node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Srot_0145 | Srot_2941 | Srot_0145 | Srot_2941 | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | 0.646 |
Srot_0145 | guaA | Srot_0145 | Srot_0828 | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.895 |
Srot_0145 | guaB | Srot_0145 | Srot_2940 | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.868 |
Srot_0145 | purA | Srot_0145 | Srot_1620 | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.996 |
Srot_2941 | Srot_0145 | Srot_2941 | Srot_0145 | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.646 |
Srot_2941 | guaA | Srot_2941 | Srot_0828 | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.999 |
Srot_2941 | guaB | Srot_2941 | Srot_2940 | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.972 |
Srot_2941 | purA | Srot_2941 | Srot_1620 | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.975 |
guaA | Srot_0145 | Srot_0828 | Srot_0145 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.895 |
guaA | Srot_2941 | Srot_0828 | Srot_2941 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | 0.999 |
guaA | guaB | Srot_0828 | Srot_2940 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purA | Srot_0828 | Srot_1620 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.929 |
guaB | Srot_0145 | Srot_2940 | Srot_0145 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.868 |
guaB | Srot_2941 | Srot_2940 | Srot_2941 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | 0.972 |
guaB | guaA | Srot_2940 | Srot_0828 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | purA | Srot_2940 | Srot_1620 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.988 |
purA | Srot_0145 | Srot_1620 | Srot_0145 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | TIGRFAM: adenylosuccinate lyase; KEGG: rop:ROP_48780 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.996 |
purA | Srot_2941 | Srot_1620 | Srot_2941 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | KEGG: rer:RER_19340 hypothetical protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase. | 0.975 |
purA | guaA | Srot_1620 | Srot_0828 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.929 |
purA | guaB | Srot_1620 | Srot_2940 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.988 |