STRINGSTRING
Srot_1582 Srot_1582 glcB glcB Srot_1806 Srot_1806 Srot_2049 Srot_2049 Srot_2137 Srot_2137 Srot_2168 Srot_2168 Srot_2178 Srot_2178 Srot_2185 Srot_2185 Srot_2208 Srot_2208 Srot_2428 Srot_2428 Srot_2494 Srot_2494 Srot_2598 Srot_2598 Srot_2624 Srot_2624 Srot_2627 Srot_2627 Srot_2739 Srot_2739 Srot_2769 Srot_2769 Srot_2770 Srot_2770 cpdA cpdA Srot_2838 Srot_2838 metN metN fgd fgd Srot_0142 Srot_0142 Srot_0176 Srot_0176 Srot_0542 Srot_0542 Srot_0779 Srot_0779 mutM mutM Srot_0930 Srot_0930 Srot_1136 Srot_1136 dnaK dnaK Srot_1457 Srot_1457 Srot_1508 Srot_1508 Srot_1579 Srot_1579
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Srot_1582KEGG: msm:MSMEG_6454 hypothetical protein; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (280 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (726 aa)
Srot_1806PFAM: CDP-alcohol phosphatidyltransferase; KEGG: gbr:Gbro_2289 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (248 aa)
Srot_2049PFAM: Mammalian cell entry related domain protein; KEGG: mab:MAB_4030 putative Mce family protein. (422 aa)
Srot_2137Adenosinetriphosphatase; PFAM: AAA ATPase central domain protein; KEGG: nfa:nfa52890 putative AAA ATPase; SMART: AAA ATPase; Belongs to the AAA ATPase family. (741 aa)
Srot_2168Putative F420-dependent oxidoreductase; KEGG: rha:RHA1_ro02495 5,10- methylenetetrahydromethanopterin reductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (342 aa)
Srot_2178Putative F420-dependent oxidoreductase; KEGG: rha:RHA1_ro02495 5,10- methylenetetrahydromethanopterin reductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (323 aa)
Srot_2185TIGRFAM: urate catabolism protein; KEGG: msm:MSMEG_5728 polysaccharide deacetylase family protein; PFAM: polysaccharide deacetylase. (300 aa)
Srot_2208KEGG: nfa:nfa55380 hypothetical protein. (291 aa)
Srot_2428PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; KEGG: msm:MSMEG_1756 endonuclease VIII and DNA N- glycosylase with an AP lyase activity. (248 aa)
Srot_2494PFAM: protein of unknown function DUF909; KEGG: cgt:cgR_0698 hypothetical protein; Belongs to the WXG100 family. (96 aa)
Srot_2598KEGG: mjl:Mjls_0897 putative monooxygenase. (473 aa)
Srot_2624Catalase; KEGG: mmi:MMAR_5217 catalase KatE; PFAM: Catalase related subgroup; Catalase domain protein. (486 aa)
Srot_2627PFAM: heat shock protein Hsp20; KEGG: mab:MAB_4402 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (166 aa)
Srot_2739KEGG: nfa:nfa15760 hypothetical protein. (142 aa)
Srot_2769KEGG: rop:ROP_39410 putative oxidoreductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (345 aa)
Srot_2770PFAM: cutinase; KEGG: rop:ROP_39400 hypothetical protein. (347 aa)
cpdAMetallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (315 aa)
Srot_2838KEGG: mab:MAB_3016c hypothetical protein. (279 aa)
metNABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (351 aa)
fgdF420-dependent oxidoreductase, G6PDH family; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. (335 aa)
Srot_0142KEGG: rer:RER_59100 hypothetical protein. (252 aa)
Srot_0176KEGG: mjl:Mjls_2657 hypothetical protein. (271 aa)
Srot_0542Putative F420-dependent oxidoreductase; KEGG: mab:MAB_0968c luciferase-like hypothetical protein; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (301 aa)
Srot_0779KEGG: gbr:Gbro_0072 flavin-containing monooxygenase FMO. (505 aa)
mutMformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (283 aa)
Srot_0930CDP-diacylglycerol/glycerol-3-phosphate3- phosphatidyl transferase; KEGG: rer:RER_27390 phosphatidylglycerophosphate synthase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (197 aa)
Srot_1136KEGG: mab:MAB_3748 putative luciferase-like oxidoreductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (345 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (618 aa)
Srot_1457(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (797 aa)
Srot_1508Alkanesulfonate monooxygenase; KEGG: mmi:MMAR_4200 F420-dependent glucose-6- phosphate dehydrogenase Fgd2. (387 aa)
Srot_15795,10-methylenetetrahydromethanopterin reductase; KEGG: kra:Krad_4268 luciferase family protein; PFAM: Luciferase-like, subgroup. (341 aa)
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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