STRINGSTRING
Srot_0746 Srot_0746 Srot_3072 Srot_3072 Srot_2949 Srot_2949 Srot_2948 Srot_2948 secY secY Srot_2806 Srot_2806 Srot_2805 Srot_2805 secE secE Srot_2495 Srot_2495 Srot_2494 Srot_2494 secA-2 secA-2 ftsY ftsY secA secA tatB tatB ffh ffh tig tig secF secF secD secD Srot_1452 Srot_1452 tatC tatC tatA tatA Srot_1100 Srot_1100 Srot_0785 Srot_0785 Srot_0786 Srot_0786 Srot_1099 Srot_1099 Srot_0308 Srot_0308 Srot_0309 Srot_0309 Srot_0620 Srot_0620
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Srot_0746PFAM: protein of unknown function DUF909; KEGG: msm:MSMEG_0621 low molecular weight protein antigen 7; Belongs to the WXG100 family. (95 aa)
Srot_3072KEGG: rop:ROP_34790 putative OxaA family protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein. (320 aa)
Srot_2949KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (95 aa)
Srot_2948PFAM: protein of unknown function DUF909; KEGG: bpu:BPUM_2860 hypothetical protein; Belongs to the WXG100 family. (99 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
Srot_2806KEGG: mav:MAV_4831 hypothetical protein; Belongs to the WXG100 family. (104 aa)
Srot_2805KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (99 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (163 aa)
Srot_2495PFAM: protein of unknown function DUF909; KEGG: mjl:Mjls_0060 10 kDa culture filtrate antigen LHP (CFP10); Belongs to the WXG100 family. (99 aa)
Srot_2494PFAM: protein of unknown function DUF909; KEGG: cgt:cgR_0698 hypothetical protein; Belongs to the WXG100 family. (96 aa)
secA-2SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (762 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (425 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (921 aa)
tatBTwin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (133 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (516 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (455 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (367 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (555 aa)
Srot_1452KEGG: mjl:Mjls_2314 preprotein translocase subunit YajC; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. (105 aa)
tatCSec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (288 aa)
tatATwin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (95 aa)
Srot_1100KEGG: mav:MAV_4643 hypothetical protein. (96 aa)
Srot_0785KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (97 aa)
Srot_0786KEGG: nfa:nfa42690 hypothetical protein; Belongs to the WXG100 family. (104 aa)
Srot_1099PFAM: protein of unknown function DUF909; KEGG: mul:MUL_5055 EsaT-6 like protein EsxF; Belongs to the WXG100 family. (109 aa)
Srot_0308KEGG: msm:MSMEG_1872 hypothetical protein; Belongs to the WXG100 family. (104 aa)
Srot_0309KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (99 aa)
Srot_0620Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (144 aa)
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.