS_1; KEGG: bac:BamMC406_6240 major facilitator transporter. (409 aa)
Snov_3763PFAM: major facilitator superfamily MFS_1; KEGG: bac:BamMC406_3472 major facilitator transporter. (426 aa)
Snov_3755KEGG: rlg:Rleg_5997 drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1. (519 aa)
Snov_3746PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_1369 major facilitator transporter. (511 aa)
Snov_3738PFAM: bifunctional deaminase-reductase domain protein; KEGG: met:M446_2359 deaminase-reductase domain-containing protein. (241 aa)
Snov_3620PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbr:BB4026 putative binding-protein-dependent permease. (310 aa)
Snov_3619PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tmz:Tmz1t_3550 binding-protein-dependent transport systems inner membrane component. (326 aa)
Snov_3618PFAM: extracellular solute-binding protein family 5; KEGG: aav:Aave_0936 extracellular solute-binding protein. (533 aa)
Snov_3596KEGG: xau:Xaut_2793 outer membrane autotransporter; TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein. (1796 aa)
Snov_3568KEGG: ara:Arad_9119 monooxygenase protein. (457 aa)
Snov_3503PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: oca:OCAR_5157 thioredoxin family protein. (196 aa)
Snov_3425Thioredoxin; KEGG: azc:AZC_4257 thioredoxin precursor; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain. (309 aa)
Snov_1294PFAM: major facilitator superfamily MFS_1; KEGG: xau:Xaut_3961 major facilitator transporter. (423 aa)
Snov_1285PFAM: major facilitator superfamily MFS_1; KEGG: azc:AZC_1275 hypothetical protein. (418 aa)
Snov_1284PFAM: FAD dependent oxidoreductase; KEGG: xau:Xaut_3968 putative secreted protein. (448 aa)
Snov_1279Phosphate ABC transporter, periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (339 aa)
msrA-2Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (217 aa)
Snov_1320PFAM: major facilitator superfamily MFS_1; KEGG: pjd:Pjdr2_0209 major facilitator superfamily MFS_1. (443 aa)
Snov_1337PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: mno:Mnod_6052 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. (155 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (65 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1376 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1396 aa)
Your Current Organism:
Starkeya novella
NCBI taxonomy Id: 639283
Other names: S. novella DSM 506, Starkeya novella DSM 506, Starkeya novella IAM 12100, Starkeya novella str. DSM 506, Starkeya novella strain DSM 506
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