STRINGSTRING
Srot_2494 Srot_2494 Srot_2495 Srot_2495 Srot_2549 Srot_2549 Srot_2551 Srot_2551 Srot_2612 Srot_2612 Srot_2629 Srot_2629 Srot_2697 Srot_2697 Srot_2698 Srot_2698 Srot_2699 Srot_2699 Srot_2719 Srot_2719 secE secE Srot_2782 Srot_2782 Srot_2805 Srot_2805 Srot_2806 Srot_2806 Srot_2834 Srot_2834 Srot_2848 Srot_2848 secY secY Srot_2948 Srot_2948 Srot_2949 Srot_2949 Srot_2969 Srot_2969 Srot_2997 Srot_2997 Srot_3005 Srot_3005 Srot_3027 Srot_3027 Srot_3028 Srot_3028 Srot_3072 Srot_3072 metN metN Srot_0104 Srot_0104 Srot_0105 Srot_0105 Srot_0266 Srot_0266 Srot_0269 Srot_0269 Srot_0270 Srot_0270 Srot_0308 Srot_0308 Srot_0309 Srot_0309 Srot_0388 Srot_0388 Srot_0552 Srot_0552 Srot_0620 Srot_0620 Srot_0746 Srot_0746 Srot_0770 Srot_0770 Srot_0785 Srot_0785 Srot_0786 Srot_0786 Srot_1046 Srot_1046 Srot_1047 Srot_1047 Srot_1050 Srot_1050 Srot_1099 Srot_1099 Srot_1100 Srot_1100 Srot_1122 Srot_1122 Srot_1247 Srot_1247 Srot_1342 Srot_1342 tatA tatA tatC tatC Srot_1452 Srot_1452 secD secD secF secF Srot_1455 Srot_1455 Srot_1537 Srot_1537 Srot_1557 Srot_1557 Srot_1622 Srot_1622 Srot_1623 Srot_1623 Srot_1630 Srot_1630 Srot_1670 Srot_1670 tig tig Srot_1929 Srot_1929 Srot_1930 Srot_1930 Srot_1931 Srot_1931 ffh ffh Srot_2038 Srot_2038 Srot_2044 Srot_2044 Srot_2046 Srot_2046 Srot_2050 Srot_2050 Srot_2051 Srot_2051 tatB tatB Srot_2158 Srot_2158 Srot_2169 Srot_2169 Srot_2195 Srot_2195 secA secA ftsY ftsY secA-2 secA-2 Srot_2301 Srot_2301 Srot_2333 Srot_2333 Srot_2409 Srot_2409
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Srot_2494PFAM: protein of unknown function DUF909; KEGG: cgt:cgR_0698 hypothetical protein; Belongs to the WXG100 family. (96 aa)
Srot_2495PFAM: protein of unknown function DUF909; KEGG: mjl:Mjls_0060 10 kDa culture filtrate antigen LHP (CFP10); Belongs to the WXG100 family. (99 aa)
Srot_2549KEGG: rer:RER_41440 ABC transporter ATP-binding protein; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (389 aa)
Srot_2551PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: svi:Svir_29500 putative threonine efflux protein. (208 aa)
Srot_2612KEGG: rer:RER_41290 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (389 aa)
Srot_2629KEGG: mab:MAB_2635c hypothetical protein. (571 aa)
Srot_2697PFAM: putative esterase; KEGG: rop:ROP_50250 mycolyltransferase. (338 aa)
Srot_2698PFAM: putative esterase; KEGG: rop:ROP_50250 mycolyltransferase. (335 aa)
Srot_2699PFAM: putative esterase; KEGG: rha:RHA1_ro04960 85 complex protein. (326 aa)
Srot_2719KEGG: rop:ROP_16520 putative ABC transporter ATP- binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (352 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (163 aa)
Srot_2782PFAM: protein of unknown function DUF6 transmembrane; KEGG: mab:MAB_3762 hypothetical protein. (370 aa)
Srot_2805KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (99 aa)
Srot_2806KEGG: mav:MAV_4831 hypothetical protein; Belongs to the WXG100 family. (104 aa)
Srot_2834PFAM: MMPL domain protein; KEGG: gbr:Gbro_4481 drug exporter of the RND superfamily-like protein. (983 aa)
Srot_2848PFAM: Xanthine/uracil/vitamin C permease; KEGG: mab:MAB_3353c putative xanthine/uracil/vitamin C permease family protein. (472 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
Srot_2948PFAM: protein of unknown function DUF909; KEGG: bpu:BPUM_2860 hypothetical protein; Belongs to the WXG100 family. (99 aa)
Srot_2949KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (95 aa)
Srot_2969PFAM: amino acid permease-associated region; KEGG: mab:MAB_3866c putative amino acid permease. (463 aa)
Srot_2997PFAM: protein of unknown function DUF1396; KEGG: mva:Mvan_2692 hypothetical protein. (232 aa)
Srot_3005PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: kra:Krad_3647 permease for cytosine/purines uracil thiamine allantoin; Belongs to the purine-cytosine permease (2.A.39) family. (463 aa)
Srot_3027KEGG: bcv:Bcav_1120 ABC transporter related; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase. (265 aa)
Srot_3028KEGG: mab:MAB_0722 putative oligopeptide ABC transporter, ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase. (490 aa)
Srot_3072KEGG: rop:ROP_34790 putative OxaA family protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein. (320 aa)
metNABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (351 aa)
Srot_0104PFAM: NLPA lipoprotein; KEGG: mab:MAB_2804c ABC transporter periplasmic protein. (314 aa)
Srot_0105PFAM: NLPA lipoprotein; KEGG: mab:MAB_2804c ABC transporter periplasmic protein. (301 aa)
Srot_0266KEGG: rop:ROP_34560 putative molybdate ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (313 aa)
Srot_0269KEGG: sen:SACE_1497 hypothetical protein. (235 aa)
Srot_0270PFAM: permease; KEGG: nfa:nfa40600 hypothetical protein. (328 aa)
Srot_0308KEGG: msm:MSMEG_1872 hypothetical protein; Belongs to the WXG100 family. (104 aa)
Srot_0309KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (99 aa)
Srot_0388PFAM: ABC-2 type transporter; KEGG: rer:RER_02600 ABC transporter permease protein. (286 aa)
Srot_0552PFAM: major facilitator superfamily MFS_1; KEGG: mmi:MMAR_2797 sialic acid-transport integral membrane protein NanT. (422 aa)
Srot_0620Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (144 aa)
Srot_0746PFAM: protein of unknown function DUF909; KEGG: msm:MSMEG_0621 low molecular weight protein antigen 7; Belongs to the WXG100 family. (95 aa)
Srot_0770KEGG: sma:SAV_5622 ABC transporter ATP-binding protein; PFAM: ABC transporter related; binding-protein- dependent transport systems inner membrane component; SMART: AAA ATPase. (682 aa)
Srot_0785KEGG: nfa:nfa42700 hypothetical protein; Belongs to the WXG100 family. (97 aa)
Srot_0786KEGG: nfa:nfa42690 hypothetical protein; Belongs to the WXG100 family. (104 aa)
Srot_1046PFAM: extracellular solute-binding protein family 5; KEGG: rha:RHA1_ro05349 ABC oligopeptide transporter, permease component. (560 aa)
Srot_1047TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: mbt:JTY_1315 putative oligopeptide-transport ATP-binding protein ABC transporter; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (623 aa)
Srot_1050PFAM: major facilitator superfamily MFS_1; KEGG: mab:MAB_0771c major facilitator transporter. (443 aa)
Srot_1099PFAM: protein of unknown function DUF909; KEGG: mul:MUL_5055 EsaT-6 like protein EsxF; Belongs to the WXG100 family. (109 aa)
Srot_1100KEGG: mav:MAV_4643 hypothetical protein. (96 aa)
Srot_1122ABC transporter related protein; KEGG: mbt:JTY_3722 putative dipeptide-transport ATP- binding protein ABC transporter; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (548 aa)
Srot_1247TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter related; KEGG: rer:RER_48150 ABC transporter permease/ATP- binding protein CydC; SMART: AAA ATPase. (553 aa)
Srot_1342PFAM: protein of unknown function DUF1396; KEGG: mmi:MMAR_1763 lipoprotein LppX. (243 aa)
tatATwin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (95 aa)
tatCSec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (288 aa)
Srot_1452KEGG: mjl:Mjls_2314 preprotein translocase subunit YajC; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. (105 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (555 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (367 aa)
Srot_1455PFAM: extracellular solute-binding protein family 5; KEGG: rop:ROP_68770 hypothetical protein. (548 aa)
Srot_1537KEGG: mpa:MAP2418 hypothetical protein. (150 aa)
Srot_1557PFAM: protein of unknown function DUF6 transmembrane; KEGG: bch:Bcen2424_5662 hypothetical protein. (309 aa)
Srot_1622KEGG: sgr:SGR_6812 putative ABC transporter permease protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component. (279 aa)
Srot_1623KEGG: ami:Amir_6886 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. (247 aa)
Srot_1630PFAM: protein of unknown function DUF6 transmembrane; KEGG: mab:MAB_0811 membrane protein (resistance to D-cycloserine). (308 aa)
Srot_1670PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: kse:Ksed_05080 putative threonine efflux protein. (212 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (455 aa)
Srot_1929PFAM: extracellular solute-binding protein family 1; KEGG: mab:MAB_1715c sugar ABC transporter, sugar- binding protein. (424 aa)
Srot_1930PFAM: amino acid permease-associated region; KEGG: mab:MAB_1132c L-asparagine ABC transporter permease. (522 aa)
Srot_1931PFAM: amino acid permease-associated region; KEGG: mab:MAB_1132c L-asparagine ABC transporter permease. (530 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (516 aa)
Srot_2038KEGG: rop:ROP_15920 putative PnuC family transporter; TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC. (227 aa)
Srot_2044PFAM: Mammalian cell entry related domain protein; KEGG: mab:MAB_4035 putative Mce family protein. (316 aa)
Srot_2046PFAM: Mammalian cell entry related domain protein; KEGG: mab:MAB_4033 putative Mce family protein. (375 aa)
Srot_2050PFAM: protein of unknown function DUF140; KEGG: mab:MAB_4029 putative YrbE family protein. (290 aa)
Srot_2051PFAM: protein of unknown function DUF140; KEGG: mab:MAB_4028 putative YrbE family protein. (280 aa)
tatBTwin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (133 aa)
Srot_2158KEGG: nml:Namu_0261 xanthine permease; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (681 aa)
Srot_2169PFAM: amino acid permease-associated region; KEGG: ach:Achl_3893 amino acid permease-associated region. (475 aa)
Srot_2195PFAM: protein of unknown function DUF6 transmembrane; KEGG: oan:Oant_1003 hypothetical protein. (307 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (921 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (425 aa)
secA-2SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (762 aa)
Srot_2301PFAM: protein of unknown function DUF6 transmembrane; KEGG: sen:SACE_2131 hypothetical protein. (278 aa)
Srot_2333PFAM: ABC-2 type transporter; KEGG: mab:MAB_2753 ABC transporter permease. (258 aa)
Srot_2409PFAM: MMPL domain protein; KEGG: mgi:Mflv_2131 MmpL domain-containing protein. (738 aa)
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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